Gpatch8

Functionⁱ

Regions

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Zinc fingerⁱ	136 – 160	C2H2-typePROSITE-ProRule annotationAdd BLAST		25

GO - Molecular functionⁱ

metal ion binding Source: UniProtKB-KW
nucleic acid binding Source: InterPro

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Ligand	Metal-binding, Zinc

Ligand

Metal-binding, Zinc

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: G patch domain-containing protein 8
Gene namesⁱ	Name:Gpatch8 Synonyms:Gpatc8, Kiaa0553
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 11

Organism-specific databases

MGIⁱ	MGI:1918667 Gpatch8

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000379799	1 – 1505	G patch domain-containing protein 8Add BLAST		1505

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Cross-linkⁱ	311	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residueⁱ	479	N6-acetyllysineCombined sources	1
Cross-linkⁱ	573	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residueⁱ	648	PhosphoserineBy similarity	1
Modified residueⁱ	733	PhosphoserineBy similarity	1
Modified residueⁱ	735	PhosphoserineBy similarity	1
Modified residueⁱ	753	PhosphoserineBy similarity	1
Modified residueⁱ	915	PhosphoserineCombined sources	1
Modified residueⁱ	918	PhosphoserineCombined sources	1
Modified residueⁱ	985	PhosphoserineBy similarity	1
Modified residueⁱ	1013	PhosphoserineBy similarity	1
Modified residueⁱ	1018	PhosphoserineBy similarity	1
Modified residueⁱ	1037	PhosphoserineBy similarity	1
Modified residueⁱ	1039	PhosphoserineBy similarity	1
Modified residueⁱ	1085	PhosphoserineBy similarity	1
Cross-linkⁱ	1109	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residueⁱ	1179	PhosphoserineCombined sources	1

Keywords - PTMⁱ

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

EPDⁱ	A2A6A1
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	A2A6A1
PaxDbⁱ	A2A6A1
PeptideAtlas More...PeptideAtlasⁱ	A2A6A1
PRIDEⁱ	A2A6A1

PTM databases

iPTMnetⁱ	A2A6A1
PhosphoSitePlusⁱ	A2A6A1

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000034621 Expressed in 271 organ(s), highest expression level in cochlea
Genevisibleⁱ	A2A6A1 MM

Interactionⁱ

Protein-protein interaction databases

BioGridⁱ	231931, 1 interactor
STRINGⁱ	10090.ENSMUSP00000120649

Structureⁱ

3D structure databases

SMRⁱ	A2A6A1
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	40 – 86	G-patchPROSITE-ProRule annotationAdd BLAST		47

Coiled coil

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Coiled coilⁱ	89 – 124	Sequence analysisAdd BLAST		36

Compositional bias

Feature key	Position(s)	DescriptionActions	Length
Compositional biasⁱ	660 – 715	Lys-richAdd BLAST	56
Compositional biasⁱ	740 – 744	Poly-Arg	5
Compositional biasⁱ	767 – 770	Poly-Gly	4
Compositional biasⁱ	799 – 1013	Ser-richAdd BLAST	215
Compositional biasⁱ	833 – 852	Glu-richAdd BLAST	20
Compositional biasⁱ	1387 – 1393	Poly-Ala	7
Compositional biasⁱ	1475 – 1481	Poly-Ala	7

Zinc finger

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Zinc fingerⁱ	136 – 160	C2H2-typePROSITE-ProRule annotationAdd BLAST		25

Keywords - Domainⁱ

Coiled coil, Zinc-finger

Phylogenomic databases

eggNOGⁱ	ENOG410IGVP Eukaryota ENOG410ZHVS LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00530000063305
HOGENOMⁱ	HOG000231046
InParanoidⁱ	A2A6A1
OMAⁱ	SPKPKGC
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G01DY
PhylomeDBⁱ	A2A6A1
TreeFamⁱ	TF332138

Family and domain databases

InterProⁱ	View protein in InterPro IPR000467 G_patch_dom IPR022755 Znf_C2H2_jaz IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01585 G-patch, 1 hit PF12171 zf-C2H2_jaz, 1 hit
SMARTⁱ	View protein in SMART SM00443 G_patch, 1 hit
SUPFAMⁱ	SSF57667 SSF57667, 1 hit
PROSITEⁱ	View protein in PROSITE PS50174 G_PATCH, 1 hit PS00028 ZINC_FINGER_C2H2_1, 1 hit PS50157 ZINC_FINGER_C2H2_2, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

A2A6A1-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MADRFSRFNE DRDFQGNHFD QYEEGHLEIE QASLDKPIES DNIGHRLLQK 
        60         70         80         90        100
HGWKLGQGLG KSLQGRTDPI PIVVKYDVMG MGRMEMELDY AEDATERRRV 
       110        120        130        140        150
LEVEKEDTEE LRQKYKDYVD KEKAIAKALE DLRANFYCEL CDKQYQKHQE 
       160        170        180        190        200
FDNHINSYDH AHKQRLKDLK QREFARNVSS RSRKDEKKQE KALRRLHELA 
       210        220        230        240        250
EQRKQAECAP GSGPMFRPTT VAVDEDGGEE DKDESSTNSG ASAVSSCGFG 
       260        270        280        290        300
ADFSTDKGGS FTSVQITNTT GLSQAPGLAS QGISFGIKNN LGPPLQKLGV 
       310        320        330        340        350
SFSFAKKAPV KLESIASVFK DHAEEGSSED GTKADEKSSD QGVQKVGDTD 
       360        370        380        390        400
GTGNLDGKKE DEDPQDGGSL ASTLSKLKRM KREEGTGATE PEYYHYIPPA 
       410        420        430        440        450
HCKVKPNFPF LLFMRASEQM EGDHSAHSKS APENRKSSSP KPQGCSKTAA 
       460        470        480        490        500
SPGAERTVSE ASELQKEAAV AGPSEPGGKT ETKKGSGGGE DEQSVESRET 
       510        520        530        540        550
SESPMCESNP KDISQATPAT KAGQGPKHPT GPFFPVLSKD ESTALQWPSE 
       560        570        580        590        600
LLIFTKAEPS ISYSCNPLYF DFKLSRNKDA KAKGTEKPKD VAGSSKDHLQ 
       610        620        630        640        650
SLDPREPNKS QEEEQDVVLS SEGRVDEPAS GAACSSLNKQ EPGGSHMSET 
       660        670        680        690        700
EDTGRSHPSK KEPSGKSHRH KKKKKHKKSS KHKRKHKADT EEKSSKAESG 
       710        720        730        740        750
EKSKKRKKRK RKKNKSSAAA DSERGPKSEP PGSGSPAPPR RRRRAQDDSQ 
       760        770        780        790        800
RRSLPAEEGN SGKKDDGGGG SSCQDHSGRK HKGEPPTSSC QRRANTKHSS 
       810        820        830        840        850
RSSHRSQPSS GDEDSDDASS HRLHQKSPSQ YSEEEEEEEE EEEEEDEDSG 
       860        870        880        890        900
SEHSRSRSRS GHRHSSHRSS RRSYSSSSDA SSDQSCYSRQ HSYSDDSYSD 
       910        920        930        940        950
YSDRSRRHSK RSHDSDDSDY TSSKHRSKRH KYSSSDDDYS LSCSQSRSRS 
       960        970        980        990       1000
RSHTRERSRS RGRSRSSSCS RSRSKRRSRS TTAHSWQRSR SYSRDRSRST 
      1010       1020       1030       1040       1050
RSPSQRSGSR KGSWGHESPE ERRSGRRDFI RSKIYRSQSP HYFQSGRGEG 
      1060       1070       1080       1090       1100
PGKKEDGRGD DSKGAGLPSQ NSNTGTGRGS ESDCSPEDKN SVTARLLLEK 
      1110       1120       1130       1140       1150
IQSRKVERKP NVCEEVLATP NKAGLKYKNP PQGYFGPKLP PSLGNKPVLP 
      1160       1170       1180       1190       1200
MIGKLPATRK SNKKCEESGL ERGEEQEHSE PEEGSPRSSD APFGHQFSEE 
      1210       1220       1230       1240       1250
AAGPLSDPPP EEPKSEEATA DHSVAPLGTP AHTDCYPGDP AISHNYLPDP 
      1260       1270       1280       1290       1300
SDGDTLESLD SGSQPGPVES SLLPIAPDLE HFPNYAPPSG EPSIESTDGT 
      1310       1320       1330       1340       1350
EDASLAPLES QPITFTPEEM EKYSKLQQAA QQHIQQQLLA KQVKAFPAST 
      1360       1370       1380       1390       1400
ALAPATPALQ PIHIQQPATA SATSITTVQH AILQHHAAAA AAAIGIHPHP 
      1410       1420       1430       1440       1450
HPQPLAQVHH IPQPHLTPIS LSHLTHSIIP GHPATFLASH PIHIIPASAI 
      1460       1470       1480       1490       1500
HPGPFTFHPV PHAALYPTLL APRPAAAAAT ALHLHPLLHP IFSGQDLQHP 

PSHGT

Length:1,505

Mass (Da):164,987

Last modified:February 20, 2007 - v1

Checksum:ⁱ0BCC873DA8AE6DDF

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	954	T → I in BAC65589 (PubMed:12693553).Curated		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL596258 Genomic DNA No translation available. AK122307 mRNA Translation: BAC65589.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS48944.1
NCBI Reference Sequences More...RefSeqⁱ	NP_001152964.1, NM_001159492.1
UniGeneⁱ	Mm.260282

Genome annotation databases

Ensemblⁱ	ENSMUST00000143842; ENSMUSP00000120649; ENSMUSG00000034621
GeneIDⁱ	237943
KEGGⁱ	mmu:237943
UCSC genome browser More...UCSCⁱ	uc007lsb.2 mouse

Protein	Similar proteins		Species	Score	Length	Source
A2A6A1	G patch domain-containing protein 8		HUMAN		1502	UniRef90_Q9UKJ3
Uncharacterized protein		PIG		1645
G patch domain-containing protein 8		MYOBR		1562
G patch domain-containing protein 8		CASCN		1510
G-patch domain containing 8		BOVIN		1509
+198

Protein	Similar proteins		Species	Score	Length	Source
A2A6A1	G patch domain-containing protein 8		HUMAN		1502	UniRef50_Q9UKJ3
Uncharacterized protein		PIG		1645
G patch domain-containing protein 8		MYOBR		1562
G patch domain-containing protein 8		CASCN		1510
G-patch domain containing 8		BOVIN		1509
+389

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL596258 Genomic DNA No translation available. AK122307 mRNA Translation: BAC65589.1
CCDSⁱ	CCDS48944.1
RefSeqⁱ	NP_001152964.1, NM_001159492.1
UniGeneⁱ	Mm.260282

3D structure databases

SMRⁱ	A2A6A1
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	231931, 1 interactor
STRINGⁱ	10090.ENSMUSP00000120649

PTM databases

iPTMnetⁱ	A2A6A1
PhosphoSitePlusⁱ	A2A6A1

Proteomic databases

EPDⁱ	A2A6A1
MaxQBⁱ	A2A6A1
PaxDbⁱ	A2A6A1
PeptideAtlasⁱ	A2A6A1
PRIDEⁱ	A2A6A1

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000143842; ENSMUSP00000120649; ENSMUSG00000034621
GeneIDⁱ	237943
KEGGⁱ	mmu:237943
UCSCⁱ	uc007lsb.2 mouse

Organism-specific databases

CTDⁱ	23131
MGIⁱ	MGI:1918667 Gpatch8
Rougeⁱ	Search...

Phylogenomic databases

eggNOGⁱ	ENOG410IGVP Eukaryota ENOG410ZHVS LUCA
GeneTreeⁱ	ENSGT00530000063305
HOGENOMⁱ	HOG000231046
InParanoidⁱ	A2A6A1
OMAⁱ	SPKPKGC
OrthoDBⁱ	EOG091G01DY
PhylomeDBⁱ	A2A6A1
TreeFamⁱ	TF332138

Miscellaneous databases

ChiTaRSⁱ	Gpatch8 mouse
Protein Ontology More...PROⁱ	PR:A2A6A1
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000034621 Expressed in 271 organ(s), highest expression level in cochlea
Genevisibleⁱ	A2A6A1 MM

Family and domain databases

InterProⁱ	View protein in InterPro IPR000467 G_patch_dom IPR022755 Znf_C2H2_jaz IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
Pfamⁱ	View protein in Pfam PF01585 G-patch, 1 hit PF12171 zf-C2H2_jaz, 1 hit
SMARTⁱ	View protein in SMART SM00443 G_patch, 1 hit
SUPFAMⁱ	SSF57667 SSF57667, 1 hit
PROSITEⁱ	View protein in PROSITE PS50174 G_PATCH, 1 hit PS00028 ZINC_FINGER_C2H2_1, 1 hit PS50157 ZINC_FINGER_C2H2_2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	GPTC8_MOUSE
Accessionⁱ	A2A6A1Primary (citable) accession number: A2A6A1 Secondary accession number(s): Q80TY1
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
	Last sequence update:	February 20, 2007
	Last modified:	November 7, 2018
	This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - A2A6A1 (GPTC8_MOUSE)

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G patch domain-containing protein 8

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Coiled coil

Compositional bias

Zinc finger

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ