UniProtKB - A2A699 (F1712_MOUSE)
Protein
Protein FAM171A2
Gene
Fam171a2
Organism
Mus musculus (Mouse)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Protein FAM171A2 |
Gene namesi | Name:Fam171a2 |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:2448496, Fam171a2 |
Subcellular locationi
Other locations
- Membrane Curated; Single-pass type I membrane protein Curated
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 30 – 315 | ExtracellularSequence analysisAdd BLAST | 286 | |
Transmembranei | 316 – 336 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 337 – 822 | CytoplasmicSequence analysisAdd BLAST | 486 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 29 | Sequence analysisAdd BLAST | 29 | |
ChainiPRO_0000328772 | 30 – 822 | Protein FAM171A2Add BLAST | 793 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 66 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 201 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 221 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 265 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Modified residuei | 369 | PhosphoserineCombined sources | 1 | |
Modified residuei | 371 | PhosphoserineCombined sources | 1 | |
Modified residuei | 785 | PhosphoserineCombined sources | 1 |
Keywords - PTMi
Glycoprotein, PhosphoproteinProteomic databases
EPDi | A2A699 |
jPOSTi | A2A699 |
MaxQBi | A2A699 |
PaxDbi | A2A699 |
PeptideAtlasi | A2A699 |
PRIDEi | A2A699 |
PTM databases
GlyConnecti | 2627, 4 N-Linked glycans (2 sites) |
GlyGeni | A2A699, 4 sites |
iPTMneti | A2A699 |
PhosphoSitePlusi | A2A699 |
SwissPalmi | A2A699 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000034685, Expressed in cortical plate and 175 other tissues |
Genevisiblei | A2A699, MM |
Interactioni
Protein-protein interaction databases
BioGRIDi | 229868, 3 interactors |
IntActi | A2A699, 3 interactors |
STRINGi | 10090.ENSMUSP00000038486 |
Miscellaneous databases
RNActi | A2A699, protein |
Family & Domainsi
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 710 – 718 | Poly-Pro | 9 |
Sequence similaritiesi
Belongs to the FAM171 family.Curated
Keywords - Domaini
Signal, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | ENOG502QTDH, Eukaryota |
GeneTreei | ENSGT00950000183184 |
HOGENOMi | CLU_019729_0_0_1 |
InParanoidi | A2A699 |
OMAi | RPLMVFH |
OrthoDBi | 615320at2759 |
PhylomeDBi | A2A699 |
TreeFami | TF331338 |
Family and domain databases
InterProi | View protein in InterPro IPR018890, Uncharacterised_FAM171 |
PANTHERi | PTHR31626, PTHR31626, 1 hit |
Pfami | View protein in Pfam PF10577, UPF0560, 1 hit |
s (2)i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketIsoform 1 (identifier: A2A699-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MPPPSGPGVL ARLLPLLGLL LGGASRAPGK SPPEPPSPQE ILIKVQVYVS
60 70 80 90 100
GELVPLARAS VDVFGNRTLL AAGTTDSEGV ATLPLSYRLG TWVLVTAARP
110 120 130 140 150
GFLTNSVPWR VDKLPLYASV SLYLLPERPA TLILYEDLVH ILLGSPGARS
160 170 180 190 200
QPWVQFQRRA ARLPVSSTYS QLWASLTPAS TQQEMRAFPA FLGTEASSSG
210 220 230 240 250
NGSWLELIPL AAVSVHLLTG NGTEVPLSGP IHLSLPVPSE PRALAVGTSI
260 270 280 290 300
PAWRFDPKSG LWVRNGTGVI RKEGRQLYWT FVSPQLGYWV AAMASPTSGL
310 320 330 340 350
VTITSGIQDI GTYHTIFLLT ILAALALLVL ILLCLLIYYC RRRCLKPRQQ
360 370 380 390 400
HRKLQLSGPS DNKRDQATSM SQLHLICGGP LEPTSSGDPE APPPGSLHSA
410 420 430 440 450
FSSSRDLASS RDDFFRAKPR SASRPAAEPP GARTVEGAGL KSARSVEGPG
460 470 480 490 500
GLEPSLDEYR RGPAGAAAFL HEPPSPPPSF DHYLGHKGAA ESKTPDFLLS
510 520 530 540 550
QSVDQLARPP SLSQPGQLIF CGSIDHLKDN VYRNVMPTLV IPAHYVRLGG
560 570 580 590 600
EAGAAGVGDE ATPPEGSAAG PARPFPQPDP QRPLMQGHAG AGGDSGGGEG
610 620 630 640 650
WGGGRSAPVS GSVTIPVLFN ESTMAQLNGE LQALTEKKLL ELGVKPHPRA
660 670 680 690 700
WFVSLDGRSN SQVRHSYIDL QAGSGGRSTD ASLDSGVDVH EARPARRRLP
710 720 730 740 750
REERERAQLP APPPPAPPRL ALSEDTEPSS SESRTGLCSP EDNSLTPLLD
760 770 780 790 800
EVVAPEGRAA TVPRGRGRSR GDSSRSSASE LRRDSLTSPE DELGAEVGDE
810 820
AGDKKSPWQR REERPLMVFN VK
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_032783 | 1 – 184 | Missing in isoform 2. 1 PublicationAdd BLAST | 184 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL596258 Genomic DNA No translation available. BC025575 mRNA Translation: AAH25575.1 BC064455 mRNA Translation: AAH64455.1 |
CCDSi | CCDS36344.1 [A2A699-1] |
RefSeqi | NP_954670.2, NM_199200.2 [A2A699-1] |
Genome annotation databases
Ensembli | ENSMUST00000049057; ENSMUSP00000038486; ENSMUSG00000034685 [A2A699-1] |
GeneIDi | 217219 |
KEGGi | mmu:217219 |
UCSCi | uc007lrw.2, mouse [A2A699-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL596258 Genomic DNA No translation available. BC025575 mRNA Translation: AAH25575.1 BC064455 mRNA Translation: AAH64455.1 |
CCDSi | CCDS36344.1 [A2A699-1] |
RefSeqi | NP_954670.2, NM_199200.2 [A2A699-1] |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 229868, 3 interactors |
IntActi | A2A699, 3 interactors |
STRINGi | 10090.ENSMUSP00000038486 |
PTM databases
GlyConnecti | 2627, 4 N-Linked glycans (2 sites) |
GlyGeni | A2A699, 4 sites |
iPTMneti | A2A699 |
PhosphoSitePlusi | A2A699 |
SwissPalmi | A2A699 |
Proteomic databases
EPDi | A2A699 |
jPOSTi | A2A699 |
MaxQBi | A2A699 |
PaxDbi | A2A699 |
PeptideAtlasi | A2A699 |
PRIDEi | A2A699 |
Protocols and materials databases
Antibodypediai | 8250, 27 antibodies |
Genome annotation databases
Ensembli | ENSMUST00000049057; ENSMUSP00000038486; ENSMUSG00000034685 [A2A699-1] |
GeneIDi | 217219 |
KEGGi | mmu:217219 |
UCSCi | uc007lrw.2, mouse [A2A699-1] |
Organism-specific databases
CTDi | 284069 |
MGIi | MGI:2448496, Fam171a2 |
Phylogenomic databases
eggNOGi | ENOG502QTDH, Eukaryota |
GeneTreei | ENSGT00950000183184 |
HOGENOMi | CLU_019729_0_0_1 |
InParanoidi | A2A699 |
OMAi | RPLMVFH |
OrthoDBi | 615320at2759 |
PhylomeDBi | A2A699 |
TreeFami | TF331338 |
Miscellaneous databases
BioGRID-ORCSi | 217219, 2 hits in 17 CRISPR screens |
ChiTaRSi | Fam171a2, mouse |
PROi | PR:A2A699 |
RNActi | A2A699, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000034685, Expressed in cortical plate and 175 other tissues |
Genevisiblei | A2A699, MM |
Family and domain databases
InterProi | View protein in InterPro IPR018890, Uncharacterised_FAM171 |
PANTHERi | PTHR31626, PTHR31626, 1 hit |
Pfami | View protein in Pfam PF10577, UPF0560, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F1712_MOUSE | |
Accessioni | A2A699Primary (citable) accession number: A2A699 Secondary accession number(s): B7ZC48, Q05CH6, Q6P2L1 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 8, 2008 |
Last sequence update: | February 20, 2007 | |
Last modified: | February 10, 2021 | |
This is version 93 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families