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Entry version 113 (16 Oct 2019)
Sequence version 1 (20 Feb 2007)
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Protein

Protein TANC2

Gene

Tanc2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein TANC2
Alternative name(s):
Tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Tanc2
Synonyms:Kiaa1148
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2444121 Tanc2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003338121 – 1994Protein TANC2Add BLAST1994

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei169PhosphoserineBy similarity1
Modified residuei238PhosphoserineBy similarity1
Modified residuei294PhosphoserineBy similarity1
Modified residuei400PhosphoserineBy similarity1
Modified residuei1446PhosphoserineBy similarity1
Modified residuei1462PhosphoserineBy similarity1
Modified residuei1534PhosphoserineBy similarity1
Modified residuei1549PhosphoserineBy similarity1
Modified residuei1567Asymmetric dimethylarginineCombined sources1
Modified residuei1580Asymmetric dimethylarginineCombined sources1
Modified residuei1583PhosphoserineCombined sources1
Modified residuei1726PhosphoserineBy similarity1
Modified residuei1828PhosphoserineCombined sources1
Modified residuei1831PhosphoserineCombined sources1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi1932N-linked (GlcNAc...) asparagine1 Publication1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Glycoprotein, Methylation, Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
A2A690

MaxQB - The MaxQuant DataBase

More...
MaxQBi
A2A690

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
A2A690

PeptideAtlas

More...
PeptideAtlasi
A2A690

PRoteomics IDEntifications database

More...
PRIDEi
A2A690

PTM databases

GlyConnect protein glycosylation platform

More...
GlyConnecti
696

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
A2A690

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
A2A690

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
A2A690

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000053580 Expressed in 236 organ(s), highest expression level in cerebral cortex

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A2A690 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
A2A690 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
218515, 4 interactors

Protein interaction database and analysis system

More...
IntActi
A2A690, 2 interactors

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000097904

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A2A690

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati846 – 878ANK 1Add BLAST33
Repeati884 – 913ANK 2Add BLAST30
Repeati917 – 946ANK 3Add BLAST30
Repeati950 – 979ANK 4Add BLAST30
Repeati990 – 1019ANK 5Add BLAST30
Repeati1033 – 1062ANK 6Add BLAST30
Repeati1066 – 1095ANK 7Add BLAST30
Repeati1099 – 1128ANK 8Add BLAST30
Repeati1132 – 1161ANK 9Add BLAST30
Repeati1165 – 1194ANK 10Add BLAST30
Repeati1198 – 1227ANK 11Add BLAST30
Repeati1244 – 1277TPR 1Add BLAST34
Repeati1291 – 1324TPR 2Add BLAST34
Repeati1325 – 1358TPR 3Add BLAST34

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TANC family.Curated

Keywords - Domaini

ANK repeat, Repeat, TPR repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0504 Eukaryota
COG0666 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156447

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000231045

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
A2A690

Identification of Orthologs from Complete Genome Data

More...
OMAi
ACDELSP

Database of Orthologous Groups

More...
OrthoDBi
1073736at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
A2A690

TreeFam database of animal gene trees

More...
TreeFami
TF323159

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.10, 1 hit
1.25.40.20, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR027417 P-loop_NTPase
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00023 Ank, 1 hit
PF12796 Ank_2, 3 hits
PF13181 TPR_8, 2 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01415 ANKYRIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00248 ANK, 11 hits
SM00028 TPR, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48403 SSF48403, 1 hit
SSF48452 SSF48452, 1 hit
SSF52540 SSF52540, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 6 hits
PS50005 TPR, 3 hits
PS50293 TPR_REGION, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 5 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: A2A690-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MFRNSLKMLL TGGKSSRKNR SSDGGSEEPP DRRQSSVDSR QSRSGQGGIS
60 70 80 90 100
TESDCAFEPD YAVPPLPVSE GDVEQELGPP PSVDEAANTL MTRLGFLLGE
110 120 130 140 150
KVTEVQPSDQ YSMEVQDENQ TSAITQRISP CSTLTSSTAS PPASSPCSTL
160 170 180 190 200
PPVSTNAAAK DCSYGAVTSP TSTLESRDSG IIATLTNYSE NMERTKYVGE
210 220 230 240 250
GSKELGSGGN LKPWQSQKSS MDSCLYRVDE NMAASTYSLN KIPERNLETV
260 270 280 290 300
LSQSVQSIPL YLMPRPNSVA ATSSAHLEDL AYLDEQRHTP LRTSLRMPRQ
310 320 330 340 350
SLSGARTQQD LRVRFAPYRP PDISLKPLLF EVPSITTESV FVGRDWVFHE
360 370 380 390 400
IDAQLQSSNA SVNQGVVIVG NIGFGKTAII SRLVALSCHG TRMRQIASDS
410 420 430 440 450
PHASPKHVDA NRELPLTQAP SAHSSITSGS CPGTPEMRRR QEEAMRRLAS
460 470 480 490 500
QVVAYHYCQA DNAYTCLVPE FVHNVAALLC RSPQLTAYRE QLLREPHLQS
510 520 530 540 550
MLSLRSCVQD PMASFRRGVL EPLENLHKER KIPDEDFIIL IDGLNEAEFH
560 570 580 590 600
KPDYGDTIVS FLSKMIGNFP SWLKLIVTVR TSLQEITKLL PFHRIFLDRL
610 620 630 640 650
EENEAIDQDL QAYILHRIHS SSEIQNNISL NGKMDNTTFG KLSSHLKTLS
660 670 680 690 700
QGSYLYLKLT FDLIEKGYLV LKSSSYKVVP VSLSEVYLLQ CNMKFPTQSS
710 720 730 740 750
FDRVMPLLNV AVASLHPLTD EHIFQAINAG SIEGTLEWED FQQRMENLSM
760 770 780 790 800
FLIKRRDMTR MFVHPSFREW LIWREEGEKT KFLCDPRSGH TLLAFWFSRQ
810 820 830 840 850
EGKLNRQQTI ELGHHILKAH IFKGLSKKVG VSSSILQGLW ISYSTEGLSM
860 870 880 890 900
ALASLRNLYT PNIKVSRLLI LGGANINYRT EVLNNAPILC VQSHLGYTEM
910 920 930 940 950
VALLLEFGAN VDASSESGLT PLGYAAAAGF LSIVVLLCKK RAKVDHLDKN
960 970 980 990 1000
GQCALVHAAL RGHLEVVKFL IQCDWTMAGQ QQGVFKKSHA IQQALIAAAS
1010 1020 1030 1040 1050
MGYTEIVSYL LDLPEKDEEE VERAQINSFD SLWGETALTA AAGRGKLDVC
1060 1070 1080 1090 1100
RLLLEQGAAV AQPNRRGAVP LFSTVRQGHW QIVDLLLTHG ADVNMADKQG
1110 1120 1130 1140 1150
RTPLMMAASE GHLGTVDFLL AQGASIALMD KEGLTALSWA CLKGHLSVVR
1160 1170 1180 1190 1200
SLVDNGAATD HADKNGRTPL DLAAFYGDAE VVQFLVDHGA MIEHVDYSGM
1210 1220 1230 1240 1250
RPLDRAVGCR NTSVVVTLLK KGAKIGPATW AMATSKPDIM IILLSKLMEE
1260 1270 1280 1290 1300
GDMFYKKGKV KEAAQRYQYA LKKFPREGFG EDLKTFRELK VSLLLNLSRC
1310 1320 1330 1340 1350
RRKMNDFGMA EEFATKALEL KPKSYEAYYA RARAKRSSRQ FAAALEDLKE
1360 1370 1380 1390 1400
AIKLCPNNRE IQRLLMRVEE ECRQMQQQQQ QQPPPPPQQP PQELPEEETE
1410 1420 1430 1440 1450
PEPQHEDIYS VQDIFEEEYL EQDVENVSIG LQTEARPSQG LPVIQSPPSS
1460 1470 1480 1490 1500
PAHRDSAYIS SSPLGSHQVF DFRSNSSVGS PTRQGYQSTS PALSPTHQNS
1510 1520 1530 1540 1550
HYRPSPPHTS PAHQGASYRF SPPPVGGQSK EYPSPPPSPL RRGPQYRASP
1560 1570 1580 1590 1600
PAESMSVYRS QSGSPVRYQQ ETNVSQLPGR PKSPLSKMAQ RPYQMPQLPV
1610 1620 1630 1640 1650
AVPQQGLRLQ PAKAQIVRSN QPSSAVHSST VIPTGAYGQV AHSMASKYQS
1660 1670 1680 1690 1700
SQGDMGVSQS RLVYQGSIGG IVGDGRPVQH VQASLSAGAI CQHGGLTKED
1710 1720 1730 1740 1750
LPQRPSSAYR GGMRYSQTPQ IGRSQSASYY PVCHSKLDLE RSSSQLGSPD
1760 1770 1780 1790 1800
VSHLIRRPIS VNPNEIKPHP PTPRPLLHSQ SVGLRFSPSS NSISSTSNLT
1810 1820 1830 1840 1850
PTFRPSSSIQ QMEIPLKPAY DRSCDELSPV SPTQGGYPSE PTRSRTTPFM
1860 1870 1880 1890 1900
GIIDKTARTQ QYPHLHQQNR TWAVSSVDTV LSPTSPGNLP QPESFSPPSS
1910 1920 1930 1940 1950
ISNIAFYNKT NNAQNGHLLE DDYYSPHGML ANGSRGDLLE RVSQASSYPD
1960 1970 1980 1990
VKVARTLPVA QAYQDNLYRQ LSRDSRQGQT SPIKPKRPFV ESNV
Length:1,994
Mass (Da):220,263
Last modified:February 20, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA6A3B4F264CE3341
GO
Isoform 2 (identifier: A2A690-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1225-1225: I → IGCQTLPSRPR

Show »
Length:2,004
Mass (Da):221,360
Checksum:iCFBE24661B3E1555
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F6VP19F6VP19_MOUSE
Protein TANC2
Tanc2
1,137Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6VCI2F6VCI2_MOUSE
Protein TANC2
Tanc2
370Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9Q2K2E9Q2K2_MOUSE
Protein TANC2
Tanc2
117Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A140LJD2A0A140LJD2_MOUSE
Protein TANC2
Tanc2
152Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F6ZIH9F6ZIH9_MOUSE
Protein TANC2
Tanc2
12Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0335511225I → IGCQTLPSRPR in isoform 2. 1 Publication1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL596246 Genomic DNA No translation available.
AL627312 Genomic DNA No translation available.
AL645524 Genomic DNA No translation available.
AK173111 mRNA Translation: BAD32389.1
BC089352 mRNA Translation: AAH89352.1
AK162382 mRNA Translation: BAE36883.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS36357.1 [A2A690-1]

NCBI Reference Sequences

More...
RefSeqi
NP_851416.2, NM_181071.3 [A2A690-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000100330; ENSMUSP00000097904; ENSMUSG00000053580 [A2A690-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
77097

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:77097

UCSC genome browser

More...
UCSCi
uc007lxm.1 mouse [A2A690-1]
uc007lxo.1 mouse [A2A690-2]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL596246 Genomic DNA No translation available.
AL627312 Genomic DNA No translation available.
AL645524 Genomic DNA No translation available.
AK173111 mRNA Translation: BAD32389.1
BC089352 mRNA Translation: AAH89352.1
AK162382 mRNA Translation: BAE36883.1
CCDSiCCDS36357.1 [A2A690-1]
RefSeqiNP_851416.2, NM_181071.3 [A2A690-1]

3D structure databases

SMRiA2A690
ModBaseiSearch...

Protein-protein interaction databases

BioGridi218515, 4 interactors
IntActiA2A690, 2 interactors
STRINGi10090.ENSMUSP00000097904

PTM databases

GlyConnecti696
iPTMnetiA2A690
PhosphoSitePlusiA2A690
SwissPalmiA2A690

Proteomic databases

jPOSTiA2A690
MaxQBiA2A690
PaxDbiA2A690
PeptideAtlasiA2A690
PRIDEiA2A690

Genome annotation databases

EnsembliENSMUST00000100330; ENSMUSP00000097904; ENSMUSG00000053580 [A2A690-1]
GeneIDi77097
KEGGimmu:77097
UCSCiuc007lxm.1 mouse [A2A690-1]
uc007lxo.1 mouse [A2A690-2]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
26115
MGIiMGI:2444121 Tanc2

Rodent Unidentified Gene-Encoded large proteins database

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Rougei
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Phylogenomic databases

eggNOGiKOG0504 Eukaryota
COG0666 LUCA
GeneTreeiENSGT00940000156447
HOGENOMiHOG000231045
InParanoidiA2A690
OMAiACDELSP
OrthoDBi1073736at2759
PhylomeDBiA2A690
TreeFamiTF323159

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Tanc2 mouse

Protein Ontology

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PROi
PR:A2A690

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSMUSG00000053580 Expressed in 236 organ(s), highest expression level in cerebral cortex
ExpressionAtlasiA2A690 baseline and differential
GenevisibleiA2A690 MM

Family and domain databases

Gene3Di1.25.40.10, 1 hit
1.25.40.20, 3 hits
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR027417 P-loop_NTPase
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat
PfamiView protein in Pfam
PF00023 Ank, 1 hit
PF12796 Ank_2, 3 hits
PF13181 TPR_8, 2 hits
PRINTSiPR01415 ANKYRIN
SMARTiView protein in SMART
SM00248 ANK, 11 hits
SM00028 TPR, 3 hits
SUPFAMiSSF48403 SSF48403, 1 hit
SSF48452 SSF48452, 1 hit
SSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 6 hits
PS50005 TPR, 3 hits
PS50293 TPR_REGION, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTANC2_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A2A690
Secondary accession number(s): A2A683
, Q3TRZ3, Q5EBP6, Q69ZQ7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 20, 2007
Last modified: October 16, 2019
This is version 113 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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