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Protein
Submitted name:

Ectonucleotide pyrophosphatase/phosphodiesterase 7

Gene

Enpp7

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-1660662 Glycosphingolipid metabolism

Names & Taxonomyi

Protein namesi
Submitted name:
Ectonucleotide pyrophosphatase/phosphodiesterase 7Imported
Gene namesi
Name:Enpp7Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:3027917 Enpp7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_500264217322 – 425Sequence analysisAdd BLAST404

Proteomic databases

MaxQBiA2A5N7
PeptideAtlasiA2A5N7
PRIDEiA2A5N7

Expressioni

Gene expression databases

BgeeiENSMUSG00000046697 Expressed in 6 organ(s), highest expression level in colon
ExpressionAtlasiA2A5N7 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliA2A5N7
SMRiA2A5N7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG2645 Eukaryota
COG1524 LUCA
GeneTreeiENSGT00760000119157
HOGENOMiHOG000231018
HOVERGENiHBG106748
OMAiNAHPKLH

Family and domain databases

Gene3Di3.40.720.10, 1 hit
InterProiView protein in InterPro
IPR017849 Alkaline_Pase-like_a/b/a
IPR017850 Alkaline_phosphatase_core_sf
IPR029895 ENPP7
IPR002591 Phosphodiest/P_Trfase
PANTHERiPTHR10151:SF63 PTHR10151:SF63, 1 hit
PfamiView protein in Pfam
PF01663 Phosphodiest, 1 hit
SUPFAMiSSF53649 SSF53649, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A2A5N7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGHSAVLLCV ALAILPACVT GAPVQRQHKL LLVSFDGFRW NYDQDVDTPN
60 70 80 90 100
LDSMAQEGVK AQYMTPAFVT MTSPCHFTLV TGKYIENHGV VHNMFYNTTS
110 120 130 140 150
TVRLPYHATL GIQRWWDNGS IPIWITAQRQ GLKTGSFFYP GGNVTYQGEA
160 170 180 190 200
VTMSRKEGVL HNYKNETEWR GNVDTVMKWF LEEDVSLVTL YFGEPDSTGH
210 220 230 240 250
KYGPESQERK DMVKQVDRTV GYLRDSIKRH HLSDSLNLII TSDHGMTTVN
260 270 280 290 300
KKASDLVEFH KFSNFTFQDI QFELLDYGPI GMLIPKEGML EKVYSVLKDA
310 320 330 340 350
HPRLHVYKKE DFPKNFHYAN NPRITPLLMY SDLGYVIHGR VNVQFNNGEH
360 370 380 390 400
GFNNQDMDMK TIFRAVGPSF KAGLEVEPFE SVHVYELMCQ LLGIVPEPND
410 420
GNPGILRPML RSDSILLSHW TFCLP
Length:425
Mass (Da):48,405
Last modified:February 20, 2007 - v1
Checksum:i77AE72FCB6A122D9
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D3Z6V6D3Z6V6_MOUSE
Ectonucleotide pyrophosphatase/phos...
Enpp7
446Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL591544 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSMUST00000106273; ENSMUSP00000101880; ENSMUSG00000046697

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL591544 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliA2A5N7
SMRiA2A5N7
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiA2A5N7
PeptideAtlasiA2A5N7
PRIDEiA2A5N7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000106273; ENSMUSP00000101880; ENSMUSG00000046697

Organism-specific databases

MGIiMGI:3027917 Enpp7

Phylogenomic databases

eggNOGiKOG2645 Eukaryota
COG1524 LUCA
GeneTreeiENSGT00760000119157
HOGENOMiHOG000231018
HOVERGENiHBG106748
OMAiNAHPKLH

Enzyme and pathway databases

ReactomeiR-MMU-1660662 Glycosphingolipid metabolism

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000046697 Expressed in 6 organ(s), highest expression level in colon
ExpressionAtlasiA2A5N7 baseline and differential

Family and domain databases

Gene3Di3.40.720.10, 1 hit
InterProiView protein in InterPro
IPR017849 Alkaline_Pase-like_a/b/a
IPR017850 Alkaline_phosphatase_core_sf
IPR029895 ENPP7
IPR002591 Phosphodiest/P_Trfase
PANTHERiPTHR10151:SF63 PTHR10151:SF63, 1 hit
PfamiView protein in Pfam
PF01663 Phosphodiest, 1 hit
SUPFAMiSSF53649 SSF53649, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA2A5N7_MOUSE
AccessioniPrimary (citable) accession number: A2A5N7
Entry historyiIntegrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: November 7, 2018
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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