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Protein
Submitted name:

Neuralized-like protein 2

Gene

Neurl2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.SAAS annotation
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-8951664 Neddylation
UniPathwayi
UPA00143

Names & Taxonomyi

Protein namesi
Submitted name:
Neuralized-like protein 2Imported
Gene namesi
Name:Neurl2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:3043305 Neurl2

Subcellular locationi

PTM / Processingi

Proteomic databases

PRIDEiA2A5J5

Expressioni

Gene expression databases

BgeeiENSMUSG00000039873 Expressed in 129 organ(s), highest expression level in heart left ventricle
GenevisibleiA2A5J5 MM

Structurei

3D structure databases

ProteinModelPortaliA2A5J5
SMRiA2A5J5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini23 – 244NHRInterPro annotationAdd BLAST222
Domaini250 – 285SOCS boxInterPro annotationAdd BLAST36

Phylogenomic databases

eggNOGiENOG410IMDX Eukaryota
ENOG4111F7Q LUCA
GeneTreeiENSGT00730000110931
HOVERGENiHBG052607
KOiK16782
OMAiCIEQFRI
OrthoDBiEOG091G0IKU
TreeFamiTF314368

Family and domain databases

InterProiView protein in InterPro
IPR037962 Neuralized
IPR006573 NHR_dom
IPR001496 SOCS_box
IPR036036 SOCS_box-like_dom_sf
PANTHERiPTHR12429 PTHR12429, 1 hit
PfamiView protein in Pfam
PF07177 Neuralized, 1 hit
PF07525 SOCS_box, 1 hit
SMARTiView protein in SMART
SM00588 NEUZ, 1 hit
SM00969 SOCS_box, 1 hit
SUPFAMiSSF158235 SSF158235, 1 hit
PROSITEiView protein in PROSITE
PS51065 NHR, 1 hit
PS50225 SOCS, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A2A5J5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAPSEHVGL GGPRSPARPE PPPTRFHQVH GANIRMDPSG TRATRVESFA
60 70 80 90 100
HGVCFSREPL APGQVFLVEI EEKELGWCGH LRLGLTALDP ASLAAVPEFS
110 120 130 140 150
LPDLVSLGHS WVFAITRHHN RVPREGQPEA EAAVPSGPQA LLVEPYLRIE
160 170 180 190 200
QFRIPRDRLV GRSRPGLYSH LLDQLYEQNV LPPTARRSRL GVLFCPREDG
210 220 230 240 250
TADMHIIING EDMGPSARGL PAAQPLYAVV DVFASTKSVR LVQLEYGLPS
260 270 280
LQTLCRLVIQ KRVVHRLAID VLHLPKGLKD FCKYE
Length:285
Mass (Da):31,484
Last modified:February 20, 2007 - v1
Checksum:i7B22EC33F63A12EF
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9D0S4NEUL2_MOUSE
Neuralized-like protein 2
Neurl2 Ozz
285Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL591495 Genomic DNA No translation available.
RefSeqiNP_001076443.1, NM_001082974.2
UniGeneiMm.474586

Genome annotation databases

EnsembliENSMUST00000042775; ENSMUSP00000041806; ENSMUSG00000039873
GeneIDi415115
KEGGimmu:415115
UCSCiuc008nwk.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL591495 Genomic DNA No translation available.
RefSeqiNP_001076443.1, NM_001082974.2
UniGeneiMm.474586

3D structure databases

ProteinModelPortaliA2A5J5
SMRiA2A5J5
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiA2A5J5

Protocols and materials databases

DNASUi415115
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000042775; ENSMUSP00000041806; ENSMUSG00000039873
GeneIDi415115
KEGGimmu:415115
UCSCiuc008nwk.2 mouse

Organism-specific databases

CTDi140825
MGIiMGI:3043305 Neurl2

Phylogenomic databases

eggNOGiENOG410IMDX Eukaryota
ENOG4111F7Q LUCA
GeneTreeiENSGT00730000110931
HOVERGENiHBG052607
KOiK16782
OMAiCIEQFRI
OrthoDBiEOG091G0IKU
TreeFamiTF314368

Enzyme and pathway databases

UniPathwayi
UPA00143

ReactomeiR-MMU-8951664 Neddylation

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000039873 Expressed in 129 organ(s), highest expression level in heart left ventricle
GenevisibleiA2A5J5 MM

Family and domain databases

InterProiView protein in InterPro
IPR037962 Neuralized
IPR006573 NHR_dom
IPR001496 SOCS_box
IPR036036 SOCS_box-like_dom_sf
PANTHERiPTHR12429 PTHR12429, 1 hit
PfamiView protein in Pfam
PF07177 Neuralized, 1 hit
PF07525 SOCS_box, 1 hit
SMARTiView protein in SMART
SM00588 NEUZ, 1 hit
SM00969 SOCS_box, 1 hit
SUPFAMiSSF158235 SSF158235, 1 hit
PROSITEiView protein in PROSITE
PS51065 NHR, 1 hit
PS50225 SOCS, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA2A5J5_MOUSE
AccessioniPrimary (citable) accession number: A2A5J5
Entry historyiIntegrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: November 7, 2018
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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