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Protein
Submitted name:

TOX high mobility group box family member 2

Gene

Tox2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi246 – 314HMG boxPROSITE-ProRule annotationAdd BLAST69

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
TOX high mobility group box family member 2Imported
Gene namesi
Name:Tox2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:3611233 Tox2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotation

PTM / Processingi

Proteomic databases

MaxQBiA2A473
PRIDEiA2A473

Expressioni

Gene expression databases

BgeeiENSMUSG00000074607 Expressed in 213 organ(s), highest expression level in cumulus cell
ExpressionAtlasiA2A473 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliA2A473
SMRiA2A473
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini246 – 314HMG boxInterPro annotationAdd BLAST69

Phylogenomic databases

eggNOGiKOG0381 Eukaryota
COG5648 LUCA
GeneTreeiENSGT00560000076898
HOGENOMiHOG000230949
HOVERGENiHBG051183
PhylomeDBiA2A473

Family and domain databases

Gene3Di1.10.30.10, 1 hit
InterProiView protein in InterPro
IPR009071 HMG_box_dom
IPR036910 HMG_box_dom_sf
PfamiView protein in Pfam
PF00505 HMG_box, 1 hit
SMARTiView protein in SMART
SM00398 HMG, 1 hit
SUPFAMiSSF47095 SSF47095, 1 hit
PROSITEiView protein in PROSITE
PS50118 HMG_BOX_2, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

A2A473-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDVRLYPSAP AVGARPGAEP AGLAHLDYYH CGKFDGDSAY VGMSDGNPEL
60 70 80 90 100
LSTSQTYNSQ GESNEDYEIP PITPPNLPEP SLLHLGDHEA GYHSLCHGLA
110 120 130 140 150
PNGLLPAYSY QAMDLPAIMV SNMLAQDGHL LSGQLPTIQE MVHSEVAAYD
160 170 180 190 200
SGRPGPLLGR PAMLASHMSA LSQSQLISQM GIRSGIAHGS PSPPGSKSAT
210 220 230 240 250
PSPSSSTQEE ESDAHFKISG EKRPSVDPGK KAKNPKKKKK KDPNEPQKPV
260 270 280 290 300
SAYALFFRDT QAAIKGQNPS ATFGDVSKIV ASMWDSLGEE QKQAYKRKTE
310 320 330 340 350
AAKKEYLKAL AAYRASLVSK SPPDQGEAKN TQANPPAKML PPKQPMYAMP
360 370 380 390 400
GLASFLTPSD LQAFRSGASP ASLARTLGSK ALLPGLSTSP PPPSFPLSPS
410 420 430 440 450
LHQQLPLPPH AQGTLLSPPL SMSPAPQPPV LPASMALQVQ LAMSPSPPGP
460 470 480 490 500
QDFPHISDFS SGSGSRSPGP SNPSSSGDWD GSYPSGERGL GTCSLLPRDK

SLYLT
Length:505
Mass (Da):53,201
Last modified:February 5, 2008 - v1
Checksum:i413E1F9E29F00359
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9Q0B9E9Q0B9_MOUSE
TOX high mobility group box family ...
Tox2
522Annotation score:
A2A472A2A472_MOUSE
TOX high mobility group box family ...
Tox2
547Annotation score:
A2A474A2A474_MOUSE
TOX high mobility group box family ...
Tox2
124Annotation score:
F6XVL5F6XVL5_MOUSE
TOX high mobility group box family ...
Tox2
169Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL589874 Genomic DNA No translation available.
AL589876 Genomic DNA No translation available.
RefSeqiXP_006499675.1, XM_006499612.3
UniGeneiMm.207709

Genome annotation databases

EnsembliENSMUST00000109428; ENSMUSP00000105055; ENSMUSG00000074607
GeneIDi269389

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL589874 Genomic DNA No translation available.
AL589876 Genomic DNA No translation available.
RefSeqiXP_006499675.1, XM_006499612.3
UniGeneiMm.207709

3D structure databases

ProteinModelPortaliA2A473
SMRiA2A473
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiA2A473
PRIDEiA2A473

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000109428; ENSMUSP00000105055; ENSMUSG00000074607
GeneIDi269389

Organism-specific databases

CTDi84969
MGIiMGI:3611233 Tox2

Phylogenomic databases

eggNOGiKOG0381 Eukaryota
COG5648 LUCA
GeneTreeiENSGT00560000076898
HOGENOMiHOG000230949
HOVERGENiHBG051183
PhylomeDBiA2A473

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000074607 Expressed in 213 organ(s), highest expression level in cumulus cell
ExpressionAtlasiA2A473 baseline and differential

Family and domain databases

Gene3Di1.10.30.10, 1 hit
InterProiView protein in InterPro
IPR009071 HMG_box_dom
IPR036910 HMG_box_dom_sf
PfamiView protein in Pfam
PF00505 HMG_box, 1 hit
SMARTiView protein in SMART
SM00398 HMG, 1 hit
SUPFAMiSSF47095 SSF47095, 1 hit
PROSITEiView protein in PROSITE
PS50118 HMG_BOX_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA2A473_MOUSE
AccessioniPrimary (citable) accession number: A2A473
Entry historyiIntegrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: September 12, 2018
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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