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Entry version 100 (02 Jun 2021)
Sequence version 1 (05 Feb 2008)
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Protein
Submitted name:

Transient receptor potential cation channel subfamily M member 3

Gene

TRPM3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionIon channelARBA annotation
Biological processIon transport, Transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Transient receptor potential cation channel subfamily M member 3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TRPM3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 9

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:17992, TRPM3

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000083067.22

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei877 – 896HelicalSequence analysisAdd BLAST20
Transmembranei944 – 962HelicalSequence analysisAdd BLAST19
Transmembranei974 – 992HelicalSequence analysisAdd BLAST19
Transmembranei1013 – 1033HelicalSequence analysisAdd BLAST21
Transmembranei1091 – 1116HelicalSequence analysisAdd BLAST26

Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000083067

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
A2A3F7

PeptideAtlas

More...
PeptideAtlasi
A2A3F7

PRoteomics IDEntifications database

More...
PRIDEi
A2A3F7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000083067, Expressed in pigmented layer of retina and 162 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A2A3F7, baseline and differential

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini155 – 420LSDAT_eukInterPro annotationAdd BLAST266
Domaini883 – 1125Ion_transInterPro annotationAdd BLAST243
Domaini1219 – 1274TRPM_tetraInterPro annotationAdd BLAST56

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 63DisorderedSequence analysisAdd BLAST63
Regioni1438 – 1457DisorderedSequence analysisAdd BLAST20
Regioni1590 – 1711DisorderedSequence analysisAdd BLAST122

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1222 – 1242Sequence analysisAdd BLAST21
Coiled coili1260 – 1280Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 40Basic and acidic residuesSequence analysisAdd BLAST40
Compositional biasi42 – 63Polar residuesSequence analysisAdd BLAST22
Compositional biasi1438 – 1453Polar residuesSequence analysisAdd BLAST16
Compositional biasi1590 – 1609Basic and acidic residuesSequence analysisAdd BLAST20
Compositional biasi1615 – 1637Polar residuesSequence analysisAdd BLAST23

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisARBA annotation

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000157366

Identification of Orthologs from Complete Genome Data

More...
OMAi
PAEHPFY

Database of Orthologous Groups

More...
OrthoDBi
738147at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.5.1010, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR005821, Ion_trans_dom
IPR029583, TRPM3
IPR041491, TRPM_SLOG
IPR032415, TRPM_tetra
IPR037162, TRPM_tetra_sf

The PANTHER Classification System

More...
PANTHERi
PTHR13800:SF7, PTHR13800:SF7, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00520, Ion_trans, 1 hit
PF18139, LSDAT_euk, 1 hit
PF16519, TRPM_tetra, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 11 potential isoforms that are computationally mapped.Show allAlign All

A2A3F7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGKKWRDAAE MERGCSDRED NAESRRRSRS ASRGRFAESW KRLSSKQGST
60 70 80 90 100
KRSGLPSQQT PAQKSWIERA FYKRECVHII PSTKDPHRCC CGRLIGQHVG
110 120 130 140 150
LTPSISVLQN EKNESRLSRN DIQSEKWSIS KHTQLSPTDA FGTIEFQGGG
160 170 180 190 200
HSNKAMYVRV SFDTKPDLLL HLMTKEWQLE LPKLLISVHG GLQNFELQPK
210 220 230 240 250
LKQVFGKGLI KAAMTTGAWI FTGGVNTGVI RHVGDALKDH ASKSRGKICT
260 270 280 290 300
IGIAPWGIVE NQEDLIGRDV VRPYQTMSNP MSKLTVLNSM HSHFILADNG
310 320 330 340 350
TTGKYGAEVK LRRQLEKHIS LQKINTRIGQ GVPVVALIVE GGPNVISIVL
360 370 380 390 400
EYLRDTPPVP VVVCDGSGRA SDILAFGHKY SEEGGLINES LRDQLLVTIQ
410 420 430 440 450
KTFTYTRTQA QHLFIILMEC MKKKELITVF RMGSEGHQDI DLAILTALLK
460 470 480 490 500
GANASAPDQL SLALAWNRVD IARSQIFIYG QQWPVGSLEQ AMLDALVLDR
510 520 530 540 550
VDFVKLLIEN GVSMHRFLTI SRLEELYNTR HGPSNTLYHL VRDVKKREYP
560 570 580 590 600
GFGWIYFKGN LPPDYRISLI DIGLVIEYLM GGAYRCNYTR KRFRTLYHNL
610 620 630 640 650
FGPKRDDIPL RRGRKTTKKR EEEVDIDLDD PEINHFPFPF HELMVWAVLM
660 670 680 690 700
KRQKMALFFW QHGEEAMAKA LVACKLCKAM AHEASENDMV DDISQELNHN
710 720 730 740 750
SRDFGQLAVE LLDQSYKQDE QLAMKLLTYE LKNWSNATCL QLAVAAKHRD
760 770 780 790 800
FIAHTCSQML LTDMWMGRLR MRKNSGLKVI LGILLPPSIL SLEFKNKDDM
810 820 830 840 850
PYMSQAQEIH LQEKEAEEPE KPTKEKEEED MELTAMLGRN NGESSRKKDE
860 870 880 890 900
EEVQSKHRLI PLGRKIYEFY NAPIVKFWFY TLAYIGYLML FNYIVLVKME
910 920 930 940 950
RWPSTQEWIV ISYIFTLGIE KMREILMSEP GKLLQKVKVW LQEYWNVTDL
960 970 980 990 1000
IAILLFSVGM ILRLQDQPFR SDGRVIYCVN IIYWYIRLLD IFGVNKYLGP
1010 1020 1030 1040 1050
YVMMIGKMMI DMMYFVIIML VVLMSFGVAR QAILFPNEEP SWKLAKNIFY
1060 1070 1080 1090 1100
MPYWMIYGEV FADQIDPPCG QNETREDGKI IQLPPCKTGA WIVPAIMACY
1110 1120 1130 1140 1150
LLVANILLVN LLIAVFNNTF FEVKSISNQV WKFQRYQLIM TFHERPVLPP
1160 1170 1180 1190 1200
PLIIFSHMTM IFQHLCCRWR KHESDPDERD YGLKLFITDD ELKKVHDFEE
1210 1220 1230 1240 1250
QCIEEYFREK DDRFNSSNDE RIRVTSERVE NMSMRLEEVN EREHSMKASL
1260 1270 1280 1290 1300
QTVDIRLAQL EDLIGRMATA LERLTGLERA ESNKIRSRTS SDCTDAAYIV
1310 1320 1330 1340 1350
RQSSFNSQEG NTFKLQESID PAGEETMSPT SPTLMPRMRS HSFYSVNMKD
1360 1370 1380 1390 1400
KGGIEKLESI FKERSLSLHR ATSSHSVAKE PKAPAAPANT LAIVPDSRRP
1410 1420 1430 1440 1450
SSCIDIYVSA MDELHCDIDP LDNSVNILGL GEPSFSTPVP STAPSSSAYA
1460 1470 1480 1490 1500
TLAPTDRPPS RSIDFEDITS MDTRSFSSDY THLPECQNPW DSEPPMYHTI
1510 1520 1530 1540 1550
ERSKSSRYLA TTPFLLEEAP IVKSHSFMFS PSRSYYANFG VPVKTAEYTS
1560 1570 1580 1590 1600
ITDCIDTRCV NAPQAIADRA AFPGGLGDKV EDLTCCHPER EAELSHPSSD
1610 1620 1630 1640 1650
SEENEAKGRR ATIAISSQEG DNSERTLSNN ITVPKIERAN SYSAEEPSAP
1660 1670 1680 1690 1700
YAHTRKSFSI SDKLDRQRNT ASLRNPFQRS KSSKPEGRGD SLSMRRLSRT
1710
SAFQSFESKH N
Length:1,711
Mass (Da):195,285
Last modified:February 5, 2008 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8F60191D13A65686
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 11 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9HCF6TRPM3_HUMAN
Transient receptor potential cation...
TRPM3 KIAA1616, LTRPC3
1,732Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PBI7E9PBI7_HUMAN
Transient receptor potential cation...
TRPM3
1,579Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G5E9G1G5E9G1_HUMAN
Transient receptor potential cation...
TRPM3 hCG_2042991
1,566Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7BYP1H7BYP1_HUMAN
Transient receptor potential cation...
TRPM3 hCG_2042991
1,556Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A2A3F4A2A3F4_HUMAN
Transient receptor potential cation...
TRPM3
1,569Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A2A3F3A2A3F3_HUMAN
Transient receptor potential cation...
TRPM3
1,566Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A7I2V4E8A0A7I2V4E8_HUMAN
Transient receptor potential cation...
TRPM3
1,690Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q504Y1Q504Y1_HUMAN
TRPM3 protein
TRPM3
323Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0Y3D4H0Y3D4_HUMAN
Transient receptor potential cation...
TRPM3
123Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q4VXD4Q4VXD4_HUMAN
Transient receptor potential cation...
TRPM3
275Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There is more potential isoformShow all

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL159990 Genomic DNA No translation available.
AL160273 Genomic DNA No translation available.
AL161913 Genomic DNA No translation available.
AL356318 Genomic DNA No translation available.
AL358786 Genomic DNA No translation available.
AL391819 Genomic DNA No translation available.
AL442645 Genomic DNA No translation available.
AL592438 Genomic DNA No translation available.
KF458923 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
XP_011517344.1, XM_011519042.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000357533; ENSP00000350140; ENSG00000083067

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
80036

UCSC genome browser

More...
UCSCi
uc064trd.1, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL159990 Genomic DNA No translation available.
AL160273 Genomic DNA No translation available.
AL161913 Genomic DNA No translation available.
AL356318 Genomic DNA No translation available.
AL358786 Genomic DNA No translation available.
AL391819 Genomic DNA No translation available.
AL442645 Genomic DNA No translation available.
AL592438 Genomic DNA No translation available.
KF458923 Genomic DNA No translation available.
RefSeqiXP_011517344.1, XM_011519042.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

MaxQBiA2A3F7
PeptideAtlasiA2A3F7
PRIDEiA2A3F7

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
12418, 158 antibodies

The DNASU plasmid repository

More...
DNASUi
80036

Genome annotation databases

EnsembliENST00000357533; ENSP00000350140; ENSG00000083067
GeneIDi80036
UCSCiuc064trd.1, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
80036
HGNCiHGNC:17992, TRPM3
OpenTargetsiENSG00000083067
VEuPathDBiHostDB:ENSG00000083067.22

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

GeneTreeiENSGT00940000157366
OMAiPAEHPFY
OrthoDBi738147at2759

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
80036, 3 hits in 989 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
TRPM3, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
80036

Gene expression databases

BgeeiENSG00000083067, Expressed in pigmented layer of retina and 162 other tissues
ExpressionAtlasiA2A3F7, baseline and differential

Family and domain databases

Gene3Di1.20.5.1010, 1 hit
InterProiView protein in InterPro
IPR005821, Ion_trans_dom
IPR029583, TRPM3
IPR041491, TRPM_SLOG
IPR032415, TRPM_tetra
IPR037162, TRPM_tetra_sf
PANTHERiPTHR13800:SF7, PTHR13800:SF7, 1 hit
PfamiView protein in Pfam
PF00520, Ion_trans, 1 hit
PF18139, LSDAT_euk, 1 hit
PF16519, TRPM_tetra, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA2A3F7_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A2A3F7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: June 2, 2021
This is version 100 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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