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Protein

Palmitoyltransferase

Gene

CG17287

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.UniRule annotation

GO - Molecular functioni

  • protein-cysteine S-palmitoyltransferase activity Source: FlyBase

GO - Biological processi

  • protein palmitoylation Source: FlyBase

Keywordsi

Molecular functionAcyltransferaseUniRule annotationImported, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
PalmitoyltransferaseUniRule annotation (EC:2.3.1.225UniRule annotation)
Gene namesi
ORF Names:CG17287Imported, Dmel_CG17287Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2R

Organism-specific databases

FlyBaseiFBgn0034202 CG17287

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei18 – 35HelicalUniRule annotationAdd BLAST18
Transmembranei47 – 69HelicalUniRule annotationAdd BLAST23
Transmembranei169 – 191HelicalUniRule annotationAdd BLAST23
Transmembranei211 – 233HelicalUniRule annotationAdd BLAST23

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiA1ZAR2
PRIDEiA1ZAR2

Expressioni

Gene expression databases

BgeeiFBgn0034202
ExpressionAtlasiA1ZAR2 differential
GenevisibleiA1ZAR2 DM

Interactioni

Protein-protein interaction databases

IntActiA1ZAR2, 1 interactor
STRINGi7227.FBpp0086152

Structurei

3D structure databases

SMRiA1ZAR2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini125 – 244DHHCInterPro annotationAdd BLAST120

Domaini

The DHHC domain is required for palmitoyltransferase activity.UniRule annotation

Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG1315 Eukaryota
COG5273 LUCA
InParanoidiA1ZAR2
KOiK20028
OMAiRYCKTCW
OrthoDBiEOG091G0AXR
PhylomeDBiA1ZAR2

Family and domain databases

InterProiView protein in InterPro
IPR001594 Palmitoyltrfase_DHHC
PfamiView protein in Pfam
PF01529 DHHC, 1 hit

Sequencei

Sequence statusi: Complete.

A1ZAR2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCPIGEGHRR VPCCAVRWLP ALIILGFLVW SYHVFVYQIC IKKVSDYLTI
60 70 80 90 100
GLLLFFYHLL LFMFLWTWFR CIFVAPVRIP DQWKISPEDV DKLKRNDGIE
110 120 130 140 150
GASRVLNYAA RNLPIATCTI DGLVRYCKTC WIIKPDRAHH CRTCHMCVLK
160 170 180 190 200
MDHHCPWIVN CVHFHNFKYF ILFLFYAEVY CFYLFCVMVY DLYLICGFEV
210 220 230 240 250
TALKNQHSWN ILQYLVCILF NIFTVIMYTV SLLNVSRNRT TMESAYATYF
260 270 280 290 300
LLGGKNNNGF NLGYFVNFRD LYGDKWYLWP FPIFSSRGDG FSFPLAHDRL
310 320 330
KEVRTGNQKK DNQPTRTQMY KENMNRILGI HQPPFNEE
Length:338
Mass (Da):40,056
Last modified:February 6, 2007 - v1
Checksum:i7C94824B6F201E07
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA Translation: AAF57887.1
RefSeqiNP_611197.1, NM_137353.2
UniGeneiDm.28156

Genome annotation databases

EnsemblMetazoaiFBtr0087000; FBpp0086152; FBgn0034202
GeneIDi36939
KEGGidme:Dmel_CG17287
UCSCiCG17287-RA d. melanogaster

Similar proteinsi

Entry informationi

Entry nameiA1ZAR2_DROME
AccessioniPrimary (citable) accession number: A1ZAR2
Entry historyiIntegrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: July 18, 2018
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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