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Entry version 98 (03 Jul 2019)
Sequence version 1 (06 Feb 2007)
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Protein
Submitted name:

Su(Var)2-HP2, isoform A

Gene

Su(var)2-HP2

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • DNA binding Source: FlyBase

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Su(Var)2-HP2, isoform AImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Su(var)2-HP2Imported
Synonyms:Dmel\CG12864Imported, HP2Imported, Hp2Imported, SU(VAR)2-HP2Imported
ORF Names:CG12864Imported, Dmel_CG12864Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2R

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0026427 Su(var)2-HP2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
A1Z9S6

PRoteomics IDEntifications database

More...
PRIDEi
A1Z9S6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
FBgn0026427 Expressed in 28 organ(s), highest expression level in egg cell

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A1Z9S6 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
A1Z9S6 DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
A1Z9S6, 9 interactors

STRING: functional protein association networks

More...
STRINGi
7227.FBpp0086630

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni18 – 44DisorderedSequence analysisAdd BLAST27
Regioni62 – 394DisorderedSequence analysisAdd BLAST333
Regioni421 – 568DisorderedSequence analysisAdd BLAST148
Regioni584 – 687DisorderedSequence analysisAdd BLAST104
Regioni730 – 751DisorderedSequence analysisAdd BLAST22
Regioni763 – 948DisorderedSequence analysisAdd BLAST186
Regioni961 – 1028DisorderedSequence analysisAdd BLAST68
Regioni1047 – 1419DisorderedSequence analysisAdd BLAST373
Regioni1482 – 1824DisorderedSequence analysisAdd BLAST343
Regioni1836 – 1954DisorderedSequence analysisAdd BLAST119
Regioni1966 – 2000DisorderedSequence analysisAdd BLAST35
Regioni2100 – 2243DisorderedSequence analysisAdd BLAST144
Regioni2265 – 2425DisorderedSequence analysisAdd BLAST161
Regioni2480 – 2539DisorderedSequence analysisAdd BLAST60
Regioni2789 – 2828DisorderedSequence analysisAdd BLAST40
Regioni2847 – 2881DisorderedSequence analysisAdd BLAST35
Regioni3131 – 3172DisorderedSequence analysisAdd BLAST42

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi20 – 44PolarSequence analysisAdd BLAST25
Compositional biasi62 – 84PolyampholyteSequence analysisAdd BLAST23
Compositional biasi85 – 103PolarSequence analysisAdd BLAST19
Compositional biasi104 – 127PolyampholyteSequence analysisAdd BLAST24
Compositional biasi134 – 211PolarSequence analysisAdd BLAST78
Compositional biasi238 – 262AcidicSequence analysisAdd BLAST25
Compositional biasi265 – 328PolarSequence analysisAdd BLAST64
Compositional biasi357 – 376PolyampholyteSequence analysisAdd BLAST20
Compositional biasi377 – 394PolarSequence analysisAdd BLAST18
Compositional biasi421 – 436PolyampholyteSequence analysisAdd BLAST16
Compositional biasi438 – 458PolarSequence analysisAdd BLAST21
Compositional biasi497 – 539PolyampholyteSequence analysisAdd BLAST43
Compositional biasi540 – 564PolarSequence analysisAdd BLAST25
Compositional biasi584 – 600PolarSequence analysisAdd BLAST17
Compositional biasi601 – 673PolyampholyteSequence analysisAdd BLAST73
Compositional biasi826 – 841PolyampholyteSequence analysisAdd BLAST16
Compositional biasi845 – 875PolarSequence analysisAdd BLAST31
Compositional biasi891 – 914PolyampholyteSequence analysisAdd BLAST24
Compositional biasi930 – 948PolyampholyteSequence analysisAdd BLAST19
Compositional biasi961 – 977PolyampholyteSequence analysisAdd BLAST17
Compositional biasi978 – 997PolarSequence analysisAdd BLAST20
Compositional biasi1014 – 1028PolyampholyteSequence analysisAdd BLAST15
Compositional biasi1047 – 1065PolyampholyteSequence analysisAdd BLAST19
Compositional biasi1104 – 1128PolyampholyteSequence analysisAdd BLAST25
Compositional biasi1134 – 1152PolarSequence analysisAdd BLAST19
Compositional biasi1173 – 1188PolarSequence analysisAdd BLAST16
Compositional biasi1189 – 1205PolyampholyteSequence analysisAdd BLAST17
Compositional biasi1215 – 1261PolarSequence analysisAdd BLAST47
Compositional biasi1283 – 1345PolyampholyteSequence analysisAdd BLAST63
Compositional biasi1370 – 1391PolarSequence analysisAdd BLAST22
Compositional biasi1392 – 1419PolyampholyteSequence analysisAdd BLAST28
Compositional biasi1498 – 1519PolarSequence analysisAdd BLAST22
Compositional biasi1533 – 1574PolarSequence analysisAdd BLAST42
Compositional biasi1575 – 1589PolyampholyteSequence analysisAdd BLAST15
Compositional biasi1590 – 1610PolarSequence analysisAdd BLAST21
Compositional biasi1626 – 1640PolarSequence analysisAdd BLAST15
Compositional biasi1714 – 1733PolyampholyteSequence analysisAdd BLAST20
Compositional biasi1739 – 1758PolarSequence analysisAdd BLAST20
Compositional biasi1765 – 1781PolarSequence analysisAdd BLAST17
Compositional biasi1782 – 1815PolyampholyteSequence analysisAdd BLAST34
Compositional biasi1859 – 1883PolarSequence analysisAdd BLAST25
Compositional biasi1884 – 1947PolyampholyteSequence analysisAdd BLAST64
Compositional biasi1966 – 1989PolarSequence analysisAdd BLAST24
Compositional biasi2100 – 2114PolarSequence analysisAdd BLAST15
Compositional biasi2115 – 2141PolyampholyteSequence analysisAdd BLAST27
Compositional biasi2191 – 2210PolyampholyteSequence analysisAdd BLAST20
Compositional biasi2303 – 2318PolarSequence analysisAdd BLAST16
Compositional biasi2333 – 2361PolarSequence analysisAdd BLAST29
Compositional biasi2362 – 2381PolyampholyteSequence analysisAdd BLAST20
Compositional biasi2394 – 2425PolyampholyteSequence analysisAdd BLAST32
Compositional biasi2492 – 2539PolarSequence analysisAdd BLAST48
Compositional biasi2801 – 2828PolarSequence analysisAdd BLAST28
Compositional biasi2854 – 2881PolarSequence analysisAdd BLAST28
Compositional biasi3144 – 3172PolarSequence analysisAdd BLAST29

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1181 Eukaryota
ENOG4111M3T LUCA

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
A1Z9S6

Identification of Orthologs from Complete Genome Data

More...
OMAi
PPIYKKQ

Database of Orthologous Groups

More...
OrthoDBi
30577at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
A1Z9S6

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A1Z9S6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEDIEYLDEY KDLVLPGIKS SAPTASSAGV PRQRRISSDS SNSSSIDADI
60 70 80 90 100
FQKLFHGKYL DDELLKEGSG SKSQDRRRRP PSPSSSDESN DALEALFCGK
110 120 130 140 150
SSQSKLSKRR ERYESFDSVD DLGEALMRPS HRLTVPKPST SQAGSKKSQD
160 170 180 190 200
AAPHRSISNS SSSNIAMSSG QTYACPKNKK TNSVANKTAV SANGDKWASG
210 220 230 240 250
KNKTVTIVKP QKTDLRPSRL EPKTDPLNLG DLYGDSDSDS SYEYESDFYG
260 270 280 290 300
DQDSDEEDEP VIDISTDTSR TTSVADTVTP VVSDDEGQEP QSELNQRHAN
310 320 330 340 350
DQESFLSSTY ERLQSYLSNL SSAEPPPIYK KQNSARKSRS NEKKPSSSQQ
360 370 380 390 400
VKHANEQSAA SDKEANKKER DLEPPEASSS AKSSASKASG SRKLYDVANN
410 420 430 440 450
ATLEAVERMS LDLAEQIMEI DVERSYEFEK RSASKSRSLS RSKIPADSST
460 470 480 490 500
SQLGHVRKLT YSSERLDQPE PLGTQLRRSK SESLPKRGRP RGQKQRKNRG
510 520 530 540 550
ATMEEKSANC RDGEGEPVKR KRGRPRKIIP KEEAKTAETE NTIESLNTNV
560 570 580 590 600
PLSIDTSKEN PETETVNLEV PIKQDELVSD LDNAKELTGS TNLPQDDIEM
610 620 630 640 650
ASNHQETDLK CAPDRVALDK SESTPKVEEE QLCKVDTPSD TALDESKVSE
660 670 680 690 700
SAKNHIELED KDKDKEETQK ESPNGNSKET NENSVIVTNE VELPAKKAEA
710 720 730 740 750
KAEAGNIVEE SDSQLAEDFK LAEEILAAEV GKGVEANEVS VTSVQGEQNP
760 770 780 790 800
VIEIVKELEQ ETISEVVPAQ NDQSSVEDQT LADKENPVEK PSPVKAPSSS
810 820 830 840 850
KDEPPAEENL PAPDQDPIEQ QKTPVAKNQQ HDKEHNEAPK AESLSVSDIP
860 870 880 890 900
SSSVTPSKKR NHSSPANTPK KSKEIEALQS SVPRRALRSD KATPQNLRES
910 920 930 940 950
RSKRTLKTEL TLLMDDTMRR SSPRLGRSPA ESHSSHERSP MEKKVTVSKL
960 970 980 990 1000
AKDLITIDKE KEIELKSLPD ASETKDVKIT KTTTASDTSI LTDENPSSSK
1010 1020 1030 1040 1050
TEMKKLKGKP LKAKKMSRTS ETEVKKAIAD SNEDIPSIFS IKCVEEHLTS
1060 1070 1080 1090 1100
SESEQKDEKE ELLCPKPQID CTNTDLEQST AIETDTEQVE EKRSNRRKSR
1110 1120 1130 1140 1150
RIRNEKFKTE TDTLSDHLDA KKAENASLEI SMRPKCTLET QQSDPVTAKN
1160 1170 1180 1190 1200
KRNSGRLSRK EKSVINAAKS EKDKSPSAIS QSTERKQLLN ENPSKKDKKT
1210 1220 1230 1240 1250
EQSGNKKEAV VGPLDKTETS SSTNIIDKKS NESFDSAMQP SDRLNQKESA
1260 1270 1280 1290 1300
FTKLSSISSP KKIMKDQDKD LDALSKGGDS NPTIRDTGED SRQTDKKHQE
1310 1320 1330 1340 1350
NDTKHEEEDS SKLKANIDET KSSSEKDAEP ISKDSSQDSA KPRLSKPKSR
1360 1370 1380 1390 1400
NKRKKNEKKP NDSIAESDIE GGFQVNTETV QATCSTPSES NKKDMVKSDE
1410 1420 1430 1440 1450
TNEEPNLSET EIGRIRKRGQ AFHIENPKDD LHITPQNENQ SIAGVNFEKQ
1460 1470 1480 1490 1500
VPLPESVESD TPIMKIPTKT YLMCTKNKTS LLSASEDPDI VLEPQKLITT
1510 1520 1530 1540 1550
SKGDSNPDLD NANNLETSST QDPKEHEFSD QTFTDNSDII PSCTKKSQIV
1560 1570 1580 1590 1600
FPTTPTKSSD QTKNSFITPN RSPKSKRNVS KEAKRLDNSF EESQNAASES
1610 1620 1630 1640 1650
SASKVQKELR TPTASCRKLR VLIKRTPTSS LPTNSRKSIF KKTPAKSKRL
1660 1670 1680 1690 1700
TKILESMEKT PSREPSVSLG EVNPDSDPVA AESVAVLHES DRDLESNEIP
1710 1720 1730 1740 1750
NEEVFEDTEE ASAEDTDNKL KKKEDDHELE VNDICAASKN PITDDSTKDA
1760 1770 1780 1790 1800
SSNKSTDSDV LQETKDELSN SLINATQGED TPIKELTEEE VPNNKTVEDE
1810 1820 1830 1840 1850
SKKQEILKDL EPDNAALEED TASTAKAAEE MDLYIKEKSN VKSVLAEPET
1860 1870 1880 1890 1900
DVTDDEELAQ SPIPNSSETT SVTDDPEPST SSVVKRSLRK READSSQPDE
1910 1920 1930 1940 1950
AAKRKQRQDV EKSLTGKKEQ VKPARRRQLA EVEERPSLKR SKTESEAKST
1960 1970 1980 1990 2000
VQGKYISIIG NETIMSSTTA PIRETNREAA STSPSARKSA VQEAKHVETT
2010 2020 2030 2040 2050
KHIILGPPGK KLLHSDSPAA EVKKPMVQTL LSSTLSLQKP STLDDGSPLK
2060 2070 2080 2090 2100
IRKSLKKSIA DENIDGDQSI FSSSSVLNKN TSVVAPRKVN ISVSLLQSKD
2110 2120 2130 2140 2150
TQVETAASSS ETPILTKKEK LKTQKSTKKP EGNKKTESKK KSLVQGPQMK
2160 2170 2180 2190 2200
TQKSEEAVSG PKILNKYLKS ETESSRKTVS TVTGRKQIGQ LEVLKKPESR
2210 2220 2230 2240 2250
KSEESLVEAI SRKKQSQVQR LSKIDGRKSE GTSLPQPDVS KSETALKAAL
2260 2270 2280 2290 2300
PKETEFPVQD AEIEKMSKGR GHQNAVKNTK TEQPKSKPKT EVRSLQAEAA
2310 2320 2330 2340 2350
TELMDSMDSQ SDVSDIRATF PESQGIFNVP GHMTRAISSN RSLAPTPTPM
2360 2370 2380 2390 2400
SDSQRNASKE RFTPVSDQKK PIRESQTLSK RRARGGRNQP LVSKRKAGEA
2410 2420 2430 2440 2450
EDGTAVINPK RPREMDEEDH PQQNDHVQES AFAAFPVKIT AASSVIPQVV
2460 2470 2480 2490 2500
RSTGNTVPQN ISPRKLCVKI NRRPYNKWLR STQERNEEQE GSRNVTSLPL
2510 2520 2530 2540 2550
LGETSETDSA AESMSESILQ SQVQSEPAIQ PLPASQPDSC TLQASDLRIR
2560 2570 2580 2590 2600
ESSAQLAPIA AYDSPAANDS STSPALDIAP ESAQTAKATL NTALCPSTEK
2610 2620 2630 2640 2650
HLPDEPTLLE SSKKVAEPQK LQTFQAKCLP VPIPEVKSEP EDIMDEHSPN
2660 2670 2680 2690 2700
EPMPMVAAAP ATPQPHAITE DAGPDTIQVN TLGVSTSSRP LELHSIPSAS
2710 2720 2730 2740 2750
DPDGNPNAIG QTKMYSFLYP KRYKQSYDDV GLDFCCPNLD GPMRAIDFTR
2760 2770 2780 2790 2800
LHSKAEVPVL EIPQFLVITT KFISKADKNM PSKVRAKLEL LDKSKERDSS
2810 2820 2830 2840 2850
KLTPTATTPT ADPTGPSSFS PAPASVGPAT QPFPSIIQNL LSAPLPDPGL
2860 2870 2880 2890 2900
FNHPTTVDPS TSTPVVSGSS SSTTISADLD SLSKQLPRGT KLIKKSVQQV
2910 2920 2930 2940 2950
ATNPSLAGTS MVINASPSFI QLPPICPNDK QRVELQARVQ MFDLVLQTLS
2960 2970 2980 2990 3000
RRAANLSVAE RQRTIEEIVR TSSLMAIDVD VGTKLLENYV HYLNKATSTM
3010 3020 3030 3040 3050
TPLTPAQINS SLGASTSSTL SKSIATSDIP QQGKKISADH AQQRSSLPAT
3060 3070 3080 3090 3100
IPLYDGGRNT LGFPYSCSKS TAGRKSSYVA TSTPVKASTS QAAAAAALGN
3110 3120 3130 3140 3150
AQPRSTLGIP KSVREDASQF VNLNTTVCMP APRTNAKKKP GTSGPLKSMN
3160 3170 3180 3190 3200
SSPAVQKPAL CKQQTAPART LSKSTVSSVA RAKSTGSLSA VLGETPADEF
3210 3220 3230 3240 3250
VSPAGMSLST TGNPNVFIIN HAVQSEESIL PDSNSSVGHM ETTVIKGELD

DSAEIII
Length:3,257
Mass (Da):355,974
Last modified:February 6, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7E9212C20A40810C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A1Z9S5A1Z9S5_DROME
RE12383p
Su(var)2-HP2 Dmel\CG12864, HP2, Hp2, SU(VAR)2-HP2, Su(var)2-HP2-RB
1,633Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AE013599 Genomic DNA Translation: AAF58230.1

NCBI Reference Sequences

More...
RefSeqi
NP_610972.2, NM_137128.4

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0087501; FBpp0086630; FBgn0026427

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
36621

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dme:Dmel_CG12864

UCSC genome browser

More...
UCSCi
CG12864-RA d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA Translation: AAF58230.1
RefSeqiNP_610972.2, NM_137128.4

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

IntActiA1Z9S6, 9 interactors
STRINGi7227.FBpp0086630

Proteomic databases

PaxDbiA1Z9S6
PRIDEiA1Z9S6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0087501; FBpp0086630; FBgn0026427
GeneIDi36621
KEGGidme:Dmel_CG12864
UCSCiCG12864-RA d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
36621
FlyBaseiFBgn0026427 Su(var)2-HP2

Phylogenomic databases

eggNOGiKOG1181 Eukaryota
ENOG4111M3T LUCA
InParanoidiA1Z9S6
OMAiPPIYKKQ
OrthoDBi30577at2759
PhylomeDBiA1Z9S6

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
36621

Gene expression databases

BgeeiFBgn0026427 Expressed in 28 organ(s), highest expression level in egg cell
ExpressionAtlasiA1Z9S6 baseline and differential
GenevisibleiA1Z9S6 DM

Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA1Z9S6_DROME
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A1Z9S6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: July 3, 2019
This is version 98 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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