Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Due to a server migration, the UniProt 'ID mapping', 'Peptide search' and 'community bibliography submission' tools will not be available on the 19th April 2021 during the morning (EST).

UniProtKB - A1Z9J3 (A1Z9J3_DROME)

Entry version 135 (07 Apr 2021)
Sequence version 1 (06 Feb 2007)
Previous versions | rss
Add a publicationFeedback
Protein
Submitted name:

Short stop, isoform H

Gene

shot

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) of the calcium-binding region(s) within the protein. One common calcium-binding motif is the EF-hand, but other calcium-binding motifs also exist.<p><a href='/help/ca_bind' target='_top'>More...</a></p>Calcium bindingi8420 – 8431PROSITE-ProRule annotationAdd BLAST12

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandCalciumPROSITE-ProRule annotation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-DME-264870, Caspase-mediated cleavage of cytoskeletal proteins
R-DME-351906, Apoptotic cleavage of cell adhesion proteins
R-DME-446107, Type I hemidesmosome assembly
R-DME-6798695, Neutrophil degranulation
R-DME-6809371, Formation of the cornified envelope

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Short stop, isoform HImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:shotImported
Synonyms:4Imported, 42Imported, CG18637Imported, Dmel\CG18076Imported, GrvImported, grvImported, KakImported, kakImported, kakapoImported, kakpImported, kopImported, l(2)CA4Imported, l(2)k03010Imported, l(2)k04204Imported, l(2)k05434Imported, l(2)k05821Imported, l(2)k10821Imported, l(2)k15606Imported, shortstopImported, ShotImported, Su(Mir)1Imported
ORF Names:CG18076Imported, Dmel_CG18076Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila melanogaster (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7227 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000803 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2R

Organism-specific databases

Drosophila genome database

More...FlyBasei		FBgn0013733, shot

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, CytoskeletonARBA annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Keywords - PTMi

PhosphoproteinARBA annotation

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		A1Z9J3

PRoteomics IDEntifications database

More...PRIDEi		A1Z9J3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		FBgn0013733, Expressed in mouthpart (Drosophila) and 42 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		A1Z9J3, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		A1Z9J3, DM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

Protein interaction database and analysis system

More...IntActi		A1Z9J3, 44 interactors

Molecular INTeraction database

More...MINTi		A1Z9J3

STRING: functional protein association networks

More...STRINGi		7227.FBpp0086747

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		A1Z9J3

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini222 – 327Calponin-homology (CH)InterPro annotationAdd BLAST106
Domaini873 – 931SH3InterPro annotationAdd BLAST59
Domaini8371 – 8406EF-handInterPro annotationAdd BLAST36
Domaini8407 – 8442EF-handInterPro annotationAdd BLAST36
Domaini8447 – 8519GARInterPro annotationAdd BLAST73

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 45DisorderedSequence analysisAdd BLAST45
Regioni2808 – 2830DisorderedSequence analysisAdd BLAST23
Regioni2855 – 2884DisorderedSequence analysisAdd BLAST30
Regioni2923 – 2959DisorderedSequence analysisAdd BLAST37
Regioni3070 – 3201DisorderedSequence analysisAdd BLAST132
Regioni3248 – 3380DisorderedSequence analysisAdd BLAST133
Regioni5591 – 5655DisorderedSequence analysisAdd BLAST65
Regioni8238 – 8311DisorderedSequence analysisAdd BLAST74
Regioni8546 – 8579DisorderedSequence analysisAdd BLAST34
Regioni8591 – 8805DisorderedSequence analysisAdd BLAST215

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili438 – 482Sequence analysisAdd BLAST45
Coiled coili502 – 522Sequence analysisAdd BLAST21
Coiled coili659 – 679Sequence analysisAdd BLAST21
Coiled coili838 – 858Sequence analysisAdd BLAST21
Coiled coili1013 – 1040Sequence analysisAdd BLAST28
Coiled coili1153 – 1173Sequence analysisAdd BLAST21
Coiled coili1365 – 1385Sequence analysisAdd BLAST21
Coiled coili1571 – 1591Sequence analysisAdd BLAST21
Coiled coili4976 – 4996Sequence analysisAdd BLAST21
Coiled coili5072 – 5092Sequence analysisAdd BLAST21
Coiled coili5162 – 5182Sequence analysisAdd BLAST21
Coiled coili5270 – 5297Sequence analysisAdd BLAST28
Coiled coili5337 – 5357Sequence analysisAdd BLAST21
Coiled coili5409 – 5436Sequence analysisAdd BLAST28
Coiled coili5511 – 5531Sequence analysisAdd BLAST21
Coiled coili5676 – 5707Sequence analysisAdd BLAST32
Coiled coili5719 – 5739Sequence analysisAdd BLAST21
Coiled coili5763 – 5783Sequence analysisAdd BLAST21
Coiled coili5975 – 6002Sequence analysisAdd BLAST28
Coiled coili6193 – 6213Sequence analysisAdd BLAST21
Coiled coili6217 – 6244Sequence analysisAdd BLAST28
Coiled coili6299 – 6319Sequence analysisAdd BLAST21
Coiled coili6334 – 6354Sequence analysisAdd BLAST21
Coiled coili6375 – 6402Sequence analysisAdd BLAST28
Coiled coili6415 – 6435Sequence analysisAdd BLAST21
Coiled coili6519 – 6546Sequence analysisAdd BLAST28
Coiled coili6839 – 6866Sequence analysisAdd BLAST28
Coiled coili6963 – 6983Sequence analysisAdd BLAST21
Coiled coili7178 – 7198Sequence analysisAdd BLAST21
Coiled coili7407 – 7427Sequence analysisAdd BLAST21
Coiled coili7570 – 7590Sequence analysisAdd BLAST21
Coiled coili7604 – 7635Sequence analysisAdd BLAST32

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi2927 – 2955PolyampholyteSequence analysisAdd BLAST29
Compositional biasi3070 – 3084PolarSequence analysisAdd BLAST15
Compositional biasi3085 – 3100PolyampholyteSequence analysisAdd BLAST16
Compositional biasi3101 – 3127PolarSequence analysisAdd BLAST27
Compositional biasi3157 – 3175PolarSequence analysisAdd BLAST19
Compositional biasi3248 – 3298PolyampholyteSequence analysisAdd BLAST51
Compositional biasi3299 – 3350PolarSequence analysisAdd BLAST52
Compositional biasi3351 – 3377PolyampholyteSequence analysisAdd BLAST27
Compositional biasi5627 – 5655PolarSequence analysisAdd BLAST29
Compositional biasi8285 – 8299PolyampholyteSequence analysisAdd BLAST15
Compositional biasi8546 – 8576PolarSequence analysisAdd BLAST31
Compositional biasi8594 – 8619PolarSequence analysisAdd BLAST26
Compositional biasi8627 – 8749PolarSequence analysisAdd BLAST123
Compositional biasi8760 – 8792PolarSequence analysisAdd BLAST33

Keywords - Domaini

Coiled coilSequence analysis, RepeatARBA annotation, SH3 domainPROSITE-ProRule annotationARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0516, Eukaryota
KOG1216, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00950000185013

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_000015_2_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		A1Z9J3

Database of Orthologous Groups

More...OrthoDBi		24858at2759

Family and domain databases

Conserved Domains Database

More...CDDi		cd00014, CH, 1 hit
cd00051, EFh, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.418.10, 1 hit
3.30.920.20, 1 hit
3.90.1290.10, 5 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR001715, CH-domain
IPR036872, CH_dom_sf
IPR041615, Desmoplakin_SH3
IPR011992, EF-hand-dom_pair
IPR018247, EF_Hand_1_Ca_BS
IPR002048, EF_hand_dom
IPR003108, GAR_dom
IPR036534, GAR_dom_sf
IPR043197, Plakin
IPR035915, Plakin_repeat_sf
IPR001101, Plectin_repeat
IPR001452, SH3_domain
IPR018159, Spectrin/alpha-actinin
IPR002017, Spectrin_repeat

The PANTHER Classification System

More...PANTHERi		PTHR23169, PTHR23169, 8 hits

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00307, CH, 1 hit
PF02187, GAS2, 1 hit
PF00681, Plectin, 1 hit
PF17902, SH3_10, 1 hit
PF00435, Spectrin, 16 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00033, CH, 1 hit
SM00054, EFh, 2 hits
SM00243, GAS2, 1 hit
SM00250, PLEC, 33 hits
SM00150, SPEC, 37 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF143575, SSF143575, 1 hit
SSF47473, SSF47473, 1 hit
SSF47576, SSF47576, 1 hit
SSF75399, SSF75399, 14 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50021, CH, 1 hit
PS00018, EF_HAND_1, 1 hit
PS50222, EF_HAND_2, 2 hits
PS51460, GAR, 1 hit
PS50002, SH3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 20 potential isoforms that are computationally mapped.Show allAlign All

A1Z9J3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MHSSSQSTLK RTQQLVRQTN GGRGDVLSSG SEVVHSSRGP AITTNIDDSN 
        60         70         80         90        100
LRYRHETKRE RTVEAVITDY PGVSPLGSVP HERTNFERTV TFQDPTGNSR 
       110        120        130        140        150
RLSETGALVP AGAIPTSSTH YQQVTRNKRI STEVLGSSVE STKTSQRAPN 
       160        170        180        190        200
GHRRVTTHIV RKVTTLSRAE ENAQPAEDLL PPAKMIRSSE LEYRRALPPA 
       210        220        230        240        250
IESSSTQRRE ISDIVVGKED NVSAREALLR WARRSTARYP GVRVNDFTSS 
       260        270        280        290        300
WRDGLAFSAL VHRNRPDLLD WRKARNDRPR ERLETAFHIV EKEYGVTRLL 
       310        320        330        340        350
DPEDVDTNEP DEKSLITYIS SLYDVFPEPP SIHPLFDMES QRRVHEYRDL 
       360        370        380        390        400
AQQFIYWCRE KTAYLQERSF PPTLIEMKRL LSDLQRFRSD EVSARKREKS 
       410        420        430        440        450
KLIQIYKELE RYFETVGEVD VEAELRPDAI EKAWYRMNTA LQDREVILQQ 
       460        470        480        490        500
EIERLERLQR LADKVQREIK HVDQKLTDLE GRIGEEGRRI ERLHPVDAKS 
       510        520        530        540        550
IVEALETEIR HLEEPIQDMN QDCHVLNEGR YPHVSELHKK VNKLHQRWAQ 
       560        570        580        590        600
LRTNFHTNLV QKLSGLKYPV HETTVTRQTR MVVESRQIDT NPHFRDLQEH 
       610        620        630        640        650
IEWCQNKLKQ LLAADYGSDL PSVKEELDRQ QHEHKIIDQF HTKILNDERQ 
       660        670        680        690        700
QTKFSGDELA LYQQRLNQLQ KVYAELLSTS TKRLSDLDSL QHFLGQASAE 
       710        720        730        740        750
LQWLNEKEQV EITRDWADKQ LDLPSVHRYY ENLMSELEKR EMHFATILDR 
       760        770        780        790        800
GEALLNQQHP ASKCIEAHLT ALQQQWAWLL QLTLCLEVHL KHATEYHQFF 
       810        820        830        840        850
GEIKDAEQWL AKRDEILNSK FSQSDFGLDQ GETLLRGMQD LREELNAFGE 
       860        870        880        890        900
TVATLQRRAQ TVVPLNKRRQ PVNRQGPVQA ICAYKQQGQL QIEKGETVTL 
       910        920        930        940        950
LDNSGRVKWR VRTAKGQEGP IPGACLLLPP PDQEAIDAAE RLKRLFDRSV 
       960        970        980        990       1000
ALWQKKHLRL RQNMIFATIR VVKGWDFDQF LAMGPEQRTA IRRALNDDAD 
      1010       1020       1030       1040       1050
KLLSEGDPND PQLRRLRREM DEVNRLFDEF EKRARAEEES KQASRIFTEE 
      1060       1070       1080       1090       1100
CLAIKSKLED MARELDQIIL APLPRDLDSL EHVLEIHSDY ERRLHLLEPE 
      1110       1120       1130       1140       1150
LKHLQETFRT IALKTPVLKK SLDNLMELWK ELNTQSGLHK DRLKLLEASL 
      1160       1170       1180       1190       1200
AGLEDNEHVI SELENELARH QDLPSTAEGL QQVFKQLNHM QDIITQQQPQ 
      1210       1220       1230       1240       1250
MDKMNDAADQ LGRMGVPTKV LGDLKRLHSN VERLNTRWSA VCNQLGERMR 
      1260       1270       1280       1290       1300
SCETAIGLMK NLQSSVQVEE SWVDGTTERL SAMPTATSAY ELDKLLGAAI 
      1310       1320       1330       1340       1350
ERKPKIENVN VAGGRLIREA KIYDSKCLRF VDWLVEARPS FSPPRRDLRP 
      1360       1370       1380       1390       1400
ADSDPGATQY YSQRLDNLNT KNDRLLEQLS QRLKTAIEVN GSDGLQYAES 
      1410       1420       1430       1440       1450
LQKPLKTFRV DFSAGSVPTG DGYAARQEDL YTTTYSTTQI SSTKTTKSST 
      1460       1470       1480       1490       1500
KSVYSSDGLD AASQEVSTAG LPQSQIQFNE IRTLKRSQQL GGHSVLDIAG 
      1510       1520       1530       1540       1550
IRDPRTGRVL TIGEAIQLRI LDVRTGEMLV GDRRITLEQA ADQGLIDLQL 
      1560       1570       1580       1590       1600
AKQLLEPGAG RDASGRELSL LEVIQREISE AESGYETAEK RIKVNNTVTV 
      1610       1620       1630       1640       1650
EQTSGELGSP ENPRNIADAI TAGSVDTKTG LYRVKSGQTI SLAEAYERGY 
      1660       1670       1680       1690       1700
LIRHESVTIK SNALCLSDAI AHGLVDGAGW IADRNSGDKF RLDSAIANQL 
      1710       1720       1730       1740       1750
IDASVREVVD AKRDTKITLQ EALQSGVLNA KTGRYVNEVT KEKLTFAEAR 
      1760       1770       1780       1790       1800
NRQLIVKPYT LKDICDLNLL DKQAQITSPM RREKLSIMQA IEAGVLDGNL 
      1810       1820       1830       1840       1850
LKCITKRKGE LVTLQEAIAD GIVLPAECKY RDFMTGELIS IPEAVERGLI 
      1860       1870       1880       1890       1900
SSVAQRSIFD IDGFKDLRSN DYVSFNVALS RDLLRRKSTG FALETGRDSL 
      1910       1920       1930       1940       1950
VPLEVAVSEG LVRQEVYEMF SRGIGVQNAS GKELSVFDLV YHNLIDPKTG 
      1960       1970       1980       1990       2000
YLLDPKTGET VPLDTAIERK FITPEGALLL SSLLNITLTT ETVTRTINRY 
      2010       2020       2030       2040       2050
VTIRAGSQEP VDSVLLTFTE AVRQGFIDEE RQLFKDPKTG NIYSVQQALN 
      2060       2070       2080       2090       2100
YGLLVPDSNQ TVPEPTNRKK TKSTITIVTK QIIPEAEPIK LNTQHTKYVE 
      2110       2120       2130       2140       2150
KSVEIPISQE LVKPHRVVSE FINLEKSSYI EQNVTERQIM ELPPGGWRLK 
      2160       2170       2180       2190       2200
DAIEQRLFNP DTGVFHVQGT DRLVNFEECI NKQIINNLSL SVIDPNTGDK 
      2210       2220       2230       2240       2250
ISVQSAFERD ILDSYGNYTN SRKQVQGMRS AIDESKIILE TVPATRGANQ 
      2260       2270       2280       2290       2300
KTILRITKVN NIPDVLEVST PLKDAPPKFV EVLTCQRELA SPEPLQIAPG 
      2310       2320       2330       2340       2350
AIYDPSTALV IFTQTGETEN IFDAARQGLV DEQLIKIVDP TTKQPISVTE 
      2360       2370       2380       2390       2400
AIARSIYDPK TATILDSEGQ PVDLITATKL GLLSVVGAPL VAAEGALRTV 
      2410       2420       2430       2440       2450
RFVTDPRTGE QIPVEVAYER GIVSRDQLHR GRSFDSEPAT VEDKVVVLQR 
      2460       2470       2480       2490       2500
MRKVILKPKD ALRKGIIDEE TCEILENTSN FTNPKGEVVN ITEALNTGLI 
      2510       2520       2530       2540       2550
DGRRGQVIDP QNNRVLNLRQ AVEQKIIDSE QTNHILMPLA KSLSVPRLAD 
      2560       2570       2580       2590       2600
QGLIDPQTQT IVHPESGYPL SIHEAIVCEV LDPHSKLHKP EKCTLEEAIT 
      2610       2620       2630       2640       2650
KGIINADDST FNYKNKTLNI TEAIEAKLFD PSYDQQKSKV EIPPVGMIFP 
      2660       2670       2680       2690       2700
VAVEKSLVEP SKRVVLHPST KKALPIKQAI EENFIMSIPY SPKPDAIEVV 
      2710       2720       2730       2740       2750
TAMEQDLIDV AAQTLTVPST GERIPLRQAM ENGVLVVKNL SDFVITQKPI 
      2760       2770       2780       2790       2800
PKTEIMETVR AVHTVTTKTI ELMQGYVLIS NNEVQNVNTG EVCSLEEAKE 
      2810       2820       2830       2840       2850
LGILREESTT RETKAAAGES PESVGDVGTS GDQTVIVEER TQTVVVSSDT 
      2860       2870       2880       2890       2900
RKQEMQVVST TQSTKDTSVP SVSEIETKGS KEPSKTLQNV KDAAKLGALG 
      2910       2920       2930       2940       2950
VIAAPVLAGG AIVSGVKSLI KSVKSPTEDA KSTEKPKEPQ TSFIEQERRK 
      2960       2970       2980       2990       3000
ELQPQQVPSE VDNLLSETEN FISSTTANFI ANEKQQDKPD TLPQESNLPL 
      3010       3020       3030       3040       3050
EVESTSTLTT TTVTTITTSS TTTETGNLEP VVVEDVSTTV KEDKVVVKPS 
      3060       3070       3080       3090       3100
TVPEDKTEVS KITETITTVT SNETDTVPEK ISQKSASEES AKKDPVVTKD 
      3110       3120       3130       3140       3150
TSSRPAETET SPKPVQKEPT PDPAQNTEFP ESIKKDPTPE PDYKETATEA 
      3160       3170       3180       3190       3200
AQITPKEASP APTNKNEQSA EPTSKPEPMP RTAKKEEISE IEPPFTAPLA 
      3210       3220       3230       3240       3250
PFVDQLAETK ITEIKTEFKE PVTSSQTITT ITTTVKTVDE HPIVEEVDEV 
      3260       3270       3280       3290       3300
SKSEKIVDVE EPTVHQQEPI KVNETSDDST RTEPTNEIVH EERVVTVEEP 
      3310       3320       3330       3340       3350
TITETTVTTT TITTTTTSSS EETLPQENTA TVKETPLNEP VPSSPAETKE 
      3360       3370       3380       3390       3400
IEQTTNDDQK KPEEIVDTEK KTTEQKPVET IPTEPISTSE TTTVTLTTKT 
      3410       3420       3430       3440       3450
TIVDEGKLHP PSDIEQIIQP HSTSDKHQSL VDFIEQEKGT QPAEGGSNIL 
      3460       3470       3480       3490       3500
QNVKDAAKLG ALAIVGAPVL AGKALVDALT TEKTLKPEHS TSQVVTETVE 
      3510       3520       3530       3540       3550
ELPTEIITTS TATLVTKVTT TTTTTTTSTS EGTPDDEALD VVKLPAELVE 
      3560       3570       3580       3590       3600
SSVKREVPRT LAIGDAISQK LISPDECQVI VDGEQQSQTV STLLKEEQLS 
      3610       3620       3630       3640       3650
PLDEVQIIDD KLIVLQQVSY LVDADTELTP QNLYELNIYD PENQYFIDPS 
      3660       3670       3680       3690       3700
TGQKISFHTL VFDMNVFNPE TILVKNFSTG KYETLTAALE RPLLDRHTGH 
      3710       3720       3730       3740       3750
MVDPKTGKKI PFFECVDRQW IIRANPEEQK PSGIENVTID TQTGQVVLDD 
      3760       3770       3780       3790       3800
GRVCSIVEAI NSGKLDIQSI SVRDPVSGEV IPLRMAIELG VVDMQAGTVI 
      3810       3820       3830       3840       3850
DIQTLKEIPM ELAFQLGFLV PGARKPISLE AAVRKGLYDP ETGKLFDSES 
      3860       3870       3880       3890       3900
QNQVDVQKSI EIGLVDPKIS LIVDTVTKKE VKLDCAIEDD LVLPATGQIK 
      3910       3920       3930       3940       3950
DNKNNTLVPF DVGVQQCLLK TDNVTWSLPE LLQREYYTPS TGKVLNPVTG 
      3960       3970       3980       3990       4000
EEILLQQAIE MGFVELETTL VKDVDHDKIL PGKEAAKVGL LDTVRGTLSS 
      4010       4020       4030       4040       4050
PNISLDEAFV KGYLISTKKP LSLVDCLLRG LYDPSTAKFT IDDKQLDLKA 
      4060       4070       4080       4090       4100
AIAQKLINPE ELVLLDPKTE SIISITEAIA KGYLDPIEGY VINPYASTKL 
      4110       4120       4130       4140       4150
SLHEALENRI LIPPKRKRSL PDAVYRGLYD PKTGQFSNTV TREKLTTERA 
      4160       4170       4180       4190       4200
IRRGILDPDS TVVNVGSGQI IPFGVATETG IVDSKHGTVR DADDHPIDFK 
      4210       4220       4230       4240       4250
EAFDRGILVE AKKPLRLIEA VVKNVYDEVD GHFVDPKSGE KLNFAEALNT 
      4260       4270       4280       4290       4300
NLLDEHSVQI RDFKTGLYKQ LNLTHAKDTG IIDAQNSKLL YNNQTMTLKH 
      4310       4320       4330       4340       4350
AFDIGILMDV NAPISIQRAI HQGLFDDKTG KLSDPRTGRQ ITLLESMRSF 
      4360       4370       4380       4390       4400
VVNPHLPCYF DEQTEQMYTL SETCRNGIIN RREGVFREPG SNSFVPLGEA 
      4410       4420       4430       4440       4450
LSLGLIVDIE NAGFGLYELL SMGFYETSTR KVLHPVTNRK LNLNEACVED 
      4460       4470       4480       4490       4500
VVSLSSSLVK HHETGKYLRL ANAIKEQLVD DSRGCYNLGN EQLDLQAARA 
      4510       4520       4530       4540       4550
RGLIVSNRRL LSLELVLRQQ LYRPETGKFC DPTTGEYLDL IEAIHSGFID 
      4560       4570       4580       4590       4600
PATTVFKNQL TGKELPLTEA IENGDIDVSK GRVFDPKSKS AYNYDVALSR 
      4610       4620       4630       4640       4650
GILVTITRPL TDRNDVVRRQ DSVELLNQTP VSVVISKPRE MSLEEAIRYN 
      4660       4670       4680       4690       4700
IIDPKTALVR DFDSFKFLPY SVAVERGLVD TTKRTLVDPK ALYFAFDPTL 
      4710       4720       4730       4740       4750
IVYVREPVTF DQAAESKCLD LQTGLLTYVP ASVPGSATAA PASDDSANDS 
      4760       4770       4780       4790       4800
LTVIETPKVY TLKEAASAGV VDPDSALVKD LAKAKLVRLP EAFRKGLMDA 
      4810       4820       4830       4840       4850
NKANVLNTQT SKLCTLQEAY ESGLICTPKR SFGLLEAITF NLYNPTNGCL 
      4860       4870       4880       4890       4900
VDPFQMHPDI IRRRKFTLAE AIGSGLVDPS STVVRDPSTG VIVPLTAAIS 
      4910       4920       4930       4940       4950
SGLIDATEGR LTDANEPKNN IDLVKAAEKG LLLPAEQRQA VFEKFNMCEE 
      4960       4970       4980       4990       5000
NVNDLLKWVT TVEQKISSVG GPREKIDELR NQINALKQIK DEIESQQRPV 
      5010       5020       5030       5040       5050
ATCLEQIRQI VLTGGDVLSA PEVTTLENSG RELRSRVDRV NDRTVRLLRR 
      5060       5070       5080       5090       5100
LEAGRDELTK LRSELDVFSD WLQVARRTLE DKERSLSDLT RLPSQADSVR 
      5110       5120       5130       5140       5150
EFVSDVIGHQ ADLRFITMAA QKFVDESKEF LAILNDFRTS LPERLPHVEP 
      5160       5170       5180       5190       5200
LSSAESPIRQ EVSLVSAQYK DLLNRVNALQ DRVSGLGGRQ REYQDALDKA 
      5210       5220       5230       5240       5250
NEWLRSVHPR VSRIISEPIA GDPKGVQDQM NEAKALHNEL LSSGRLVDNA 
      5260       5270       5280       5290       5300
QQALDNLLRS LGGQLSPMEI NQLELPIADL KNNYQQLLDN LGEHCKTLDK 
      5310       5320       5330       5340       5350
TLVQSQGVQD ALDSLVGWVN QAEDKFKMNL RPASLIKERL QEQIREHKVL 
      5360       5370       5380       5390       5400
LADLQSHQAS IDSVQVSAKH LLASASNARI AKKVESNLND VTVKFEKLYE 
      5410       5420       5430       5440       5450
KANKRGEFLD DVYNRLSRYL DEISTVEQRM ASLQEALDSR ETSLLSTEEL 
      5460       5470       5480       5490       5500
ARRMNELSRD KDQLAPQFED CVRSGKDLIS LRDVTDTGVL RDRIKALESQ 
      5510       5520       5530       5540       5550
WRNINISIDE RAKLSKQKAE QQLAYEGLKD QVLSWLASTE ARVNGLPPVA 
      5560       5570       5580       5590       5600
IDLDRIKQQH DELKPICKDY RDYAPTIDKI NDIGAQYDAL IRPESPARKR 
      5610       5620       5630       5640       5650
STYSPIKRTS PLRRMSGDAR SPSPTKGGIL SPLSTGSSGF GSRRSSQDGF 
      5660       5670       5680       5690       5700
QLSELSPVQQ QLSEINNRYG LIGVRLNDRQ HELDNLNEEL RKQYENLKGL 
      5710       5720       5730       5740       5750
AQFLERIQRQ LPKESVSNKD EAERCIKQAR KILEDMYEKQ SLLDTTKAQV 
      5760       5770       5780       5790       5800
KDILRRKSDV PGAEQLRQEN DSIQEKWKNL NDICKNRIAF SEKLRDFLDT 
      5810       5820       5830       5840       5850
HGNLKSWLDS KERMLTVLGP ISSDPRMVQS QVQQVQVLRE EFRTQQPQLK 
      5860       5870       5880       5890       5900
HFQELGHDVV DHLAGTPDAQ AVEIKLKDIL GKWDDLVGKL DDRANSLGGA 
      5910       5920       5930       5940       5950
ADSSKEFDAA VNRLREALQN ISDNLDTLPT DGDHQENLRK IENLERQLEG 
      5960       5970       5980       5990       6000
QRPLLADVEQ SAATLCNILG DPASRADVNS RVAALEKQYL ALQKKLDTKK 
      6010       6020       6030       6040       6050
AETEASLRDG RHFAENCSKT LGWLGGELSN LTDRLLVSAH KPTLQHQIDT 
      6060       6070       6080       6090       6100
HEPIYREVMA REHEVIMLIN KGKDLTDRQQ DRGVKRDLDR IQQQWEKLRR 
      6110       6120       6130       6140       6150
EAVDRHTRLQ TCMEHCKKYS QTSETFLAWL RTAEDKLADL TPGVLSKAKL 
      6160       6170       6180       6190       6200
ETRLRDLQTF RSEVWKHSGE FENTKGLGET FLSSCDIDKE PIKAELQDIR 
      6210       6220       6230       6240       6250
DRWERLNNDL IARAHEIENC SRRLDDFNDE LRNLDHSLGR CEDRLAAHDA 
      6260       6270       6280       6290       6300
LGGAAKDPKL LERVKAIREE LTNLSKPLQS LKALAKDISA EARAAGGDAD 
      6310       6320       6330       6340       6350
HLTSEVDGLA DRMSELQGRL DDRCGELQSA ATAVSQFNEQ MKSLGIDLND 
      6360       6370       6380       6390       6400
LETEIEKLSP PGREIKIVQV QIDDVGKIQT KLDRLVGRLE DAERAADVLV 
      6410       6420       6430       6440       6450
DAGFAADTTQ TREQISTLRK TLGRLDNRVR DHEDNLHSTL KALREFYDHQ 
      6460       6470       6480       6490       6500
SQTLDDIQDV SDEFKRMKPV GSELDQIRRQ QEDFRNFRER KVEPLAINVD 
      6510       6520       6530       6540       6550
KVNVAGRDLV RSAGSGVSTT AIEKDLEKLN DRWNDLKERM NERDRRLDVA 
      6560       6570       6580       6590       6600
LLQSGKFQEA LAGLSKWLSD TEEMVANQKP PSSDYKVVKA QLQEQKFLKK 
      6610       6620       6630       6640       6650
MLLDRQNSMG SLANLGKEVA NHCEPGERAS IEKQLNDLMK RFDALTDGAE 
      6660       6670       6680       6690       6700
QRELDLEEAM EVAKRFHDKI SPLELWLDNT ERSVKAMELI PTDEEKIQQR 
      6710       6720       6730       6740       6750
IREHDRLHDE ILGKKPDFSD LADVTAQLMH LVSDEEAVNL GEKVRGVTER 
      6760       6770       6780       6790       6800
YTGLVDASDN IGALLAESRQ GLRHLVLSYQ DLVAWMESME AELKRFKSVP 
      6810       6820       6830       6840       6850
VYAEKLLEQM DHLLELNENI AGHASNVEST VESGAELMKH ISNDEAIQLK 
      6860       6870       6880       6890       6900
DKLDSLQRRY GDLTNRGGDL LKSAQNALPL VQQFHEAHNR LVEWMQSAEA 
      6910       6920       6930       6940       6950
ALAPSEPRQA DVLRLEGELA DMRPILDSIN QVGPQLCQLS PGEGAATIES 
      6960       6970       6980       6990       7000
IVTRDNRRFD SIVEQIQRKA ERLHLSNQRA KEVTGDIDEL LEWFREMDTT 
      7010       7020       7030       7040       7050
LREADLPAME PKLVRAQLQE HRSINDDISS QKGRVRDVTA ASKKVLRESP 
      7060       7070       7080       7090       7100
QSENTATLRE KLDDLKEIVD TVAQLCSERL GILEQALPLS EHFADSHQGL 
      7110       7120       7130       7140       7150
TAWLDDMEQQ ISRLSMPALR PDQITLQQDK NERLLQSIAE HKPLLDKLNK 
      7160       7170       7180       7190       7200
TGEALGALVA DDDGAKINEI LDTDNARYAA LRLELRERQQ ALESALQESS 
      7210       7220       7230       7240       7250
QFSDKLEGML RALANTVDQV NQLDPLSALP QKIREQIEDN DALMDDLDKR 
      7260       7270       7280       7290       7300
QDAFSAVQRA ANDVIAKAGN KADPAVRDIK AKLEKLNNLW NDVQNATKKR 
      7310       7320       7330       7340       7350
GSSLDDILSV AEPFWKQLNS VMKTLKDLEE TLSCQEPPAA QPQDIKKQQV 
      7360       7370       7380       7390       7400
ALQEIRHEID QTKPEVEQVR RHGSNLMNMC GEPDKPEVKK HIEDLDNAWD 
      7410       7420       7430       7440       7450
NITALYAKRE ENLIDAMEKA MEFHETLQNL LKFLTKAEDK FAHLGAVGSD 
      7460       7470       7480       7490       7500
IDAVKRQIEQ LKSFKDEVDP HMVEVEALNR QAVELTERTS PEQAASIREP 
      7510       7520       7530       7540       7550
LSVVNRRWEA LLRGMVERQK QLEHALLHLG QFQHALNELL VWINKTDSTL 
      7560       7570       7580       7590       7600
DQLKPIPGDP QLLEVELAKL KVLANDIQAH QNSVDTLNDA GRQLIETEKG 
      7610       7620       7630       7640       7650
SVEASTTQEK LRKLNNEWKQ LLQKASDRQH ELEEALREAH GYIAEVQDIL 
      7660       7670       7680       7690       7700
GWLGDVDAVI GASKPVGGLP ETATEQLERF MEVYNELDEN RPKVETIQAQ 
      7710       7720       7730       7740       7750
GQEYIKRQNQ MKVSSSNLQH TLRTLKQRWD AVVSRASDKK IKLEIALKEA 
      7760       7770       7780       7790       7800
TEFHDTLQAF VEWLTQAEKL LSNAEPVSRV LETIQAQMEE HKVLQKDVST 
      7810       7820       7830       7840       7850
HREAMLLLDK KGTHLKYFSQ KQDVILIKNL LVSVQHRWER VVSKAAERTR 
      7860       7870       7880       7890       7900
ALDHGYKEAR EFNDAWSGMM QYLQETEQVL DQIIEEATAS KEPQKIKKYI 
      7910       7920       7930       7940       7950
GKLKETHRQL GAKQSVYDGT MRTGKNLLER APKGDRPVLD KMLIELKEQW 
      7960       7970       7980       7990       8000
TRVWSKSIDR QRKLEEALLL SGQFSDALGE LLDWLKKAKS RLNENGPVHG 
      8010       8020       8030       8040       8050
DLETVQGLCE HHKHIEQDLQ KRAAQMQGVL KTGRDLERSG NNPEVGRQLD 
      8060       8070       8080       8090       8100
EMQSIWEEVK SAVAKRGERL QVALVDAEKL NARVQALFDW LDHAEHKLRY 
      8110       8120       8130       8140       8150
AKNAPDDEKV SREMMDIHMD FMKDLRVRER EKTETFEYAE DIINKAYPDA 
      8160       8170       8180       8190       8200
IPIIKNWLSI IQQRWEEVRQ WAINRESKLE QHLQSLKDLD DTIEELLAWL 
      8210       8220       8230       8240       8250
SGLEGTLLNL KHEQLPDEIP PVEKLIEDHK EFMENTARRQ NEVDRACKPR 
      8260       8270       8280       8290       8300
QLPPGARKPS RSGKTPVFKG SRDQGLNARK GSRITPTRDT PDRDRLPHYG 
      8310       8320       8330       8340       8350
PRFSPSTSGP ELEFRSPRAK LLWTKWRDVW MLSWERQRLL NDHLLYLKDV 
      8360       8370       8380       8390       8400
ERARNFSWDD WRKRFLKYMN HKKSRLTDLF RKMDKDNNGM IPRDVFIDGI 
      8410       8420       8430       8440       8450
LNTKFDTSGL EMKAVADLFD RNGEGLIDWQ EFIAALRPDW QERKPANDSD 
      8460       8470       8480       8490       8500
KIHDEVKRLV MLCTCRQKFR VFQVGEGKYR FGDSQKLRLV RILRSTVMVR 
      8510       8520       8530       8540       8550
VGGGWVALDE FLQKNDPCRA KGRTNIELRE QFILADGVSQ SMAAFTPRRS 
      8560       8570       8580       8590       8600
TPNAAATASS SPHAHNGGSS NLPPYMSGQG PIIKVRERSV RSIPMSRPSR 
      8610       8620       8630       8640       8650
SSLSASTPDS LSDNEGSHGG PSGRYTPRKV TYTSTRTGLT PGGSRAGSKP 
      8660       8670       8680       8690       8700
NSRPLSRQGS KPPSRHGSTL SLDSTDDHTP SRIPQRKPST GSTASGTTPR 
      8710       8720       8730       8740       8750
PARLSVTTTT TPGSRLNGTS TITRKTASGS ASPAPTSNGG MSRSSSIPAL 
      8760       8770       8780       8790       8800
TGFGFKPIRR NISGSSTPSG MQTPRKSSAE PTFSSTMRRT SRGTTPTEKR 

EPFRL
Length:8,805
Mass (Da):989,549
Last modified:February 6, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i67E4BD3CC1DDE63F
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 20 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0B4K869A0A0B4K869_DROME
Short stop, isoform AD
shot 4, 42, CG18637, Dmel\CG18076, Grv
5,434Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A1Z9J0A1Z9J0_DROME
Short stop, isoform E
shot 4, 42, CG18637, Dmel\CG18076, Grv
5,201Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A1Z9I8A1Z9I8_DROME
Short stop, isoform G
shot 4, 42, CG18637, Dmel\CG18076, Grv
5,385Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A1Z9I9A1Z9I9_DROME
Short stop, isoform B
shot 4, 42, CG18637, Dmel\CG18076, Grv
5,390Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A1Z9J1A1Z9J1_DROME
Short stop, isoform A
shot 4, 42, CG18637, Dmel\CG18076, Grv
5,501Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A1Z9J2A1Z9J2_DROME
Short stop, isoform C
shot 4, 42, CG18637, Dmel\CG18076, Grv
5,160Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B7YZG3B7YZG3_DROME
Short stop, isoform I
shot 4, 42, CG18637, Dmel\CG18076, Grv
5,375Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B7YZG4B7YZG4_DROME
Short stop, isoform J
shot 4, 42, CG18637, Dmel\CG18076, Grv
5,368Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B7YZG2B7YZG2_DROME
Short stop, isoform K
shot 4, 42, CG18637, Dmel\CG18076, Grv
5,370Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B7YZG5B7YZG5_DROME
Short stop, isoform L
shot 4, 42, CG18637, Dmel\CG18076, Grv
5,486Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AE013599 Genomic DNA Translation: AAF58320.2

NCBI Reference Sequences

More...RefSeqi		NP_725339.1, NM_166019.3

Genome annotation databases

Ensembl metazoan genome annotation project

More...EnsemblMetazoai		FBtr0087621; FBpp0086747; FBgn0013733

Database of genes from NCBI RefSeq genomes

More...GeneIDi		36542

UCSC genome browser

More...UCSCi		CG18076-RH, d. melanogaster

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA Translation: AAF58320.2
RefSeqiNP_725339.1, NM_166019.3

3D structure databases

SMRiA1Z9J3
ModBaseiSearch...

Protein-protein interaction databases

IntActiA1Z9J3, 44 interactors
MINTiA1Z9J3
STRINGi7227.FBpp0086747

Proteomic databases

PaxDbiA1Z9J3
PRIDEiA1Z9J3

Genome annotation databases

EnsemblMetazoaiFBtr0087621; FBpp0086747; FBgn0013733
GeneIDi36542
UCSCiCG18076-RH, d. melanogaster

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		36542
FlyBaseiFBgn0013733, shot

Phylogenomic databases

eggNOGiKOG0516, Eukaryota
KOG1216, Eukaryota
GeneTreeiENSGT00950000185013
HOGENOMiCLU_000015_2_0_1
InParanoidiA1Z9J3
OrthoDBi24858at2759

Enzyme and pathway databases

ReactomeiR-DME-264870, Caspase-mediated cleavage of cytoskeletal proteins
R-DME-351906, Apoptotic cleavage of cell adhesion proteins
R-DME-446107, Type I hemidesmosome assembly
R-DME-6798695, Neutrophil degranulation
R-DME-6809371, Formation of the cornified envelope

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		36542, 0 hits in 3 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		shot, fly

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		36542

Gene expression databases

BgeeiFBgn0013733, Expressed in mouthpart (Drosophila) and 42 other tissues
ExpressionAtlasiA1Z9J3, baseline and differential
GenevisibleiA1Z9J3, DM

Family and domain databases

CDDicd00014, CH, 1 hit
cd00051, EFh, 1 hit
Gene3Di1.10.418.10, 1 hit
3.30.920.20, 1 hit
3.90.1290.10, 5 hits
InterProiView protein in InterPro
IPR001715, CH-domain
IPR036872, CH_dom_sf
IPR041615, Desmoplakin_SH3
IPR011992, EF-hand-dom_pair
IPR018247, EF_Hand_1_Ca_BS
IPR002048, EF_hand_dom
IPR003108, GAR_dom
IPR036534, GAR_dom_sf
IPR043197, Plakin
IPR035915, Plakin_repeat_sf
IPR001101, Plectin_repeat
IPR001452, SH3_domain
IPR018159, Spectrin/alpha-actinin
IPR002017, Spectrin_repeat
PANTHERiPTHR23169, PTHR23169, 8 hits
PfamiView protein in Pfam
PF00307, CH, 1 hit
PF02187, GAS2, 1 hit
PF00681, Plectin, 1 hit
PF17902, SH3_10, 1 hit
PF00435, Spectrin, 16 hits
SMARTiView protein in SMART
SM00033, CH, 1 hit
SM00054, EFh, 2 hits
SM00243, GAS2, 1 hit
SM00250, PLEC, 33 hits
SM00150, SPEC, 37 hits
SUPFAMiSSF143575, SSF143575, 1 hit
SSF47473, SSF47473, 1 hit
SSF47576, SSF47576, 1 hit
SSF75399, SSF75399, 14 hits
PROSITEiView protein in PROSITE
PS50021, CH, 1 hit
PS00018, EF_HAND_1, 1 hit
PS50222, EF_HAND_2, 2 hits
PS51460, GAR, 1 hit
PS50002, SH3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA1Z9J3_DROME
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A1Z9J3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: April 7, 2021
This is version 135 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again