Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

CG8545

Gene

CG8545-RA

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei467S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei494S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei511S-adenosyl-L-methioninePROSITE-ProRule annotation1
Active sitei568NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferasePROSITE-ProRule annotation, RNA-bindingPROSITE-ProRule annotation, Transferase
LigandS-adenosyl-L-methioninePROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
CG8545Imported
Submitted name:
LD11307pImported
Gene namesi
Name:CG8545-RAImported
ORF Names:CG8545Imported, Dmel_CG8545Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2R

Organism-specific databases

FlyBaseiFBgn0033741 CG8545

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PRIDEiA1Z909

Expressioni

Gene expression databases

BgeeiFBgn0033741

Interactioni

Protein-protein interaction databases

IntActiA1Z909, 2 interactors
STRINGi7227.FBpp0087045

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini351 – 638SAM_MT_RSMB_NOPInterPro annotationAdd BLAST288

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni443 – 449S-adenosyl-L-methionine bindingPROSITE-ProRule annotation7

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili240 – 260Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1122 Eukaryota
COG0144 LUCA
KOiK14835
OMAiDVQRCYN
OrthoDBiEOG091G0685

Family and domain databases

InterProiView protein in InterPro
IPR018314 Fmu/NOL1/Nop2p_CS
IPR031341 Methyltr_RsmF_N
IPR001678 MeTrfase_RsmB/NOP2
IPR011023 Nop2p
IPR023267 RCMT
IPR023273 RCMT_NOP2
IPR029063 SAM-dependent_MTases
PfamiView protein in Pfam
PF01189 Methyltr_RsmB-F, 1 hit
PF17125 Methyltr_RsmF_N, 1 hit
PRINTSiPR02008 RCMTFAMILY
PR02012 RCMTNOP2
SUPFAMiSSF53335 SSF53335, 1 hit
TIGRFAMsiTIGR00446 nop2p, 1 hit
PROSITEiView protein in PROSITE
PS01153 NOL1_NOP2_SUN, 1 hit
PS51686 SAM_MT_RSMB_NOP, 1 hit

Sequencei

Sequence statusi: Complete.

A1Z909-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRKAEYSEK PKKGPGRKAR KQGPPVFRKQ SFAPMEEEDK KLSHRQKQRF
60 70 80 90 100
VKREQKKVVQ KAKLQEKRAK GKLPQPAKRK TAYNSDSDPE DNEEEPQVAS
110 120 130 140 150
SDEEVPQLVP APKGQKATAP KGFTDDNDAW LKPKKQQKQP ETESEEEEEE
160 170 180 190 200
DEESEEDSED ELGEECEEEE EGDDEEGLES DDDTAQVGKL ADLSDDDDAN
210 220 230 240 250
SDDDFDISGE EDGAQADSDE EEDEDDDDDD DDDDDDKLPI ERANKKLKKR
260 270 280 290 300
EAEEAQLADD EMLETVDKQD VFQLPVEGEE TEKDLTLQEV QQRIKDVSLV
310 320 330 340 350
LSDFKRYRQA DRSRGEYIDL LRRDLCLYYS YNEFLMEKLM DMLPLTELME
360 370 380 390 400
YLEASEIARP LTIRTNTLKT RRRDLAGALI NRGVNLDPLG KWTKVGLVVF
410 420 430 440 450
NSQVPLGATP EYLAGHYMIQ GASSLLPVMA LAPQENERIL DMCSAPGGKG
460 470 480 490 500
SHIASIMKNT GVLFANDSNR DRIKAIVANF HRLGIVNAVV SCEDGTKFRN
510 520 530 540 550
IMTGFDRVLL DAPCTGTGVV SKDPSVKTTK SEVDVQRCYN LQRKLLLTAI
560 570 580 590 600
DCTDAKSSTG GYIVYSTCSV LPEENEWVID YALKKRNVKL VPTGLDFGVE
610 620 630 640 650
GFTKFRQHRF HPSLNLTKRY YPHTHNMDGF YVAKLKKFSN TIPITKEQQE
660 670 680 690 700
EDEKQLDEAI EADATTEAAA ESEEVEEEVA SKEKGPRKLL GKRAGKPSFT
710 720 730 740 750
EIEQELKKKK REESKTKYVA KVFEQPVKKP KPEKPAEKKN EKSQAPDKQT
760 770 780 790 800
NSSESPSKSA PKQKQTNGKT TVSNSDAKSF NKKNKGSQPK ENGAGSPAKP
810 820 830 840 850
DDNKPTTNGT NSPSKSAIKE TKTKPQPKGK QSPKGNAKLA KAPRVDIDDV
860 870 880 890
PILEGKPIKK QNKLKQKSKQ IGQLKKSTAG ANAGKKQKFK K
Length:891
Mass (Da):99,841
Last modified:February 6, 2007 - v1
Checksum:i679C9AB7B4E36CB1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA Translation: AAF58504.2
BT088930 mRNA Translation: ACT56594.1
RefSeqiNP_610786.2, NM_136942.3
UniGeneiDm.2211

Genome annotation databases

EnsemblMetazoaiFBtr0087934; FBpp0087045; FBgn0033741
GeneIDi36365
KEGGidme:Dmel_CG8545
UCSCiCG8545-RA d. melanogaster

Similar proteinsi

Entry informationi

Entry nameiA1Z909_DROME
AccessioniPrimary (citable) accession number: A1Z909
Entry historyiIntegrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: July 18, 2018
This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health