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Protein
Submitted name:

No child left behind

Gene

nclb

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • chromatin DNA binding Source: FlyBase

GO - Biological processi

  • cellular response to insulin stimulus Source: FlyBase
  • germ cell development Source: FlyBase
  • male germ-line stem cell population maintenance Source: FlyBase
  • male gonad development Source: FlyBase
  • ovarian follicle cell development Source: FlyBase
  • ovarian fusome organization Source: FlyBase
  • positive regulation of ribosome biogenesis Source: FlyBase
  • positive regulation of transcription by RNA polymerase III Source: FlyBase
  • positive regulation of transcription of nucleolar large rRNA by RNA polymerase I Source: FlyBase
  • regulation of gene expression Source: FlyBase

Enzyme and pathway databases

SignaLinkiA1Z8D0

Names & Taxonomyi

Protein namesi
Submitted name:
No child left behindImported
Gene namesi
Name:nclbImported
ORF Names:CG6751Imported, Dmel_CG6751Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2R

Organism-specific databases

FlyBaseiFBgn0263510 nclb

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiA1Z8D0
PRIDEiA1Z8D0

Expressioni

Gene expression databases

BgeeiFBgn0263510
ExpressionAtlasiA1Z8D0 baseline and differential
GenevisibleiA1Z8D0 DM

Interactioni

Protein-protein interaction databases

IntActiA1Z8D0, 1 interactor
STRINGi7227.FBpp0087323

Structurei

3D structure databases

ProteinModelPortaliA1Z8D0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini230 – 405WD_REPEATS_REGIONInterPro annotationAdd BLAST176
Repeati230 – 272WDPROSITE-ProRule annotationAdd BLAST43
Repeati363 – 405WDPROSITE-ProRule annotationAdd BLAST43

Keywords - Domaini

WD repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0270 Eukaryota
ENOG410XT1V LUCA
InParanoidiA1Z8D0
KOiK14791
OMAiPLCVEWL
OrthoDBiEOG091G07TA
PhylomeDBiA1Z8D0

Family and domain databases

InterProiView protein in InterPro
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PfamiView protein in Pfam
PF00400 WD40, 2 hits
SMARTiView protein in SMART
SM00320 WD40, 5 hits
SUPFAMiSSF50978 SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS00678 WD_REPEATS_1, 1 hit
PS50082 WD_REPEATS_2, 2 hits
PS50294 WD_REPEATS_REGION, 1 hit

Sequencei

Sequence statusi: Complete.

A1Z8D0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEEGPPEPS IDFVPALCFV PRGVAKDRPD KIVLTQAELA RIIGDTQQEL
60 70 80 90 100
DEESDDDAEE GENAEEDQND MDVDDHADAN SENRDPQDEF QFQEYDNEAN
110 120 130 140 150
ANVTSLANIV DAGEQIPDED EDSEAEDEVI KPSDNLILVG HVQDDAASME
160 170 180 190 200
VWVFNQEEEA LYTHHDFLLP SFPLCIEWMN HDAGSEKAGN MCAIGCMDPI
210 220 230 240 250
ITVWDLDIQD AIEPTFKLGS KGSRKQNKEQ YGHKDAVLDL SWNTNFEHIL
260 270 280 290 300
ASGSVDQTVI LWDMDEGQPH TTITAFGKQI QSLEFHPQEA QSILTGCADG
310 320 330 340 350
YVRLFDCRDA EGVNSSSIEW KVDGEVEKVL WHPTQTDYFI VGTNDGTLHY
360 370 380 390 400
ADKRSPGQLL WSVKAHNEEI SGVCFNNQKP NLLTSTSTEG TLKVWNFDGT
410 420 430 440 450
EAKHVYEHEF NMGRLQCMRQ CPEDPYTLAF GGEKPPRCAI FNIKNSIAVR

RTFGIPDAE
Length:459
Mass (Da):51,391
Last modified:February 6, 2007 - v1
Checksum:i2FBA9D1149599D75
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE013599 Genomic DNA Translation: AAF58738.1
RefSeqiNP_610623.1, NM_136779.4

Genome annotation databases

EnsemblMetazoaiFBtr0088228; FBpp0087323; FBgn0263510
GeneIDi36150
KEGGidme:Dmel_CG6751
UCSCiCG6751-RA d. melanogaster

Similar proteinsi

Entry informationi

Entry nameiA1Z8D0_DROME
AccessioniPrimary (citable) accession number: A1Z8D0
Entry historyiIntegrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: July 18, 2018
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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