UniProtKB - A1Z7X3 (A1Z7X3_DROME)
Protein
G_PROTEIN_RECEP_F1_2 domain-containing protein
Gene
Dmel\CG30340
Organism
Drosophila melanogaster (Fruit fly)
Status
Functioni
GO - Molecular functioni
- neuropeptide receptor activity Source: FlyBase
GO - Biological processi
- G protein-coupled receptor signaling pathway Source: FlyBase
Names & Taxonomyi
Protein namesi | Recommended name: G_PROTEIN_RECEP_F1_2 domain-containing proteinInterPro annotation |
Gene namesi | Name:Dmel\CG30340Imported Synonyms:BACR48G21.1Imported, BG:BACR48G21.1Imported ORF Names:CG30340Imported, Dmel_CG30340Imported |
Organismi | Drosophila melanogaster (Fruit fly)Imported |
Taxonomic identifieri | 7227 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
|
Organism-specific databases
FlyBasei | FBgn0050340, CG30340 |
Subcellular locationi
Other locations
- integral component of membrane Source: FlyBase
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 31 – 56 | HelicalSequence analysisAdd BLAST | 26 | |
Transmembranei | 68 – 88 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 108 – 127 | HelicalSequence analysisAdd BLAST | 20 | |
Transmembranei | 148 – 167 | HelicalSequence analysisAdd BLAST | 20 | |
Transmembranei | 194 – 220 | HelicalSequence analysisAdd BLAST | 27 | |
Transmembranei | 241 – 263 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 283 – 305 | HelicalSequence analysisAdd BLAST | 23 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | FBgn0050340, Expressed in midgut and 17 other tissues |
ExpressionAtlasi | A1Z7X3, baseline and differential |
Genevisiblei | A1Z7X3, DM |
Interactioni
Protein-protein interaction databases
IntActi | A1Z7X3, 1 interactor |
STRINGi | 7227.FBpp0087618 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 48 – 303 | G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST | 256 |
Sequence similaritiesi
Belongs to the G-protein coupled receptor 1 family.ARBA annotation
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
eggNOGi | KOG3656, Eukaryota |
GeneTreei | ENSGT00940000168939 |
HOGENOMi | CLU_009579_17_1_1 |
InParanoidi | A1Z7X3 |
OMAi | IMLICYI |
OrthoDBi | 1308959at2759 |
PhylomeDBi | A1Z7X3 |
Family and domain databases
InterProi | View protein in InterPro IPR000276, GPCR_Rhodpsn IPR017452, GPCR_Rhodpsn_7TM |
Pfami | View protein in Pfam PF00001, 7tm_1, 1 hit |
PRINTSi | PR00237, GPCRRHODOPSN |
SMARTi | View protein in SMART SM01381, 7TM_GPCR_Srsx, 1 hit |
PROSITEi | View protein in PROSITE PS50262, G_PROTEIN_RECEP_F1_2, 1 hit |
i Sequence
Sequence statusi: Complete.
A1Z7X3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MASVSSSDDF DFGKWDFPAE RIWLHKPNGE ITWKICTFLP LIAFGLYGNF
60 70 80 90 100
SMVYVIATNR SLRSPTNLII ANMAVADLLT LAICPAMFMV NDFYQNYQLG
110 120 130 140 150
CVGCKLEGFL VVVFLITAVL NLSVVSYDRL TAIVLPMETR LTIRGVQIVV
160 170 180 190 200
VCTWVSGILL ASPLAFYRSY RVRVWKNFTE RYCKENTSVL PKYWYVLITI
210 220 230 240 250
LVWLPLGIML ICYIAIFYKL DRYEKRVLSR ENPLTVSYKR SVAKTLFIVV
260 270 280 290 300
VVFAALRLPF TILVVLREKY FGEDVSVSSG MQLFWYISQY LMFLNAAVNP
310 320 330 340 350
LIYGFNNENF RRAYYQISWV RRWRDATQMK KFSRSPDHCC YCAFMKNGKR
360 370 380 390
TSEAAQKAGN LEKDISKDMS SAQQSAKSTK IVENEFVSEI EADGFI
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE013599 Genomic DNA Translation: AAM71077.2 |
RefSeqi | NP_724812.2, NM_165686.3 |
Genome annotation databases
EnsemblMetazoai | FBtr0088535; FBpp0087618; FBgn0050340 |
GeneIDi | 246550 |
KEGGi | dme:Dmel_CG30340 |
UCSCi | CG30340-RA, d. melanogaster |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE013599 Genomic DNA Translation: AAM71077.2 |
RefSeqi | NP_724812.2, NM_165686.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | A1Z7X3, 1 interactor |
STRINGi | 7227.FBpp0087618 |
Protein family/group databases
GPCRDBi | Search... |
Proteomic databases
PaxDbi | A1Z7X3 |
Genome annotation databases
EnsemblMetazoai | FBtr0088535; FBpp0087618; FBgn0050340 |
GeneIDi | 246550 |
KEGGi | dme:Dmel_CG30340 |
UCSCi | CG30340-RA, d. melanogaster |
Organism-specific databases
FlyBasei | FBgn0050340, CG30340 |
Phylogenomic databases
eggNOGi | KOG3656, Eukaryota |
GeneTreei | ENSGT00940000168939 |
HOGENOMi | CLU_009579_17_1_1 |
InParanoidi | A1Z7X3 |
OMAi | IMLICYI |
OrthoDBi | 1308959at2759 |
PhylomeDBi | A1Z7X3 |
Miscellaneous databases
BioGRID-ORCSi | 246550, 0 hits in 1 CRISPR screen |
GenomeRNAii | 246550 |
Gene expression databases
Bgeei | FBgn0050340, Expressed in midgut and 17 other tissues |
ExpressionAtlasi | A1Z7X3, baseline and differential |
Genevisiblei | A1Z7X3, DM |
Family and domain databases
InterProi | View protein in InterPro IPR000276, GPCR_Rhodpsn IPR017452, GPCR_Rhodpsn_7TM |
Pfami | View protein in Pfam PF00001, 7tm_1, 1 hit |
PRINTSi | PR00237, GPCRRHODOPSN |
SMARTi | View protein in SMART SM01381, 7TM_GPCR_Srsx, 1 hit |
PROSITEi | View protein in PROSITE PS50262, G_PROTEIN_RECEP_F1_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A1Z7X3_DROME | |
Accessioni | A1Z7X3Primary (citable) accession number: A1Z7X3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 6, 2007 |
Last sequence update: | February 6, 2007 | |
Last modified: | February 10, 2021 | |
This is version 108 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |