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UniProtKB - A1Z6U3 (A1Z6U3_DROME)
Protein
Submitted name:
IP01824p
Gene
Tsp42Ek
Organism
Drosophila melanogaster (Fruit fly)
Status
Names & Taxonomyi
Protein namesi | Submitted name: IP01824pImportedSubmitted name: Tetraspanin 42Ek, isoform AImportedSubmitted name: Tetraspanin 42Ek, isoform BImported |
Gene namesi | ORF Names:CG12841Imported, Dmel_CG12841Imported |
Organismi | Drosophila melanogaster (Fruit fly)Imported |
Taxonomic identifieri | 7227 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
|
Organism-specific databases
FlyBasei | FBgn0033133, Tsp42Ek |
VEuPathDBi | VectorBase:FBgn0033133 |
Subcellular locationi
Other locations
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Plasma Membrane
- integral component of plasma membrane Source: GO_Central
Other locations
- integral component of membrane Source: FlyBase
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 12 – 33 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 39 – 65 | HelicalSequence analysisAdd BLAST | 27 | |
Transmembranei | 72 – 92 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 186 – 203 | HelicalSequence analysisAdd BLAST | 18 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | FBgn0033133, Expressed in arthropod fat body and 24 other tissues |
Interactioni
Protein-protein interaction databases
IntActi | A1Z6U3, 4 interactors |
STRINGi | 7227.FBpp0296958 |
Structurei
Family & Domainsi
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisPhylogenomic databases
eggNOGi | KOG3882, Eukaryota |
HOGENOMi | CLU_055524_6_4_1 |
OMAi | APTAYII |
OrthoDBi | 1406905at2759 |
Family and domain databases
Gene3Di | 1.10.1450.10, 1 hit |
InterProi | View protein in InterPro IPR018499, Tetraspanin/Peripherin IPR008952, Tetraspanin_EC2_sf |
PANTHERi | PTHR19282, PTHR19282, 1 hit |
Pfami | View protein in Pfam PF00335, Tetraspanin, 1 hit |
SUPFAMi | SSF48652, SSF48652, 1 hit |
i Sequence
Sequence statusi: Complete.
A1Z6U3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGCTSGCVKC FLNTLNTLNA LSGLSLIAIA TLALSKAPIA YILFLYGLGG
60 70 80 90 100
IIFVSAVLGC CGICMENVCM TATYGFLLLA QLIISLLGIF RFKFTEEYIE
110 120 130 140 150
KFAAEEVQMK WDEELVEPGA MDIYQTVYEC CGRDSPDDYV AIGRQTLPPS
160 170 180 190 200
CYPQEDPQMP HYLAGCVQKS SENFVVLFSY AHDTNWIALG ITILMMIAAF
210
YLVGRFRKQR VRYTY
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE013599 Genomic DNA Translation: AAF59304.1 BT088928 mRNA Translation: ACT56592.1 AE013599 Genomic DNA Translation: AFH07916.1 |
RefSeqi | NP_001246161.1, NM_001259232.1 NP_523637.1, NM_078913.4 |
Genome annotation databases
EnsemblMetazoai | FBtr0089031; FBpp0088102; FBgn0033133 FBtr0305678; FBpp0296958; FBgn0033133 |
GeneIDi | 35621 |
KEGGi | dme:Dmel_CG12841 |
UCSCi | CG12841-RA, d. melanogaster |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE013599 Genomic DNA Translation: AAF59304.1 BT088928 mRNA Translation: ACT56592.1 AE013599 Genomic DNA Translation: AFH07916.1 |
RefSeqi | NP_001246161.1, NM_001259232.1 NP_523637.1, NM_078913.4 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | A1Z6U3, 4 interactors |
STRINGi | 7227.FBpp0296958 |
Protocols and materials databases
DNASUi | 35621 |
Genome annotation databases
EnsemblMetazoai | FBtr0089031; FBpp0088102; FBgn0033133 FBtr0305678; FBpp0296958; FBgn0033133 |
GeneIDi | 35621 |
KEGGi | dme:Dmel_CG12841 |
UCSCi | CG12841-RA, d. melanogaster |
Organism-specific databases
CTDi | 35621 |
FlyBasei | FBgn0033133, Tsp42Ek |
VEuPathDBi | VectorBase:FBgn0033133 |
Phylogenomic databases
eggNOGi | KOG3882, Eukaryota |
HOGENOMi | CLU_055524_6_4_1 |
OMAi | APTAYII |
OrthoDBi | 1406905at2759 |
Miscellaneous databases
BioGRID-ORCSi | 35621, 0 hits in 1 CRISPR screen |
ChiTaRSi | Tsp42Ek, fly |
GenomeRNAii | 35621 |
Gene expression databases
Bgeei | FBgn0033133, Expressed in arthropod fat body and 24 other tissues |
Family and domain databases
Gene3Di | 1.10.1450.10, 1 hit |
InterProi | View protein in InterPro IPR018499, Tetraspanin/Peripherin IPR008952, Tetraspanin_EC2_sf |
PANTHERi | PTHR19282, PTHR19282, 1 hit |
Pfami | View protein in Pfam PF00335, Tetraspanin, 1 hit |
SUPFAMi | SSF48652, SSF48652, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | A1Z6U3_DROME | |
Accessioni | A1Z6U3Primary (citable) accession number: A1Z6U3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 6, 2007 |
Last sequence update: | February 6, 2007 | |
Last modified: | January 19, 2022 | |
This is version 134 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |