Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
The new UniProt website is here! Take me to UniProt BETA

UniProtKB - A1YPR0 (ZBT7C_HUMAN)

Entry version 123 (25 May 2022)
Sequence version 1 (06 Feb 2007)
Previous versions | rss
Add a publicationFeedback
Protein

Zinc finger and BTB domain-containing protein 7C

Gene

ZBTB7C

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be a tumor suppressor gene.

1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri364 – 386C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri392 – 414C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri420 – 442C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri448 – 478C2H2-type 4; degeneratePROSITE-ProRule annotationAdd BLAST31

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		A1YPR0

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		A1YPR0

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger and BTB domain-containing protein 7C
Alternative name(s):
Affected by papillomavirus DNA integration in ME180 cells protein 1
Short name:
APM-1
Zinc finger and BTB domain-containing protein 36
Zinc finger protein 857C
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZBTB7C
Synonyms:APM1, ZBTB36, ZNF857C
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 18

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:31700, ZBTB7C

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		616591, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_A1YPR0

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000184828

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Keywords - Diseasei

Tumor suppressor

Organism-specific databases

DisGeNET

More...DisGeNETi		201501

Open Targets

More...OpenTargetsi		ENSG00000184828

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134861865

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		A1YPR0, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		ZBTB7C

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003378691 – 619Zinc finger and BTB domain-containing protein 7CAdd BLAST619

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		A1YPR0

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		A1YPR0

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		A1YPR0

PeptideAtlas

More...PeptideAtlasi		A1YPR0

PRoteomics IDEntifications database

More...PRIDEi		A1YPR0

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		162

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		A1YPR0

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		A1YPR0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Detected in normal cervical keratinocytes, and in some cervical carcinoma cell lines.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000184828, Expressed in nasal cavity epithelium and 172 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		A1YPR0, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		A1YPR0, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000184828, Tissue enhanced (esophagus)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		128390, 29 interactors

Database of interacting proteins

More...DIPi		DIP-61583N

Protein interaction database and analysis system

More...IntActi		A1YPR0, 4 interactors

Molecular INTeraction database

More...MINTi		A1YPR0

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000468782

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		A1YPR0, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

AlphaFold Protein Structure Database

More...AlphaFoldDBi		A1YPR0

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		A1YPR0

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini34 – 101BTBPROSITE-ProRule annotationAdd BLAST68

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni129 – 218DisorderedSequence analysisAdd BLAST90

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi130 – 176Acidic residuesSequence analysisAdd BLAST47

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri364 – 386C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri392 – 414C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri420 – 442C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri448 – 478C2H2-type 4; degeneratePROSITE-ProRule annotationAdd BLAST31

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1721, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000159814

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_025627_2_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		A1YPR0

Identification of Orthologs from Complete Genome Data

More...OMAi		ENDYSAY

Database of Orthologous Groups

More...OrthoDBi		1318335at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		A1YPR0

TreeFam database of animal gene trees

More...TreeFami		TF331824

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.30.710.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR016024, ARM-type_fold
IPR000210, BTB/POZ_dom
IPR011333, SKP1/BTB/POZ_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00651, BTB, 1 hit
PF00096, zf-C2H2, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00225, BTB, 1 hit
SM00355, ZnF_C2H2, 4 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48371, SSF48371, 1 hit
SSF54695, SSF54695, 1 hit
SSF57667, SSF57667, 2 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50097, BTB, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 3 hits
PS50157, ZINC_FINGER_C2H2_2, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

A1YPR0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MANDIDELIG IPFPNHSSEV LCSLNEQRHD GLLCDVLLVV QEQEYRTHRS 
        60         70         80         90        100
VLAACSKYFK KLFTAGTLAS QPYVYEIDFV QPEALAAILE FAYTSTLTIT 
       110        120        130        140        150
AGNVKHILNA ARMLEIQCIV NVCLEIMEPG GDGGEEDDKE DDDDDEDDDD 
       160        170        180        190        200
EEDEEEEEEE EEDDDDDTED FADQENLPDP QDISCHQSPS KTDHLTEKAY 
       210        220        230        240        250
SDTPRDFPDS FQAGSPGHLG VIRDFSIESL LRENLYPKAN IPDRRPSLSP 
       260        270        280        290        300
FAPDFFPHLW PGDFGAFAQL PEQPMDSGPL DLVIKNRKIK EEEKEELPPP 
       310        320        330        340        350
PPPPFPNDFF KDMFPDLPGG PLGPIKAEND YGAYLNFLSA THLGGLFPPW 
       360        370        380        390        400
PLVEERKLKP KASQQCPICH KVIMGAGKLP RHMRTHTGEK PYMCTICEVR 
       410        420        430        440        450
FTRQDKLKIH MRKHTGERPY LCIHCNAKFV HNYDLKNHMR IHTGVRPYQC 
       460        470        480        490        500
EFCYKSFTRS DHLHRHIKRQ SCRMARPRRG RKPAAWRAAS LLFGPGGPAP 
       510        520        530        540        550
DKAAFVMPPA LGEVGGHLGG AAVCLPGPSP AKHFLAAPKG ALSLQELERQ 
       560        570        580        590        600
FEETQMKLFG RAQLEAERNA GGLLAFALAE NVAAARPYFP LPDPWAAGLA 
       610 
GLPGLAGLNH VASMSEANN
Length:619
Mass (Da):69,017
Last modified:February 6, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i73D82A34502B55BF
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1B0GXF8A0A1B0GXF8_HUMAN
Zinc finger and BTB domain-containi...
ZBTB7C
66Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B2RG63B2RG63_HUMAN
Zinc finger and BTB domain containi...
ZBTB7C
25Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B2RG53B2RG53_HUMAN
Zinc finger and BTB domain-containi...
ZBTB7C
18Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B2RG76B2RG76_HUMAN
Zinc finger and BTB domain containi...
ZBTB7C
15Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
Y14591 mRNA Translation: CAA74933.1
EF120357 mRNA Translation: ABL98073.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS32830.1

NCBI Reference Sequences

More...RefSeqi		NP_001034449.1, NM_001039360.2
NP_001305770.1, NM_001318841.1
XP_005258286.1, XM_005258229.4
XP_011524172.1, XM_011525870.2
XP_011524173.1, XM_011525871.2
XP_016881098.1, XM_017025609.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000535628.6; ENSP00000439781.1; ENSG00000184828.10
ENST00000586438.5; ENSP00000468254.1; ENSG00000184828.10
ENST00000588982.5; ENSP00000468782.1; ENSG00000184828.10
ENST00000590800.6; ENSP00000467877.1; ENSG00000184828.10

Database of genes from NCBI RefSeq genomes

More...GeneIDi		201501

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:201501

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000590800.6; ENSP00000467877.1; NM_001318841.2; NP_001305770.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y14591 mRNA Translation: CAA74933.1
EF120357 mRNA Translation: ABL98073.1
CCDSiCCDS32830.1
RefSeqiNP_001034449.1, NM_001039360.2
NP_001305770.1, NM_001318841.1
XP_005258286.1, XM_005258229.4
XP_011524172.1, XM_011525870.2
XP_011524173.1, XM_011525871.2
XP_016881098.1, XM_017025609.1

3D structure databases

AlphaFoldDBiA1YPR0
SMRiA1YPR0
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi128390, 29 interactors
DIPiDIP-61583N
IntActiA1YPR0, 4 interactors
MINTiA1YPR0
STRINGi9606.ENSP00000468782

PTM databases

iPTMnetiA1YPR0
PhosphoSitePlusiA1YPR0

Genetic variation databases

BioMutaiZBTB7C

Proteomic databases

jPOSTiA1YPR0
MassIVEiA1YPR0
PaxDbiA1YPR0
PeptideAtlasiA1YPR0
PRIDEiA1YPR0
ProteomicsDBi162

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		2877, 77 antibodies from 15 providers

The DNASU plasmid repository

More...DNASUi		201501

Genome annotation databases

EnsembliENST00000535628.6; ENSP00000439781.1; ENSG00000184828.10
ENST00000586438.5; ENSP00000468254.1; ENSG00000184828.10
ENST00000588982.5; ENSP00000468782.1; ENSG00000184828.10
ENST00000590800.6; ENSP00000467877.1; ENSG00000184828.10
GeneIDi201501
KEGGihsa:201501
MANE-SelectiENST00000590800.6; ENSP00000467877.1; NM_001318841.2; NP_001305770.1

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		201501
DisGeNETi201501

GeneCards: human genes, protein and diseases

More...GeneCardsi		ZBTB7C
HGNCiHGNC:31700, ZBTB7C
HPAiENSG00000184828, Tissue enhanced (esophagus)
MIMi616591, gene
neXtProtiNX_A1YPR0
OpenTargetsiENSG00000184828
PharmGKBiPA134861865
VEuPathDBiHostDB:ENSG00000184828

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG1721, Eukaryota
GeneTreeiENSGT00940000159814
HOGENOMiCLU_025627_2_0_1
InParanoidiA1YPR0
OMAiENDYSAY
OrthoDBi1318335at2759
PhylomeDBiA1YPR0
TreeFamiTF331824

Enzyme and pathway databases

PathwayCommonsiA1YPR0
SignaLinkiA1YPR0

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		201501, 11 hits in 1132 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		ZBTB7C, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		201501
PharosiA1YPR0, Tbio

Protein Ontology

More...PROi		PR:A1YPR0
RNActiA1YPR0, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000184828, Expressed in nasal cavity epithelium and 172 other tissues
ExpressionAtlasiA1YPR0, baseline and differential
GenevisibleiA1YPR0, HS

Family and domain databases

Gene3Di3.30.710.10, 1 hit
InterProiView protein in InterPro
IPR016024, ARM-type_fold
IPR000210, BTB/POZ_dom
IPR011333, SKP1/BTB/POZ_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF00651, BTB, 1 hit
PF00096, zf-C2H2, 2 hits
SMARTiView protein in SMART
SM00225, BTB, 1 hit
SM00355, ZnF_C2H2, 4 hits
SUPFAMiSSF48371, SSF48371, 1 hit
SSF54695, SSF54695, 1 hit
SSF57667, SSF57667, 2 hits
PROSITEiView protein in PROSITE
PS50097, BTB, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 3 hits
PS50157, ZINC_FINGER_C2H2_2, 4 hits

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZBT7C_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A1YPR0
Secondary accession number(s): O73453
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: February 6, 2007
Last modified: May 25, 2022
This is version 123 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 18
    Human chromosome 18: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again