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Entry version 86 (08 May 2019)
Sequence version 1 (06 Feb 2007)
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Protein

Neurexin-1a

Gene

nrxn1a

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Neuronal cell surface protein that may be involved in cell recognition and cell adhesion.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi309CalciumBy similarity1
Metal bindingi326Calcium; via carbonyl oxygenBy similarity1
Metal bindingi394Calcium; via carbonyl oxygenBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell adhesion
LigandCalcium, Metal-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Neurexin-1a
Alternative name(s):
Neurexin Ia-alpha
Neurexin-1a-alpha
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:nrxn1a
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7955 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000437 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Zebrafish Information Network genome database

More...
ZFINi
ZDB-GENE-070206-1 nrxn1a

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini28 – 1415ExtracellularSequence analysisAdd BLAST1388
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei1416 – 1436HelicalSequence analysisAdd BLAST21
Topological domaini1437 – 1491CytoplasmicSequence analysisAdd BLAST55

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 27Sequence analysisAdd BLAST27
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000041253728 – 1491Neurexin-1aAdd BLAST1464

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi202 ↔ 214By similarity
Disulfide bondi208 ↔ 223By similarity
Disulfide bondi225 ↔ 235By similarity
Disulfide bondi424 ↔ 460By similarity
Disulfide bondi632 ↔ 661By similarity
Disulfide bondi669 ↔ 680By similarity
Disulfide bondi674 ↔ 689By similarity
Disulfide bondi691 ↔ 701By similarity
Disulfide bondi1041 ↔ 1069By similarity
Disulfide bondi1076 ↔ 1087By similarity
Disulfide bondi1081 ↔ 1096By similarity
Disulfide bondi1098 ↔ 1108By similarity

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
A1XQX0

PRoteomics IDEntifications database

More...
PRIDEi
A1XQX0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

After the very early developmental stages, the expression levels decrease and remain relatively constant until around 24 h, with the onset of an increase of expression that continues till the larval stages.1 Publication

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A1XQX0 baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
7955.ENSDARP00000087526

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A1XQX0

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini28 – 208Laminin G-like 1PROSITE-ProRule annotationAdd BLAST181
Domaini198 – 236EGF-like 1PROSITE-ProRule annotationAdd BLAST39
Domaini263 – 460Laminin G-like 2PROSITE-ProRule annotationAdd BLAST198
Domaini467 – 661Laminin G-like 3PROSITE-ProRule annotationAdd BLAST195
Domaini665 – 702EGF-like 2PROSITE-ProRule annotationAdd BLAST38
Domaini707 – 880Laminin G-like 4PROSITE-ProRule annotationAdd BLAST174
Domaini894 – 1069Laminin G-like 5PROSITE-ProRule annotationAdd BLAST176
Domaini1072 – 1109EGF-like 3PROSITE-ProRule annotationAdd BLAST38
Domaini1113 – 1314Laminin G-like 6PROSITE-ProRule annotationAdd BLAST202

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the neurexin family.Curated

Keywords - Domaini

EGF-like domain, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3514 Eukaryota
ENOG410XNU6 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000230481

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
A1XQX0

KEGG Orthology (KO)

More...
KOi
K07377

Database of Orthologous Groups

More...
OrthoDBi
35129at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
A1XQX0

TreeFam database of animal gene trees

More...
TreeFami
TF321302

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR013320 ConA-like_dom_sf
IPR000742 EGF-like_dom
IPR001791 Laminin_G
IPR003585 Neurexin-like
IPR027789 Syndecan/Neurexin_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00008 EGF, 1 hit
PF02210 Laminin_G_2, 6 hits
PF01034 Syndecan, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00294 4.1m, 1 hit
SM00181 EGF, 3 hits
SM00282 LamG, 6 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49899 SSF49899, 6 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50026 EGF_3, 3 hits
PS50025 LAM_G_DOMAIN, 6 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative promoter usage and alternative splicing. AlignAdd to basket
Note: A number of isoforms, alpha-type and beta-type are produced by alternative promoter usage. Beta-type isoforms differ from alpha-type isoforms in their N-terminus.

This entry has 2 described isoforms and 7 potential isoforms that are computationally mapped.Show allAlign All

Isoform Alpha (identifier: A1XQX0-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSFSMRNGAH LIWIGLLVCC LVDMGASMEF TGAEGQWARF PMWNACCESE
60 70 80 90 100
MSFNMKTKSA HGLLVYFDDE GFCDFLELLI HNGRLSLRFS IFCAEPATVF
110 120 130 140 150
SDTAVNDSRW HAVTLRRNFK NTTLVVDEEI KWVEVKSKRR DMTVFSHLFL
160 170 180 190 200
GGIPPELRSV ALRLTSSAIK DEVPYKGWIT NLRVNGSEPV LIGSDGVNSD
210 220 230 240 250
ICEADHICLN GGVCSIVNDE PICDCSETGF QGKDCSEEEA YVGGLAHLMM
260 270 280 290 300
GDQGKRKERE EYMATFKGSE YFCYDLSPNP IQSSSDEITL SFKTLQRNGL
310 320 330 340 350
MLHTGKSADY VNLALKNGAV SLVINLGSGA FEALVEPVNG KFNDNAWHDV
360 370 380 390 400
KVTRNLRQHS GIGHAMVNKL HCSVTISVDG ILTTTGYTQE DYTMLGSDDF
410 420 430 440 450
FYVGGSPSTA DLPGSPVSNN FMGCLKEVVY KNNDVRLELS RLAKLGDPKM
460 470 480 490 500
KVSGVVAFKC ENVATLDPVT FETPESFITL DKWSAKKAGS ISFDFRTTEP
510 520 530 540 550
NGLLLFSHGK PKPQQQKDPK SPKTLKVDFF AIEMLDGHLY LLLDMGSGTT
560 570 580 590 600
KTRAVNKKVN DGEWYHVDFQ RDGRSGTISV NSIRTPYNAP GESEILDLDD
610 620 630 640 650
KLYLGGLPED RAGLIFPTEV WTALLNYGYV GCVRDLFMDG QSKDIRRIAE
660 670 680 690 700
AQRAVGVKPS CSKEPPKQCL SNPCLNSGTC REGWNRYVCD CSGTGYLGRS
710 720 730 740 750
CERDATILSY DGSKFMKIQL PVVMHTEAED VSLRFRSQRA YGVLMATTSQ
760 770 780 790 800
NSADTLRLEL DGGRVRLTVN LDCIRINCTT SKGPETIFSG QNLNDNEWHT
810 820 830 840 850
VRVVRRGKSL KLMVDDLQPS EGQITGDHTQ LEFHNVETGI VTEKRYMPAV
860 870 880 890 900
PSNFIGHLQG LSFNGMSYID LCKNGDIDYC ELNAMIGYRS IVADPVTFKS
910 920 930 940 950
RSSYVTLPTL QAYYSMHLFF QFKTTSPDGL ILYNRGDGND FIVVELVKGY
960 970 980 990 1000
LHYVSDLGNG AHLIKGNSNT PLNDNHWHNV MISRDTNNLH TVKIDTKITT
1010 1020 1030 1040 1050
QTTMGAKNLD LKGDLYVGGV AKDMYKDLPK LVHSKEGFQG CLASVDLNGR
1060 1070 1080 1090 1100
LPDLQSDALS TAGQVERGCE GPSTTCQEDS CSNQGVCLQQ WEGFSCDCSM
1110 1120 1130 1140 1150
TSYGGPLCND PGTTYIFGRD GGLIVYTWPP NDRPSTRADR LAVGFSTQQK
1160 1170 1180 1190 1200
DAVLVRVDSS SGLGDYLQLQ IERGNIKVVF NVGTDDINIE ETSKFVNDGK
1210 1220 1230 1240 1250
YHIVRFTRSG GNATLQVDDL PVIERYPSGN IDNERLAIAR QRIPYRLGRV
1260 1270 1280 1290 1300
VDDWLLDKGR QLTIFNSQTT IKIGGWEKGS RPFQGQLSGL YYNGLKVLNM
1310 1320 1330 1340 1350
AAEGDPNVRV EGSARLVGDM PSSSITPQSS VSAAGNRSET SPSITDITTT
1360 1370 1380 1390 1400
TASNRQGKQT TTPQDDLLVA SAECPSDDED IDPCDPSSGG LAHPPLPEAK
1410 1420 1430 1440 1450
GYPSPEVIRE SSSTTGMVVG IVAAAALCIL ILLYAMYKYR NRDEGSYHVD
1460 1470 1480 1490
ESRNYISNSA TQPNGAAVKE KPIGVPKNKK DKKNKDKEYY V
Length:1,491
Mass (Da):164,313
Last modified:February 6, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBC00B3E400CE8473
GO
Isoform Beta (identifier: A1XQX1-1) [UniParc]FASTAAdd to basket
The sequence of this isoform can be found in the external entry A1XQX1.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Length:449
Mass (Da):48,706
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B6EUL5B6EUL5_DANRE
Neurexin Ia beta
nrxn1a
419Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2R8QKE7A0A2R8QKE7_DANRE
Neurexin-1a-beta
nrxn1a
1,481Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E7F420E7F420_DANRE
Neurexin-1a-beta
nrxn1a
1,477Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A140TAU1A0A140TAU1_DANRE
Neurexin-1a-beta
nrxn1a
1,484Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2R8QIT7A0A2R8QIT7_DANRE
Neurexin-1a-beta
nrxn1a
1,468Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2R8RRB9A0A2R8RRB9_DANRE
Neurexin-1a-beta
nrxn1a
1,470Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2R8QMY4A0A2R8QMY4_DANRE
Neurexin-1a-beta
nrxn1a
1,188Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
DQ641424 mRNA Translation: ABG25161.1

NCBI Reference Sequences

More...
RefSeqi
NP_001073490.1, NM_001080021.2 [A1XQX0-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSDART00000111239; ENSDARP00000102322; ENSDARG00000061647 [A1XQX0-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
565531

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dre:565531

Keywords - Coding sequence diversityi

Alternative promoter usage, Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ641424 mRNA Translation: ABG25161.1
RefSeqiNP_001073490.1, NM_001080021.2 [A1XQX0-1]

3D structure databases

SMRiA1XQX0
ModBaseiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000087526

Proteomic databases

PaxDbiA1XQX0
PRIDEiA1XQX0

Genome annotation databases

EnsembliENSDART00000111239; ENSDARP00000102322; ENSDARG00000061647 [A1XQX0-1]
GeneIDi565531
KEGGidre:565531

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
565531
ZFINiZDB-GENE-070206-1 nrxn1a

Phylogenomic databases

eggNOGiKOG3514 Eukaryota
ENOG410XNU6 LUCA
HOGENOMiHOG000230481
InParanoidiA1XQX0
KOiK07377
OrthoDBi35129at2759
PhylomeDBiA1XQX0
TreeFamiTF321302

Gene expression databases

ExpressionAtlasiA1XQX0 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR013320 ConA-like_dom_sf
IPR000742 EGF-like_dom
IPR001791 Laminin_G
IPR003585 Neurexin-like
IPR027789 Syndecan/Neurexin_dom
PfamiView protein in Pfam
PF00008 EGF, 1 hit
PF02210 Laminin_G_2, 6 hits
PF01034 Syndecan, 1 hit
SMARTiView protein in SMART
SM00294 4.1m, 1 hit
SM00181 EGF, 3 hits
SM00282 LamG, 6 hits
SUPFAMiSSF49899 SSF49899, 6 hits
PROSITEiView protein in PROSITE
PS50026 EGF_3, 3 hits
PS50025 LAM_G_DOMAIN, 6 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNR1AA_DANRE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A1XQX0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 21, 2011
Last sequence update: February 6, 2007
Last modified: May 8, 2019
This is version 86 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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