UniProtKB - A1XQU5 (RL27_PIG)
Protein
60S ribosomal protein L27
Gene
RPL27
Organism
Sus scrofa (Pig)
Status
Functioni
Component of the large ribosomal subunit (PubMed:24930395). Required for proper rRNA processing and maturation of 28S and 5.8S rRNAs (By similarity).By similarity1 Publication
GO - Molecular functioni
- structural constituent of ribosome Source: GO_Central
GO - Biological processi
- rRNA processing Source: UniProtKB
- translation Source: InterPro
Keywordsi
Molecular function | Ribonucleoprotein, Ribosomal protein |
Names & Taxonomyi
Protein namesi | Recommended name: 60S ribosomal protein L27 |
Gene namesi | Name:RPL27 |
Organismi | Sus scrofa (Pig) |
Taxonomic identifieri | 9823 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Artiodactyla › Suina › Suidae › Sus |
Proteomesi |
|
Organism-specific databases
VGNCi | VGNC:99035, RPL27 |
Subcellular locationi
Endoplasmic reticulum
- Rough endoplasmic reticulum 1 Publication
Cytoplasm and Cytosol
Note: Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (PubMed:24930395).By similarity1 Publication
Cytosol
- cytosolic large ribosomal subunit Source: GO_Central
Endoplasmic reticulum
- cytoplasmic side of rough endoplasmic reticulum membrane Source: UniProtKB
Other locations
- large ribosomal subunit Source: UniProtKB
Keywords - Cellular componenti
Cytoplasm, Endoplasmic reticulumPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000296385 | 1 – 136 | 60S ribosomal protein L27Add BLAST | 136 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 27 | N6-acetyllysineBy similarity | 1 | |
Modified residuei | 93 | N6-acetyllysineBy similarity | 1 |
Keywords - PTMi
AcetylationProteomic databases
PaxDbi | A1XQU5 |
PeptideAtlasi | A1XQU5 |
PRIDEi | A1XQU5 |
Expressioni
Gene expression databases
ExpressionAtlasi | A1XQU5, baseline and differential |
Genevisiblei | A1XQU5, SS |
Interactioni
Subunit structurei
Component of the large ribosomal subunit (PubMed:24930395).
Interacts with RRP1B (By similarity).
Component of the large ribosomal subunit.
Interacts with RRP1B.
Interacts with DHX33 (By similarity).
By similarity1 PublicationProtein-protein interaction databases
STRINGi | 9823.ENSSSCP00000024028 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 5 – 40 | KOWAdd BLAST | 36 |
Sequence similaritiesi
Belongs to the eukaryotic ribosomal protein eL27 family.Curated
Phylogenomic databases
eggNOGi | KOG3418, Eukaryota |
GeneTreei | ENSGT00390000010721 |
HOGENOMi | CLU_067359_0_1_1 |
InParanoidi | A1XQU5 |
OMAi | KPHDEGT |
OrthoDBi | 1584965at2759 |
Family and domain databases
CDDi | cd06090, KOW_RPL27, 1 hit |
Gene3Di | 2.30.30.770, 1 hit |
InterProi | View protein in InterPro IPR005824, KOW IPR041991, KOW_RPL27 IPR038655, L27e_sf IPR001141, Ribosomal_L27e IPR018262, Ribosomal_L27e_CS IPR008991, Translation_prot_SH3-like_sf |
PANTHERi | PTHR10497, PTHR10497, 1 hit |
Pfami | View protein in Pfam PF00467, KOW, 1 hit PF01777, Ribosomal_L27e, 1 hit |
SMARTi | View protein in SMART SM00739, KOW, 1 hit |
SUPFAMi | SSF50104, SSF50104, 1 hit |
PROSITEi | View protein in PROSITE PS01107, RIBOSOMAL_L27E, 1 hit |
i Sequence
Sequence statusi: Complete.
A1XQU5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGKFMKPGKV VLVLAGRYSG RKAVIVKNID DGTSDRPYSH ALVAGIDRYP
60 70 80 90 100
RKVTAAMGKK KIAKRSKIKS FVKVYNYNHL MPTRYSVDIP LDKTVVNKDV
110 120 130
FRDPALKRKA RREAKVKFEE RYKTGKNKWF FQKLRF
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | DQ629167 mRNA Translation: ABK55651.1 |
RefSeqi | NP_001090948.1, NM_001097479.1 |
Genome annotation databases
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | DQ629167 mRNA Translation: ABK55651.1 |
RefSeqi | NP_001090948.1, NM_001097479.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
3J7O | electron microscopy | 3.50 | Z | 1-136 | [»] | |
3J7P | electron microscopy | 3.50 | Z | 1-136 | [»] | |
3J7Q | electron microscopy | 3.50 | Z | 1-136 | [»] | |
3J7R | electron microscopy | 3.90 | Z | 1-136 | [»] | |
SMRi | A1XQU5 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 9823.ENSSSCP00000024028 |
Proteomic databases
PaxDbi | A1XQU5 |
PeptideAtlasi | A1XQU5 |
PRIDEi | A1XQU5 |
Genome annotation databases
Organism-specific databases
CTDi | 6155 |
VGNCi | VGNC:99035, RPL27 |
Phylogenomic databases
eggNOGi | KOG3418, Eukaryota |
GeneTreei | ENSGT00390000010721 |
HOGENOMi | CLU_067359_0_1_1 |
InParanoidi | A1XQU5 |
OMAi | KPHDEGT |
OrthoDBi | 1584965at2759 |
Gene expression databases
ExpressionAtlasi | A1XQU5, baseline and differential |
Genevisiblei | A1XQU5, SS |
Family and domain databases
CDDi | cd06090, KOW_RPL27, 1 hit |
Gene3Di | 2.30.30.770, 1 hit |
InterProi | View protein in InterPro IPR005824, KOW IPR041991, KOW_RPL27 IPR038655, L27e_sf IPR001141, Ribosomal_L27e IPR018262, Ribosomal_L27e_CS IPR008991, Translation_prot_SH3-like_sf |
PANTHERi | PTHR10497, PTHR10497, 1 hit |
Pfami | View protein in Pfam PF00467, KOW, 1 hit PF01777, Ribosomal_L27e, 1 hit |
SMARTi | View protein in SMART SM00739, KOW, 1 hit |
SUPFAMi | SSF50104, SSF50104, 1 hit |
PROSITEi | View protein in PROSITE PS01107, RIBOSOMAL_L27E, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | RL27_PIG | |
Accessioni | A1XQU5Primary (citable) accession number: A1XQU5 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 24, 2007 |
Last sequence update: | February 6, 2007 | |
Last modified: | April 7, 2021 | |
This is version 79 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- Ribosomal proteins
Ribosomal proteins families and list of entries - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families