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Protein

GTPase Der

Gene

der

Organism
Verminephrobacter eiseniae (strain EF01-2)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

GTPase that plays an essential role in the late steps of ribosome biogenesis.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi9 – 16GTP 1UniRule annotation8
Nucleotide bindingi56 – 60GTP 1UniRule annotation5
Nucleotide bindingi119 – 122GTP 1UniRule annotation4
Nucleotide bindingi205 – 212GTP 2UniRule annotation8
Nucleotide bindingi252 – 256GTP 2UniRule annotation5
Nucleotide bindingi317 – 320GTP 2UniRule annotation4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processRibosome biogenesis
LigandGTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
GTPase DerUniRule annotation
Alternative name(s):
GTP-binding protein EngAUniRule annotation
Gene namesi
Name:derUniRule annotation
Synonyms:engA
Ordered Locus Names:Veis_0076
OrganismiVerminephrobacter eiseniae (strain EF01-2)
Taxonomic identifieri391735 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaeVerminephrobacter
Proteomesi
  • UP000000374 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000117791 – 468GTPase DerAdd BLAST468

Interactioni

Subunit structurei

Associates with the 50S ribosomal subunit.UniRule annotation

Protein-protein interaction databases

STRINGi391735.Veis_0076

Structurei

3D structure databases

ProteinModelPortaliA1WE12
SMRiA1WE12
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 169EngA-type G 1Add BLAST167
Domaini199 – 372EngA-type G 2Add BLAST174
Domaini373 – 457KH-likeUniRule annotationAdd BLAST85

Sequence similaritiesi

Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.UniRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiCOG1160 LUCA
HOGENOMiHOG000242862
KOiK03977
OMAiFCNLPQY
OrthoDBiPOG091H00QI

Family and domain databases

Gene3Di3.30.300.20, 1 hit
HAMAPiMF_00195 GTPase_Der, 1 hit
InterProiView protein in InterPro
IPR031166 G_ENGA
IPR016484 GTP-bd_EngA
IPR006073 GTP_binding_domain
IPR032859 KH_dom-like
IPR015946 KH_dom-like_a/b
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
PfamiView protein in Pfam
PF14714 KH_dom-like, 1 hit
PF01926 MMR_HSR1, 2 hits
PIRSFiPIRSF006485 GTP-binding_EngA, 1 hit
PRINTSiPR00326 GTP1OBG
SUPFAMiSSF52540 SSF52540, 3 hits
TIGRFAMsiTIGR03594 GTPase_EngA, 1 hit
TIGR00231 small_GTP, 2 hits
PROSITEiView protein in PROSITE
PS51712 G_ENGA, 2 hits

Sequencei

Sequence statusi: Complete.

A1WE12-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKPVMALVGR ANVGKSTLFN RLTRSRDALV ADFAGLTRDR HYGNGKQGRH
60 70 80 90 100
EYIVIDTGGF EPDVASGIYR EMARQTQQAI AEADVVVFVV DVRAGVTAQD
110 120 130 140 150
HDIAHYLRRA GKPCVLAANK AEGMQQDQGG KWAEFYELGL GTVHPVSAAH
160 170 180 190 200
GQGIRSLVEM ALEPLSPPDD GADAAARDLP DADGVDGVDG VDGADGRIIR
210 220 230 240 250
LAVAGRPNVG KSTLINTWLG EERLVAFDTP GTTRDAITVP FERNGQRFEL
260 270 280 290 300
VDTAGLRRKG KVFAAVEKFS VVKTLQAIES AHVVLLLLDA SQGVTEQDAH
310 320 330 340 350
IAGYILESGR AVVLAVNKWD ATDDYQRQLL ERSIETRLAF LKFASLHRIS
360 370 380 390 400
AKKRQGLGPL WTAIVQAHKA ATCKMSTPVL TRLLLEAVQF QSPQRQGLFR
410 420 430 440 450
PKMRYAHQGG MNPPVIVIHG NGLEHVTDTY KRFLEGRFRK EFDLVGTPLR
460
IELKTSHNPY VDEGRGGR
Length:468
Mass (Da):51,207
Last modified:February 6, 2007 - v1
Checksum:i72569A81CD4BA1B9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000542 Genomic DNA Translation: ABM55869.1
RefSeqiWP_011807888.1, NC_008786.1

Genome annotation databases

EnsemblBacteriaiABM55869; ABM55869; Veis_0076
KEGGivei:Veis_0076

Similar proteinsi

Entry informationi

Entry nameiDER_VEREI
AccessioniPrimary (citable) accession number: A1WE12
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: February 28, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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