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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Mycobacterium sp. (strain KMS)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei172UniRule annotation1
Active sitei604UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotationImported
Biological processCarbon dioxide fixationUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Mkms_2454Imported
OrganismiMycobacterium sp. (strain KMS)Imported
Taxonomic identifieri189918 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacterium
Proteomesi
  • UP000000638 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliA1UFP3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotationSAAS annotation

Phylogenomic databases

HOGENOMiHOG000238647
KOiK01595
OMAiPWVFGWT
OrthoDBiPOG091H040O

Family and domain databases

HAMAPiMF_00595 PEPcase_type1, 1 hit
InterProiView protein in InterPro
IPR021135 PEP_COase
IPR022805 PEP_COase_bac/pln-type
IPR018129 PEP_COase_Lys_AS
IPR033129 PEPCASE_His_AS
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PANTHERiPTHR30523 PTHR30523, 1 hit
PfamiView protein in Pfam
PF00311 PEPcase, 1 hit
PRINTSiPR00150 PEPCARBXLASE
SUPFAMiSSF51621 SSF51621, 1 hit
PROSITEiView protein in PROSITE
PS00781 PEPCASE_1, 1 hit
PS00393 PEPCASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

A1UFP3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRRVRRTPIL ERMADLPEAL EPIGSVTRTE VGREASEPMR EDIRLLGAIL
60 70 80 90 100
GDTVREQNGE DVFDLVERAR VESFRVRRSE IDRAELAGLF DGIGVRAAIP
110 120 130 140 150
VIRAFTHFAL LANVAEDIHR ERRRAVHVAA GEPPQDSSLA ATYAKLDSAQ
160 170 180 190 200
LDSDEVSAAL SGALVSPVIT AHPTETRRRT VFDTQHRITE LMRLRAHGHE
210 220 230 240 250
TTDDGRDIEL ELRRHILTLW QTALIRLSRL KIQDEIETGL RYYRAAFFEV
260 270 280 290 300
IPRVNAEVRS ALQTRWPDAD LLAEPILRPG SWIGGDRDGN PNVTAEVVRQ
310 320 330 340 350
ATSRAAYTAF EHYFAELTGL EQELSMSARL VHVSDELAAL ADACHEAARA
360 370 380 390 400
DEPYRRALRV IHGRLTATAL EILDNQPEHE LDLGLERYAT PAELLADLDV
410 420 430 440 450
IDASLRGHGS AVLADDRLLR LREAVRVFGF HLSGLDMRQN SDVHEEVVAE
460 470 480 490 500
LLAWAGVHDD YASLPESDRI DLLVSELATR RPLTSQKAEL SELARKELDI
510 520 530 540 550
VRAGARAVRV FGPQAVPNYI ISMCESVSDM LEAAILLKEA GLLDVSDDEP
560 570 580 590 600
YAPVGIVPLF ETIDDLQRGS SILEAALDLP LYRGMVTARG DSQEVMLGYS
610 620 630 640 650
DSNKDGGYLA ANWALYRAEL DLVESSRKTG IRLRLFHGRG GTVGRGGGPS
660 670 680 690 700
YDAILAQPPG AVNGSLRITE QGEVIAAKYA EPRIAHRNLE TLVAATLEST
710 720 730 740 750
LLDVEGLGDE AGPAYEVLDD LAARAQRAYA ELVHETPGFV DYFKASTPVS
760 770 780 790 800
EIGALNIGSR PASRKPTTSI SDLRAIPWVL SWSQSRVMLP GWYGTGSAFE
810 820 830 840 850
QYIAEGAAES EDRLGVLQDL YRRWPFFRTV LSNMAQVLAK SDLGLAARYS
860 870 880 890 900
ELVEDEDLRR RVFDKIADEH ERTIRMHRLI TGQDDLLADN PALARSVFNR
910 920 930 940
FPYLEPLNHL QVELLRRYRS GEDDELVQRG ILLTMSGLAT ALRNSG
Length:946
Mass (Da):104,886
Last modified:February 6, 2007 - v1
Checksum:i73E65D55F5A78AA1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000518 Genomic DNA Translation: ABL91651.1

Genome annotation databases

EnsemblBacteriaiABL91651; ABL91651; Mkms_2454
KEGGimkm:Mkms_2454

Similar proteinsi

Entry informationi

Entry nameiA1UFP3_MYCSK
AccessioniPrimary (citable) accession number: A1UFP3
Entry historyiIntegrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: March 28, 2018
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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