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Protein

DNA replication and repair protein RecF

Gene

recF

Organism
Mycobacterium sp. (strain KMS)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi30 – 37ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processDNA damage, DNA repair, DNA replication, SOS response
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA replication and repair protein RecFUniRule annotation
Gene namesi
Name:recFUniRule annotation
Ordered Locus Names:Mkms_0012
OrganismiMycobacterium sp. (strain KMS)
Taxonomic identifieri189918 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacterium
Proteomesi
  • UP000000638 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000485441 – 380DNA replication and repair protein RecFAdd BLAST380

Structurei

3D structure databases

SMRiA1U8S3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RecF family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000269561
KOiK03629
OMAiGQQKSFL
OrthoDBiPOG091H00U7

Family and domain databases

HAMAPiMF_00365 RecF, 1 hit
InterProiView protein in InterPro
IPR001238 DNA-binding_RecF
IPR018078 DNA-binding_RecF_CS
IPR027417 P-loop_NTPase
IPR003395 RecF/RecN/SMC_N
PANTHERiPTHR32182:SF0 PTHR32182:SF0, 1 hit
PfamiView protein in Pfam
PF02463 SMC_N, 1 hit
SUPFAMiSSF52540 SSF52540, 2 hits
TIGRFAMsiTIGR00611 recf, 1 hit
PROSITEiView protein in PROSITE
PS00617 RECF_1, 1 hit
PS00618 RECF_2, 1 hit

Sequencei

Sequence statusi: Complete.

A1U8S3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFVRHLTLTD FRSWARADLE LEPGRTVFVG PNGFGKTNLV EALWYSATLG
60 70 80 90 100
SHRVASDAPL IRVGAPRAVV STIVVNEGRE LAVDLEITTG RANKARLNRS
110 120 130 140 150
PVRSPREVLG VLRAVLFAPE DLALVRGDPG ERRRYLDELA TTRRPSIAGV
160 170 180 190 200
RADYDRVIRQ RTALLKSAAG ARYRGDRSVL ETLDVWDGHL AAHGALLMAA
210 220 230 240 250
RADLVHHLAP EVEKAYQLLA PGSRPAAIRY RTSIDAEDDV SAEYYEAALL
260 270 280 290 300
DAMTRRRDAE LERGVCLVGP HRDDLELRLG DQMAKGYASH GESWSMALSL
310 320 330 340 350
RLAAYELLRT DGSDPVLLLD DVFAELDAAR RRALAEVAAS AEQVLVTAAV
360 370 380
AEDIPADWDA RRIMIRMQDD DDGRVSMVES
Length:380
Mass (Da):41,879
Last modified:February 6, 2007 - v1
Checksum:iF0EE31194BFFA861
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000518 Genomic DNA Translation: ABL89231.1
RefSeqiWP_011557432.1, NC_008705.1

Genome annotation databases

EnsemblBacteriaiABL89231; ABL89231; Mkms_0012
GeneIDi32418846
KEGGimkm:Mkms_0012

Similar proteinsi

Entry informationi

Entry nameiRECF_MYCSK
AccessioniPrimary (citable) accession number: A1U8S3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 6, 2007
Last modified: October 25, 2017
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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