We will be switching to the new UniProt website soon. Please explore and share your feedback.
Take me to the new website.
UniProtKB - A1U3K1 (UBIG_MARN8)
Protein
Ubiquinone biosynthesis O-methyltransferase
Gene
ubiG
Organism
Marinobacter nauticus (strain ATCC 700491 / DSM 11845 / VT8) (Marinobacter aquaeolei)
Status
Functioni
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
UniRule annotationCatalytic activityi
- a 3-demethylubiquinol + S-adenosyl-L-methionine = a ubiquinol + H+ + S-adenosyl-L-homocysteineUniRule annotationEC:2.1.1.64UniRule annotation
- a 3-(all-trans-polyprenyl)benzene-1,2-diol + S-adenosyl-L-methionine = a 2-methoxy-6-(all-trans-polyprenyl)phenol + H+ + S-adenosyl-L-homocysteineUniRule annotationEC:2.1.1.222UniRule annotation
: ubiquinone biosynthesis Pathwayi
This protein is involved in the pathway ubiquinone biosynthesis, which is part of Cofactor biosynthesis.UniRule annotationView all proteins of this organism that are known to be involved in the pathway ubiquinone biosynthesis and in Cofactor biosynthesis.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 38 | S-adenosyl-L-methionineUniRule annotation | 1 | |
Binding sitei | 57 | S-adenosyl-L-methionine; via carbonyl oxygenUniRule annotation | 1 | |
Binding sitei | 78 | S-adenosyl-L-methionineUniRule annotation | 1 | |
Binding sitei | 124 | S-adenosyl-L-methionine; via carbonyl oxygenUniRule annotation | 1 |
GO - Molecular functioni
- 2-polyprenyl-6-hydroxyphenol methylase activity Source: RHEA
- 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity Source: InterPro
- 3-demethylubiquinone-9 3-O-methyltransferase activity Source: UniProtKB-EC
GO - Biological processi
- methylation Source: UniProtKB-KW
- ubiquinone biosynthetic process Source: UniProtKB-UniRule
Keywordsi
Molecular function | Methyltransferase, Transferase |
Biological process | Ubiquinone biosynthesis |
Ligand | S-adenosyl-L-methionine |
Enzyme and pathway databases
UniPathwayi | UPA00232 |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:ubiGUniRule annotation Ordered Locus Names:Maqu_2495 |
Organismi | Marinobacter nauticus (strain ATCC 700491 / DSM 11845 / VT8) (Marinobacter aquaeolei) |
Taxonomic identifieri | 351348 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Marinobacteraceae › Marinobacter › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_1000206356 | 1 – 238 | Ubiquinone biosynthesis O-methyltransferaseAdd BLAST | 238 |
Family & Domainsi
Sequence similaritiesi
Phylogenomic databases
eggNOGi | COG2227, Bacteria |
HOGENOMi | CLU_042432_5_0_6 |
OMAi | RGTHDWE |
OrthoDBi | 1515497at2 |
Family and domain databases
HAMAPi | MF_00472, UbiG, 1 hit |
InterProi | View protein in InterPro IPR029063, SAM-dependent_MTases IPR010233, UbiG_MeTrfase |
SUPFAMi | SSF53335, SSF53335, 1 hit |
TIGRFAMsi | TIGR01983, UbiG, 1 hit |
i Sequence
Sequence statusi: Complete.
A1U3K1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MNNQNVDQNE IAKFEALASR WWDPTSEFKP LHDINPLRLN YIDERVSLAG
60 70 80 90 100
KRALDVGCGG GLLSEGMALR GAHVTGIDMG EAPLSVAKLH GLESGVKVDY
110 120 130 140 150
RQTTIEELAR DPEHAGQYDV VTCLEMLEHV PDPASVIRAC ASMLKPGGHM
160 170 180 190 200
FVSTINRNPK SFLFAIVGAE YVLNLLPKGT HEWKKFIRPS EMSDHLRHAG
210 220 230
LEVRELTGMT YNPITKVYKL GRDVDVNYLM HARDTRED
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP000514 Genomic DNA Translation: ABM19570.1 |
RefSeqi | WP_011785954.1, NC_008740.1 |
Genome annotation databases
EnsemblBacteriai | ABM19570; ABM19570; Maqu_2495 |
KEGGi | maq:Maqu_2495 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP000514 Genomic DNA Translation: ABM19570.1 |
RefSeqi | WP_011785954.1, NC_008740.1 |
3D structure databases
SMRi | A1U3K1 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 351348.Maqu_2495 |
Genome annotation databases
EnsemblBacteriai | ABM19570; ABM19570; Maqu_2495 |
KEGGi | maq:Maqu_2495 |
Phylogenomic databases
eggNOGi | COG2227, Bacteria |
HOGENOMi | CLU_042432_5_0_6 |
OMAi | RGTHDWE |
OrthoDBi | 1515497at2 |
Enzyme and pathway databases
UniPathwayi | UPA00232 |
Family and domain databases
HAMAPi | MF_00472, UbiG, 1 hit |
InterProi | View protein in InterPro IPR029063, SAM-dependent_MTases IPR010233, UbiG_MeTrfase |
SUPFAMi | SSF53335, SSF53335, 1 hit |
TIGRFAMsi | TIGR01983, UbiG, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | UBIG_MARN8 | |
Accessioni | A1U3K1Primary (citable) accession number: A1U3K1 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | September 22, 2009 |
Last sequence update: | February 6, 2007 | |
Last modified: | February 23, 2022 | |
This is version 93 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Documents
- PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families