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UniProtKB - A1L3B8 (A1L3B8_MOUSE)
Protein
Submitted name:
Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 7
Gene
Psmd7
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- isopeptidase activity Source: InterPro
- metal-dependent deubiquitinase activity Source: InterPro
- protein homodimerization activity Source: Ensembl
Protein family/group databases
MEROPSi | M67.973 |
Names & Taxonomyi
Protein namesi | Submitted name: Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 7Imported |
Gene namesi | Name:Psmd7Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Organism-specific databases
MGIi | MGI:1351511, Psmd7 |
VEuPathDBi | HostDB:ENSMUSG00000039067 |
Subcellular locationi
Nucleus
- nucleoplasm Source: Ensembl
Other locations
- proteasome regulatory particle Source: InterPro
Keywords - Cellular componenti
ProteasomeImportedARBA annotationPTM / Processingi
Proteomic databases
EPDi | A1L3B8 |
PeptideAtlasi | A1L3B8 |
PRIDEi | A1L3B8 |
PTM databases
SwissPalmi | A1L3B8 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000039067, Expressed in embryo and 306 other tissues |
ExpressionAtlasi | A1L3B8, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 9 – 144 | MPNInterPro annotationAdd BLAST | 136 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 281 – 321 | DisorderedSequence analysisAdd BLAST | 41 |
Sequence similaritiesi
Belongs to the peptidase M67A family.ARBA annotation
Phylogenomic databases
HOGENOMi | CLU_027018_3_0_1 |
OMAi | HAMSIKT |
OrthoDBi | 1275837at2759 |
PhylomeDBi | A1L3B8 |
Family and domain databases
CDDi | cd08062, MPN_RPN7_8, 1 hit |
InterProi | View protein in InterPro IPR000555, JAMM/MPN+_dom IPR037518, MPN IPR033858, MPN_RPN7_8 IPR024969, Rpn11/EIF3F_C |
Pfami | View protein in Pfam PF01398, JAB, 1 hit PF13012, MitMem_reg, 1 hit |
SMARTi | View protein in SMART SM00232, JAB_MPN, 1 hit |
PROSITEi | View protein in PROSITE PS50249, MPN, 1 hit |
i Sequence
Sequence statusi: Complete.
A1L3B8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPELAVQKVV VHPLVLLSVV DHFNRIGKVG NQKRVVGVLL GSWQKKVLDV
60 70 80 90 100
SNSFAVPFDE DDKDDSVWFL DHDYLENMYG MFKKVNARER IVGWYHTGPK
110 120 130 140 150
LHKNDIAINE LMKRYCPNSV LVIIDVKPKD LGLPTEAYIS VEEVHDDGTP
160 170 180 190 200
TSKTFEHVTS EIGAEEAEEV GVEHLLRDIK DTTVGTLSQR ITNQVHGLKG
210 220 230 240 250
LNSKLLDIRS YLEKVASGKL PINHQIIYQL QDVFNLLPDA SLQEFVKAFY
260 270 280 290 300
LKTNDQMVVV YLASLIRSVV ALHNLINNKI ANRDAEKKEG QEKEESKKER
310 320
KDDKEKEKSD AAKKEEKKEK K
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC130014 mRNA Translation: AAI30015.1 |
RefSeqi | NP_034947.1, NM_010817.2 |
Genome annotation databases
GeneIDi | 17463 |
KEGGi | mmu:17463 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC130014 mRNA Translation: AAI30015.1 |
RefSeqi | NP_034947.1, NM_010817.2 |
3D structure databases
SMRi | A1L3B8 |
ModBasei | Search... |
Protein family/group databases
MEROPSi | M67.973 |
PTM databases
SwissPalmi | A1L3B8 |
Proteomic databases
EPDi | A1L3B8 |
PeptideAtlasi | A1L3B8 |
PRIDEi | A1L3B8 |
Protocols and materials databases
Antibodypediai | 30221, 328 antibodies from 32 providers |
DNASUi | 17463 |
Genome annotation databases
GeneIDi | 17463 |
KEGGi | mmu:17463 |
Organism-specific databases
CTDi | 5713 |
MGIi | MGI:1351511, Psmd7 |
VEuPathDBi | HostDB:ENSMUSG00000039067 |
Phylogenomic databases
HOGENOMi | CLU_027018_3_0_1 |
OMAi | HAMSIKT |
OrthoDBi | 1275837at2759 |
PhylomeDBi | A1L3B8 |
Miscellaneous databases
BioGRID-ORCSi | 17463, 25 hits in 73 CRISPR screens |
ChiTaRSi | Psmd7, mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000039067, Expressed in embryo and 306 other tissues |
ExpressionAtlasi | A1L3B8, baseline and differential |
Family and domain databases
CDDi | cd08062, MPN_RPN7_8, 1 hit |
InterProi | View protein in InterPro IPR000555, JAMM/MPN+_dom IPR037518, MPN IPR033858, MPN_RPN7_8 IPR024969, Rpn11/EIF3F_C |
Pfami | View protein in Pfam PF01398, JAB, 1 hit PF13012, MitMem_reg, 1 hit |
SMARTi | View protein in SMART SM00232, JAB_MPN, 1 hit |
PROSITEi | View protein in PROSITE PS50249, MPN, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | A1L3B8_MOUSE | |
Accessioni | A1L3B8Primary (citable) accession number: A1L3B8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 6, 2007 |
Last sequence update: | February 6, 2007 | |
Last modified: | May 25, 2022 | |
This is version 115 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |