Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

TNR protein

Gene

TNR

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
TNR proteinImported
Gene namesi
Name:TNRImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA36642

PTM / Processingi

Proteomic databases

PeptideAtlasiA1L306
PRIDEiA1L306

Expressioni

Gene expression databases

GenevisibleiA1L306 HS

Interactioni

Binary interactionsi

Protein-protein interaction databases

IntActiA1L306, 7 interactors

Structurei

3D structure databases

ProteinModelPortaliA1L306
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini227 – 319Fibronectin type-IIIInterPro annotationAdd BLAST93
Domaini320 – 404Fibronectin type-IIIInterPro annotationAdd BLAST85
Domaini405 – 494Fibronectin type-IIIInterPro annotationAdd BLAST90
Domaini495 – 586Fibronectin type-IIIInterPro annotationAdd BLAST92
Domaini587 – 676Fibronectin type-IIIInterPro annotationAdd BLAST90
Domaini677 – 764Fibronectin type-IIIInterPro annotationAdd BLAST88
Domaini765 – 854Fibronectin type-IIIInterPro annotationAdd BLAST90
Domaini855 – 941Fibronectin type-IIIInterPro annotationAdd BLAST87
Domaini942 – 1029Fibronectin type-IIIInterPro annotationAdd BLAST88
Domaini1028 – 1243Fibrinogen C-terminalInterPro annotationAdd BLAST216

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili26 – 53Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1225 Eukaryota
KOG2579 Eukaryota
ENOG410ZYS4 LUCA
HOVERGENiHBG008949
KOiK06252

Family and domain databases

CDDicd00063 FN3, 9 hits
cd00087 FReD, 1 hit
Gene3Di2.60.40.10, 9 hits
InterProiView protein in InterPro
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR013111 EGF_extracell
IPR036056 Fibrinogen-like_C
IPR002181 Fibrinogen_a/b/g_C_dom
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR013783 Ig-like_fold
IPR033079 TNR
PANTHERiPTHR19143:SF254 PTHR19143:SF254, 4 hits
PfamiView protein in Pfam
PF07974 EGF_2, 1 hit
PF00147 Fibrinogen_C, 1 hit
PF00041 fn3, 9 hits
SMARTiView protein in SMART
SM00181 EGF, 4 hits
SM00186 FBG, 1 hit
SM00060 FN3, 9 hits
SUPFAMiSSF49265 SSF49265, 5 hits
SSF56496 SSF56496, 1 hit
PROSITEiView protein in PROSITE
PS00022 EGF_1, 1 hit
PS01186 EGF_2, 1 hit
PS51406 FIBRINOGEN_C_2, 1 hit
PS50853 FN3, 9 hits

Sequencei

Sequence statusi: Complete.

A1L306-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGQTSDHESQ VTFTHRINFP KKACPCASSA QVLQELLSRI EMLEREVSVL
60 70 80 90 100
RDQCNANCCQ ESAATGQLDY IPHCSGHGNF SFESCGCICN EGWFGKNCSE
110 120 130 140 150
PYCPLGCSSR GVCVDGQCIC DSEYSGDDCS ELRCPTDCSS RGLCVDGECV
160 170 180 190 200
CEEPYTGEDC RELRCPGDCS GKGRCANGTC LCEEGYVGED CGQRQCLNAC
210 220 230 240 250
SGRGQCEEGL CVCEEGYQGP DCSAVAPPED LRVAGISDRS IELEWDGPMA
260 270 280 290 300
VTEYVISYQP TALGGLQLQQ RVPGDWSGVT ITELEPGLTY NISVYAVISN
310 320 330 340 350
ILSLPITAKV ATHLSTPQGL QFKTITETTV EVQWEPFSFS FDGWEISFIP
360 370 380 390 400
KNNEGGVIAQ VPSDVTSFNQ TGLKPGEEYI VNVVALKEQA RSPPTSASVS
410 420 430 440 450
TVIDGPTQIL VRDVSDTVAF VEWIPPRAKV DFILLKYGLV GGEGGRTTFR
460 470 480 490 500
LQPPLSQYSV QALRPGSRYE VSVSAVRGTN ESDSATTQFT TEIDAPKNLR
510 520 530 540 550
VGSRTATSLD LEWDNSEAEV QEYKVVYSTL AGEQYHEVLV PRGIGPTTRA
560 570 580 590 600
TLTDLVPGTE YGVGISAVMN SQQSVPATMN ARTELDSPRD LMVTASSETS
610 620 630 640 650
ISLIWTKASG PIDHYRITFT PSSGIASEVT VPKDRTSYTL TDLEPGAEYI
660 670 680 690 700
ISVTAERGRQ QSLESTVDAF TGFRPISHLH FSHVTSSSVN ITWSDPSPPA
710 720 730 740 750
DRLILNYSPR DEEEEMMEVS LDATKRHAVL MGLQPATEYI VNLVAVHGTV
760 770 780 790 800
TSEPIVGSIT TGIDPPKDIT ISNVTKDSVM VSWSPPVASF DYYRVSYRPT
810 820 830 840 850
QVGRLDSSVV PNTVTEFTIT RLNPATEYEI SLNSVRGREE SERICTLVHT
860 870 880 890 900
AMDNPVDLIA TNITPTEALL QWKAPVGEVE NYVIVLTHFA VAGETILVDG
910 920 930 940 950
VSEEFRLVDL LPSTHYTATM YATNGPLTSG TISTNFSTLL DPPANLTASE
960 970 980 990 1000
VTRQSALISW QPPRAEIENY VLTYKSTDGS RKELIVDAED TWIRLEGLLE
1010 1020 1030 1040 1050
NTDYTVLLQA AQDTTWSSIT STAFTTGGRV FPHPQDCAQH LMNGDTLSGV
1060 1070 1080 1090 1100
YPIFLNGELS QKLQVYCDMT TDGGGWIVFQ RRQNGQTDFF RKWADYRVGF
1110 1120 1130 1140 1150
GNVEDEFWLG LDNIHRITSQ GRYELRVDMR DGQEAAFASY DRFSVEDSRN
1160 1170 1180 1190 1200
LYKLRIGSYN GTAGDSLSYH QGRPFSTEDR DNDVAVTNCA MSYKGAWWYK
1210 1220 1230 1240 1250
NCHRTNLNGK YGESRHSQGI NWYHWKGHEF SIPFVEMKMR PYNHRLMAGR

KRQSLQF
Length:1,257
Mass (Da):138,577
Last modified:February 6, 2007 - v1
Checksum:iC91D34380A00E43F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC129830 mRNA Translation: AAI29831.1
RefSeqiNP_003276.3, NM_003285.2
UniGeneiHs.659864

Genome annotation databases

GeneIDi7143
KEGGihsa:7143

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC129830 mRNA Translation: AAI29831.1
RefSeqiNP_003276.3, NM_003285.2
UniGeneiHs.659864

3D structure databases

ProteinModelPortaliA1L306
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiA1L306, 7 interactors

Proteomic databases

PeptideAtlasiA1L306
PRIDEiA1L306

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi7143
KEGGihsa:7143

Organism-specific databases

CTDi7143
PharmGKBiPA36642

Phylogenomic databases

eggNOGiKOG1225 Eukaryota
KOG2579 Eukaryota
ENOG410ZYS4 LUCA
HOVERGENiHBG008949
KOiK06252

Miscellaneous databases

ChiTaRSiTNR human
GenomeRNAii7143

Gene expression databases

GenevisibleiA1L306 HS

Family and domain databases

CDDicd00063 FN3, 9 hits
cd00087 FReD, 1 hit
Gene3Di2.60.40.10, 9 hits
InterProiView protein in InterPro
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR013111 EGF_extracell
IPR036056 Fibrinogen-like_C
IPR002181 Fibrinogen_a/b/g_C_dom
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR013783 Ig-like_fold
IPR033079 TNR
PANTHERiPTHR19143:SF254 PTHR19143:SF254, 4 hits
PfamiView protein in Pfam
PF07974 EGF_2, 1 hit
PF00147 Fibrinogen_C, 1 hit
PF00041 fn3, 9 hits
SMARTiView protein in SMART
SM00181 EGF, 4 hits
SM00186 FBG, 1 hit
SM00060 FN3, 9 hits
SUPFAMiSSF49265 SSF49265, 5 hits
SSF56496 SSF56496, 1 hit
PROSITEiView protein in PROSITE
PS00022 EGF_1, 1 hit
PS01186 EGF_2, 1 hit
PS51406 FIBRINOGEN_C_2, 1 hit
PS50853 FN3, 9 hits
ProtoNetiSearch...

Entry informationi

Entry nameiA1L306_HUMAN
AccessioniPrimary (citable) accession number: A1L306
Entry historyiIntegrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: July 18, 2018
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again