e2f3

Functionⁱ

GO - Molecular functionⁱ

DNA binding Source: UniProtKB-KW
DNA-binding transcription factor activity Source: InterPro

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

transcription, DNA-templated Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	DNA-bindingUniRule annotation
Biological process	Transcription, Transcription regulationUniRule annotation

Enzyme and pathway databases

Reactomeⁱ	R-DRE-68689 CDC6 association with the ORC:origin complex R-DRE-68911 G2 Phase R-DRE-69231 Cyclin D associated events in G1

Reactomeⁱ

R-DRE-68689 CDC6 association with the ORC:origin complex
R-DRE-68911 G2 Phase
R-DRE-69231 Cyclin D associated events in G1

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: E2F transcription factor 3Imported Submitted name: Zgc:158604Imported
Gene namesⁱ	Name:e2f3Imported ORF Names:zgc:158604Imported
Organismⁱ	Danio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifierⁱ	7955 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Actinopterygii › Actinopteri › Neopterygii › Teleostei › Osteoglossocephalai › Clupeocephala › Otomorpha › Ostariophysi › Otophysi › Cypriniphysae › Cypriniformes › Cyprinoidea › Cyprinidae › Danio
Proteomesⁱ	UP000000437 Componentⁱ: Chromosome 19

Organism-specific databases

ZFINⁱ	ZDB-GENE-070112-882 e2f3

ZFINⁱ

ZDB-GENE-070112-882 e2f3

Keywords - Cellular componentⁱ

NucleusUniRule annotation

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSDARG00000070463 Expressed in 28 organ(s), highest expression level in retina

Bgeeⁱ

ENSDARG00000070463 Expressed in 28 organ(s), highest expression level in retina

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	130 – 195	E2F_TDPInterPro annotationAdd BLAST		66

Sequence similaritiesⁱ

Belongs to the E2F/DP family.UniRule annotation

Phylogenomic databases

eggNOGⁱ	KOG2577 Eukaryota ENOG410XNYI LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00550000074403

Family and domain databases

Gene3Dⁱ	1.10.10.10, 1 hit
InterProⁱ	View protein in InterPro IPR015633 E2F IPR003316 E2F_WHTH_DNA-bd_dom IPR036388 WH-like_DNA-bd_sf IPR036390 WH_DNA-bd_sf
PANTHERⁱ	PTHR12081 PTHR12081, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF02319 E2F_TDP, 1 hit
SMARTⁱ	View protein in SMART SM01372 E2F_TDP, 1 hit
SUPFAMⁱ	SSF46785 SSF46785, 1 hit

Sequence (1+)ⁱ

Sequence statusⁱ: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show all Align All

A1L225-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MRKGGSSVPG QVMLTGVVRA EQHGVFTAVS DRRCAVYSNA TRIQINTPPS 
        60         70         80         90        100
TNNGCVPEAS ADSLYTTPLQ GSTHGTGLRP TLGRPPAKRR LELDITDHQY 
       110        120        130        140        150
SEPAKTLRSR KGALKLKIPK APKTPPEKTR YDTSLGFLTK KFCQLLAQSS 
       160        170        180        190        200
DGVLDLNKAA IVLNVQKRRL YDITNVLEGV RLIKKKSKNN IQWLWVTNRL 

AVHIRAA

Length:207

Mass (Da):22,824

Last modified:February 6, 2007 - v1

Checksum:ⁱ190F4D540B3DC54B

GO

Computationally mapped potential isoform sequencesⁱ

There is 1 potential isoform mapped to this entry.BLAST Align Show all Add to basket

	Entry	Entry name		Protein names	Gene names	Length	Annotation

	B8JLN4	B8JLN4_DANRE		E2F transcription factor 3 E2F transcription factor 3	e2f3	429	Annotation score:

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CU469458 Genomic DNA No translation available. BC129319 mRNA Translation: AAI29320.1
UniGeneⁱ	Dr.76098

Genome annotation databases

Ensemblⁱ	ENSDART00000103437; ENSDARP00000094213; ENSDARG00000070463

Ensemblⁱ

ENSDART00000103437; ENSDARP00000094213; ENSDARG00000070463

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CU469458 Genomic DNA No translation available. BC129319 mRNA Translation: AAI29320.1
UniGeneⁱ	Dr.76098

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSDART00000103437; ENSDARP00000094213; ENSDARG00000070463

Ensemblⁱ

ENSDART00000103437; ENSDARP00000094213; ENSDARG00000070463

Organism-specific databases

ZFINⁱ	ZDB-GENE-070112-882 e2f3

ZFINⁱ

ZDB-GENE-070112-882 e2f3

Phylogenomic databases

eggNOGⁱ	KOG2577 Eukaryota ENOG410XNYI LUCA
GeneTreeⁱ	ENSGT00550000074403

Enzyme and pathway databases

Reactomeⁱ	R-DRE-68689 CDC6 association with the ORC:origin complex R-DRE-68911 G2 Phase R-DRE-69231 Cyclin D associated events in G1

Reactomeⁱ

R-DRE-68689 CDC6 association with the ORC:origin complex
R-DRE-68911 G2 Phase
R-DRE-69231 Cyclin D associated events in G1

Gene expression databases

Bgeeⁱ	ENSDARG00000070463 Expressed in 28 organ(s), highest expression level in retina

Bgeeⁱ

ENSDARG00000070463 Expressed in 28 organ(s), highest expression level in retina

Family and domain databases

Gene3Dⁱ	1.10.10.10, 1 hit
InterProⁱ	View protein in InterPro IPR015633 E2F IPR003316 E2F_WHTH_DNA-bd_dom IPR036388 WH-like_DNA-bd_sf IPR036390 WH_DNA-bd_sf
PANTHERⁱ	PTHR12081 PTHR12081, 1 hit
Pfamⁱ	View protein in Pfam PF02319 E2F_TDP, 1 hit
SMARTⁱ	View protein in SMART SM01372 E2F_TDP, 1 hit
SUPFAMⁱ	SSF46785 SSF46785, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	A1L225_DANRE
Accessionⁱ	A1L225Primary (citable) accession number: A1L225
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	February 6, 2007
	Last sequence update:	February 6, 2007
	Last modified:	September 12, 2018
	This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - A1L225 (A1L225_DANRE)

Your basket is currently empty. i <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.<p><a href='/help/basket' target='_top'>More...</a></p>

E2F transcription factor 3

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Nucleus

Other locations

Keywords - Cellular componenti

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

UniProt is an ELIXIR core data resource

Your basket is currently empty. ⁱ

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Expressionⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ