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UniProtKB - A1L225 (A1L225_DANRE)
Protein
Submitted name:
E2F transcription factor 3
Gene
e2f3
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
GO - Molecular functioni
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO_Central
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
GO - Biological processi
- anatomical structure development Source: UniProt
- regulation of transcription by RNA polymerase II Source: GO_Central
Keywordsi
Molecular function | DNA-bindingUniRule annotationARBA annotation |
Biological process | Transcription, Transcription regulationUniRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: E2F transcription factor 3ImportedSubmitted name: Zgc:158604Imported |
Gene namesi | Name:e2f3Imported ORF Names:zgc:158604Imported |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio)Imported |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Proteomesi |
|
Organism-specific databases
ZFINi | ZDB-GENE-070112-882, e2f3 |
Subcellular locationi
Nucleus
- Nucleus UniRule annotation
Nucleus
- RNA polymerase II transcription regulator complex Source: GO_Central
Keywords - Cellular componenti
NucleusUniRule annotationExpressioni
Gene expression databases
Bgeei | ENSDARG00000070463, Expressed in retina and 32 other tissues |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 130 – 195 | E2F_TDPInterPro annotationAdd BLAST | 66 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 68 – 87 | DisorderedSequence analysisAdd BLAST | 20 |
Sequence similaritiesi
Phylogenomic databases
GeneTreei | ENSGT00940000155115 |
HOGENOMi | CLU_1325992_0_0_1 |
Family and domain databases
Gene3Di | 1.10.10.10, 1 hit |
InterProi | View protein in InterPro IPR015633, E2F IPR003316, E2F_WHTH_DNA-bd_dom IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
PANTHERi | PTHR12081, PTHR12081, 1 hit |
Pfami | View protein in Pfam PF02319, E2F_TDP, 1 hit |
SMARTi | View protein in SMART SM01372, E2F_TDP, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
A1L225-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MRKGGSSVPG QVMLTGVVRA EQHGVFTAVS DRRCAVYSNA TRIQINTPPS
60 70 80 90 100
TNNGCVPEAS ADSLYTTPLQ GSTHGTGLRP TLGRPPAKRR LELDITDHQY
110 120 130 140 150
SEPAKTLRSR KGALKLKIPK APKTPPEKTR YDTSLGFLTK KFCQLLAQSS
160 170 180 190 200
DGVLDLNKAA IVLNVQKRRL YDITNVLEGV RLIKKKSKNN IQWLWVTNRL
AVHIRAA
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketB8JLN4 | B8JLN4_DANRE | E2F transcription factor 3 | e2f3 | 429 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU469458 Genomic DNA No translation available. BC129319 mRNA Translation: AAI29320.1 |
Genome annotation databases
Ensembli | ENSDART00000103437; ENSDARP00000094213; ENSDARG00000070463 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU469458 Genomic DNA No translation available. BC129319 mRNA Translation: AAI29320.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
Ensembli | ENSDART00000103437; ENSDARP00000094213; ENSDARG00000070463 |
Organism-specific databases
ZFINi | ZDB-GENE-070112-882, e2f3 |
Phylogenomic databases
GeneTreei | ENSGT00940000155115 |
HOGENOMi | CLU_1325992_0_0_1 |
Gene expression databases
Bgeei | ENSDARG00000070463, Expressed in retina and 32 other tissues |
Family and domain databases
Gene3Di | 1.10.10.10, 1 hit |
InterProi | View protein in InterPro IPR015633, E2F IPR003316, E2F_WHTH_DNA-bd_dom IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
PANTHERi | PTHR12081, PTHR12081, 1 hit |
Pfami | View protein in Pfam PF02319, E2F_TDP, 1 hit |
SMARTi | View protein in SMART SM01372, E2F_TDP, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | A1L225_DANRE | |
Accessioni | A1L225Primary (citable) accession number: A1L225 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 6, 2007 |
Last sequence update: | February 6, 2007 | |
Last modified: | January 19, 2022 | |
This is version 106 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |