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Protein
Submitted name:

Ccnk protein

Gene

Ccnk

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionCyclinUniRule annotationSAAS annotation

Enzyme and pathway databases

ReactomeiR-RNO-112382 Formation of RNA Pol II elongation complex
R-RNO-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
R-RNO-674695 RNA Polymerase II Pre-transcription Events
R-RNO-6796648 TP53 Regulates Transcription of DNA Repair Genes
R-RNO-6807505 RNA polymerase II transcribes snRNA genes
R-RNO-75955 RNA Polymerase II Transcription Elongation

Names & Taxonomyi

Protein namesi
Submitted name:
Ccnk proteinImported
Submitted name:
Cyclin KImported
Gene namesi
Name:CcnkImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 6

Organism-specific databases

RGDi1595690 Ccnk

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSRNOG00000006985 Expressed in 10 organ(s), highest expression level in testis

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000053998

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini55 – 149CYCLINInterPro annotationAdd BLAST95
Domaini158 – 278Cyclin_CInterPro annotationAdd BLAST121
Domaini162 – 256CYCLINInterPro annotationAdd BLAST95

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili304 – 327Sequence analysisAdd BLAST24

Sequence similaritiesi

Belongs to the cyclin family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0834 Eukaryota
COG5333 LUCA
GeneTreeiENSGT00760000119191
HOGENOMiHOG000220828
HOVERGENiHBG050836
OMAiNSYMSGE
OrthoDBiEOG091G0H4W
TreeFamiTF101010

Family and domain databases

CDDicd00043 CYCLIN, 2 hits
InterProiView protein in InterPro
IPR013763 Cyclin-like
IPR036915 Cyclin-like_sf
IPR004367 Cyclin_C-dom
IPR006671 Cyclin_N
PfamiView protein in Pfam
PF02984 Cyclin_C, 1 hit
PF00134 Cyclin_N, 1 hit
SMARTiView protein in SMART
SM00385 CYCLIN, 2 hits
SM01332 Cyclin_C, 1 hit
SUPFAMiSSF47954 SSF47954, 2 hits

Sequencei

Sequence statusi: Complete.

A1L1L5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKENKENSSP SVTSANLDHT KPCWYWDKKD LAHTPSQLEG LDPATEARYR
60 70 80 90 100
REGARFIFDV GTRLGLHYDT LATGIIYFHR FYMFHSFKQF PRYVTGACCL
110 120 130 140 150
FLAGKVEETP KKCKDIIKTA RSLLNDVQFG QFGDDPKEEV MVLERILLQT
160 170 180 190 200
IKFDLQVEHP YQFLLKYAKQ LKGDKNKIQK LVQMAWTFVN DSLCTTLSLQ
210 220 230 240 250
WEPEIIAVAV MYLAGRLCKF EIQEWTSKPM YRRWWEQFVQ DVPVDVLEDI
260 270 280 290 300
CHQILDLYSQ GKQQMPHHTP HQLQQPPSLQ PTPQVPPVPQ AQPSQGSEAA
310 320 330 340 350
QPQQKDAQQQ QQQQQQQQQQ QQQQAQQPKK PSPQPSPPRQ AKRAVVVSPK
360 370 380 390 400
EENKATEPPP PPKIPKLEAA HPPLPPAHPP PDRKLPLAPA LGEAEPTGPV
410 420 430 440 450
ETSDLPKVQI PPPAHPAPVH QPPPLPHRPP PPPPSSYMTG MSTTSSYMSG
460 470 480 490 500
EGYQSLQSMM KTEGPSYGAL PPAYGPPAHL TYHPHVYPPN PPPPPVPPPP
510 520 530 540 550
ASFPPPTIPP PTPGYPPPPP TYNPNFPPPP PRLPPTHAVP PHPPPGLGLP
560 570 580
PASYPPPAVP PGGQPPVPPP IPPPGMPPVG GLGRAAWMR
Length:589
Mass (Da):65,367
Last modified:February 6, 2007 - v1
Checksum:iBA58E0A497A55F7F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07065498 Genomic DNA No translation available.
BC129121 mRNA Translation: AAI29122.1
RefSeqiNP_001103142.1, NM_001109672.1
XP_006240611.1, XM_006240549.3
XP_006240613.1, XM_006240551.3
UniGeneiRn.23

Genome annotation databases

EnsembliENSRNOT00000057171; ENSRNOP00000053998; ENSRNOG00000006985
ENSRNOT00000083208; ENSRNOP00000074580; ENSRNOG00000006985
GeneIDi500715
KEGGirno:500715

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07065498 Genomic DNA No translation available.
BC129121 mRNA Translation: AAI29122.1
RefSeqiNP_001103142.1, NM_001109672.1
XP_006240611.1, XM_006240549.3
XP_006240613.1, XM_006240551.3
UniGeneiRn.23

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000053998

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000057171; ENSRNOP00000053998; ENSRNOG00000006985
ENSRNOT00000083208; ENSRNOP00000074580; ENSRNOG00000006985
GeneIDi500715
KEGGirno:500715

Organism-specific databases

CTDi8812
RGDi1595690 Ccnk

Phylogenomic databases

eggNOGiKOG0834 Eukaryota
COG5333 LUCA
GeneTreeiENSGT00760000119191
HOGENOMiHOG000220828
HOVERGENiHBG050836
OMAiNSYMSGE
OrthoDBiEOG091G0H4W
TreeFamiTF101010

Enzyme and pathway databases

ReactomeiR-RNO-112382 Formation of RNA Pol II elongation complex
R-RNO-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
R-RNO-674695 RNA Polymerase II Pre-transcription Events
R-RNO-6796648 TP53 Regulates Transcription of DNA Repair Genes
R-RNO-6807505 RNA polymerase II transcribes snRNA genes
R-RNO-75955 RNA Polymerase II Transcription Elongation

Gene expression databases

BgeeiENSRNOG00000006985 Expressed in 10 organ(s), highest expression level in testis

Family and domain databases

CDDicd00043 CYCLIN, 2 hits
InterProiView protein in InterPro
IPR013763 Cyclin-like
IPR036915 Cyclin-like_sf
IPR004367 Cyclin_C-dom
IPR006671 Cyclin_N
PfamiView protein in Pfam
PF02984 Cyclin_C, 1 hit
PF00134 Cyclin_N, 1 hit
SMARTiView protein in SMART
SM00385 CYCLIN, 2 hits
SM01332 Cyclin_C, 1 hit
SUPFAMiSSF47954 SSF47954, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiA1L1L5_RAT
AccessioniPrimary (citable) accession number: A1L1L5
Entry historyiIntegrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: October 10, 2018
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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