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Protein

Scavenger receptor cysteine-rich domain-containing group B protein

Gene

Ssc4d

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Recommended name:
Scavenger receptor cysteine-rich domain-containing group B proteinBy similarity
Alternative name(s):
Four scavenger receptor cysteine-rich domains-containing proteinBy similarity
S4D-SRCRBBy similarity
Gene namesi
Name:Ssc4dImported
Synonyms:Srcrb4dImported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 5

Organism-specific databases

MGIiMGI:1924709 Ssc4d

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 58Sequence analysisAdd BLAST58
ChainiPRO_000032258259 – 586Scavenger receptor cysteine-rich domain-containing group B proteinSequence analysisAdd BLAST528

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi94 ↔ 158PROSITE-ProRule annotation
Disulfide bondi107 ↔ 168PROSITE-ProRule annotation
Disulfide bondi138 ↔ 148PROSITE-ProRule annotation
Disulfide bondi225 ↔ 289PROSITE-ProRule annotation
Disulfide bondi238 ↔ 299PROSITE-ProRule annotation
Disulfide bondi269 ↔ 279PROSITE-ProRule annotation
Disulfide bondi380 ↔ 444PROSITE-ProRule annotation
Disulfide bondi393 ↔ 454PROSITE-ProRule annotation
Disulfide bondi424 ↔ 434PROSITE-ProRule annotation
Disulfide bondi509 ↔ 573PROSITE-ProRule annotation
Disulfide bondi522 ↔ 583PROSITE-ProRule annotation
Disulfide bondi553 ↔ 563PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiA1L0T3
PeptideAtlasiA1L0T3
PRIDEiA1L0T3

Expressioni

Gene expression databases

BgeeiENSMUSG00000029699 Expressed in 129 organ(s), highest expression level in vestibular epithelium
ExpressionAtlasiA1L0T3 baseline and differential
GenevisibleiA1L0T3 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000106782

Structurei

3D structure databases

ProteinModelPortaliA1L0T3
SMRiA1L0T3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini69 – 169SRCR 1PROSITE-ProRule annotationAdd BLAST101
Domaini200 – 300SRCR 2PROSITE-ProRule annotationAdd BLAST101
Domaini355 – 455SRCR 3PROSITE-ProRule annotationAdd BLAST101
Domaini484 – 584SRCR 4PROSITE-ProRule annotationAdd BLAST101

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiENOG410IHBC Eukaryota
ENOG410XQVR LUCA
GeneTreeiENSGT00900000140803
HOGENOMiHOG000290652
HOVERGENiHBG031373
InParanoidiA1L0T3
OMAiDWAWHTD
OrthoDBiEOG091G0DF7
PhylomeDBiA1L0T3
TreeFamiTF329295

Family and domain databases

Gene3Di3.10.250.10, 4 hits
InterProiView protein in InterPro
IPR001190 SRCR
IPR017448 SRCR-like_dom
IPR036772 SRCR-like_dom_sf
PfamiView protein in Pfam
PF00530 SRCR, 4 hits
PRINTSiPR00258 SPERACTRCPTR
SMARTiView protein in SMART
SM00202 SR, 4 hits
SUPFAMiSSF56487 SSF56487, 4 hits
PROSITEiView protein in PROSITE
PS00420 SRCR_1, 4 hits
PS50287 SRCR_2, 4 hits

Sequence (1+)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

A1L0T3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGPSERPSIG WTPKEAEMQI GPQPDGWSRG WKPGDRGAVP LPLSPALSFL
60 70 80 90 100
LLFPLASALQ PTPLPFPELR LVGGPSRCRG RLEVMHSGSW GSVCDDDWDV
110 120 130 140 150
VDANVVCRQL GCGLALPVPR PLAFGQGRGP IFLDNVECRG QEASLSECGS
160 170 180 190 200
RGWGVHNCFH YEDVAVLCDE FLHTQPPTRK VLTSMAPATA LQNGKGEGSV
210 220 230 240 250
RLVGGASPCQ GRVEILHGGV WGTVCDDDWG LQDAAVVCRQ LGCGVALAAT
260 270 280 290 300
TNAFFGYGTG HILLDNVHCE GGEPRLAACQ SLGWGVHNCG HHEDAGVLCA
310 320 330 340 350
VLSPPTSTAL PPSVTKEDWA RHTGPAATGV GASPSRDTVW LTTAARASGK
360 370 380 390 400
KSGRLRLVGG PSPCRGRVEV LYAGGWGTVC DDDWDFADAR VACREAGCGP
410 420 430 440 450
ALGATGLGHF GYGRGPVLLD NVGCTGTEAR LSDCFHLGWG QHNCGHHEDA
460 470 480 490 500
GALCAGPEEL GLQVQQAGSE TTRMPSPRPR DGHLRLASGT HRCEGRVELF
510 520 530 540 550
LGQRWGTVCD DAWDLRAAIV LCRQLGCGQA LAAPGEAHFG PGRGPILLDN
560 570 580
VKCRGDESTL LLCSHIRWDV HNCDHSEDAS VLCQPL
Length:586
Mass (Da):61,916
Last modified:February 26, 2008 - v2
Checksum:i3C7230F0AE43768A
GO

Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F6ZA92F6ZA92_MOUSE
Scavenger receptor cysteine-rich do...
Ssc4d Srcrb4d
116Annotation score:
D3YUQ6D3YUQ6_MOUSE
Scavenger receptor cysteine-rich do...
Ssc4d Srcrb4d
174Annotation score:
F7AS28F7AS28_MOUSE
Scavenger receptor cysteine-rich do...
Ssc4d Srcrb4d
166Annotation score:
D3YZ07D3YZ07_MOUSE
MCG1887, isoform CRA_b
Ssc4d Srcrb4d, mCG_1887
108Annotation score:
G3X988G3X988_MOUSE
MCG1887, isoform CRA_d
Ssc4d Srcrb4d, mCG_1887
134Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC087420 Genomic DNA No translation available.
BC117747 mRNA Translation: AAI17748.1
BC126947 mRNA Translation: AAI26948.1
CCDSiCCDS51664.1
RefSeqiNP_001153838.1, NM_001160366.1
XP_006504400.1, XM_006504337.1
UniGeneiMm.332750

Genome annotation databases

EnsembliENSMUST00000111152; ENSMUSP00000106782; ENSMUSG00000029699
ENSMUST00000111153; ENSMUSP00000106783; ENSMUSG00000029699
GeneIDi109267
KEGGimmu:109267
UCSCiuc008zzj.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC087420 Genomic DNA No translation available.
BC117747 mRNA Translation: AAI17748.1
BC126947 mRNA Translation: AAI26948.1
CCDSiCCDS51664.1
RefSeqiNP_001153838.1, NM_001160366.1
XP_006504400.1, XM_006504337.1
UniGeneiMm.332750

3D structure databases

ProteinModelPortaliA1L0T3
SMRiA1L0T3
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000106782

Proteomic databases

PaxDbiA1L0T3
PeptideAtlasiA1L0T3
PRIDEiA1L0T3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000111152; ENSMUSP00000106782; ENSMUSG00000029699
ENSMUST00000111153; ENSMUSP00000106783; ENSMUSG00000029699
GeneIDi109267
KEGGimmu:109267
UCSCiuc008zzj.2 mouse

Organism-specific databases

CTDi136853
MGIiMGI:1924709 Ssc4d

Phylogenomic databases

eggNOGiENOG410IHBC Eukaryota
ENOG410XQVR LUCA
GeneTreeiENSGT00900000140803
HOGENOMiHOG000290652
HOVERGENiHBG031373
InParanoidiA1L0T3
OMAiDWAWHTD
OrthoDBiEOG091G0DF7
PhylomeDBiA1L0T3
TreeFamiTF329295

Miscellaneous databases

PROiPR:A1L0T3
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000029699 Expressed in 129 organ(s), highest expression level in vestibular epithelium
ExpressionAtlasiA1L0T3 baseline and differential
GenevisibleiA1L0T3 MM

Family and domain databases

Gene3Di3.10.250.10, 4 hits
InterProiView protein in InterPro
IPR001190 SRCR
IPR017448 SRCR-like_dom
IPR036772 SRCR-like_dom_sf
PfamiView protein in Pfam
PF00530 SRCR, 4 hits
PRINTSiPR00258 SPERACTRCPTR
SMARTiView protein in SMART
SM00202 SR, 4 hits
SUPFAMiSSF56487 SSF56487, 4 hits
PROSITEiView protein in PROSITE
PS00420 SRCR_1, 4 hits
PS50287 SRCR_2, 4 hits
ProtoNetiSearch...

Entry informationi

Entry nameiSRB4D_MOUSE
AccessioniPrimary (citable) accession number: A1L0T3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: February 26, 2008
Last modified: November 7, 2018
This is version 87 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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