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UniProtKB - A1JSK7 (IOLG_YERE8)
Protein
Inositol 2-dehydrogenase
Gene
iolG
Organism
Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)
Status
Functioni
Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).
UniRule annotationCatalytic activityi
- EC:1.1.1.18UniRule annotation
GO - Molecular functioni
- inositol 2-dehydrogenase activity Source: UniProtKB-UniRule
- nucleotide binding Source: InterPro
GO - Biological processi
- inositol catabolic process Source: UniProtKB-UniRule
Keywordsi
Molecular function | Oxidoreductase |
Ligand | NAD |
Names & Taxonomyi
Protein namesi | Recommended name: Inositol 2-dehydrogenaseUniRule annotation (EC:1.1.1.18UniRule annotation)Alternative name(s): Myo-inositol 2-dehydrogenaseUniRule annotation Short name: MI 2-dehydrogenaseUniRule annotation |
Gene namesi | Name:iolGUniRule annotation Ordered Locus Names:YE4026 |
Organismi | Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081) |
Taxonomic identifieri | 393305 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Yersiniaceae › Yersinia › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000352599 | 1 – 337 | Inositol 2-dehydrogenaseAdd BLAST | 337 |
Interactioni
Subunit structurei
Homotetramer.
UniRule annotationProtein-protein interaction databases
STRINGi | 393305.YE4026 |
Family & Domainsi
Sequence similaritiesi
Belongs to the Gfo/Idh/MocA family.UniRule annotation
Phylogenomic databases
eggNOGi | COG0673, Bacteria |
HOGENOMi | CLU_023194_0_1_6 |
OMAi | VNCKYGY |
Family and domain databases
HAMAPi | MF_01671, IolG, 1 hit |
InterProi | View protein in InterPro IPR004104, Gfo/Idh/MocA-like_OxRdtase_C IPR000683, Gfo/Idh/MocA-like_OxRdtase_N IPR023794, MI/DCI_dehydrogenase IPR036291, NAD(P)-bd_dom_sf |
Pfami | View protein in Pfam PF01408, GFO_IDH_MocA, 1 hit PF02894, GFO_IDH_MocA_C, 1 hit |
SUPFAMi | SSF51735, SSF51735, 1 hit |
i Sequence
Sequence statusi: Complete.
A1JSK7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSLNIGVIGT GAIGQDHIRR CSKVLQGSRI VAVTDINRES ATKVIRDLGI
60 70 80 90 100
EANVYADGYE VINAKEVEAV LVTSWGPSHE EFVLAAVAAG KYVFCEKPLA
110 120 130 140 150
VTAEGCKRIV EAEAAQGKRL VQVGFMRPYD QGYRALKDVI TSGKIGEPLM
160 170 180 190 200
LHCAHRNPRV GDNYTTSMAI TDTLIHEIDV LRWLLDDDYV SVQVVFPRKA
210 220 230 240 250
KHAKTHLRDP QVVLFETAKG TRIDVEIFVN CQYGYDIQCE VVGDSGIAKL
260 270 280 290 300
PEPSSVLLRS EARLSNEILT DWKDRFIDAY DVELQAFIND VLAEKLTGPS
310 320 330
AWDGFAAAVT ADACIAAQES GQIVPIRLPQ RPDFYDK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AM286415 Genomic DNA Translation: CAL14044.1 |
RefSeqi | WP_011817367.1, NC_008800.1 YP_001008169.1, NC_008800.1 |
Genome annotation databases
EnsemblBacteriai | CAL14044; CAL14044; YE4026 |
KEGGi | yen:YE4026 |
PATRICi | fig|393305.7.peg.4286 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AM286415 Genomic DNA Translation: CAL14044.1 |
RefSeqi | WP_011817367.1, NC_008800.1 YP_001008169.1, NC_008800.1 |
3D structure databases
AlphaFoldDBi | A1JSK7 |
SMRi | A1JSK7 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 393305.YE4026 |
Genome annotation databases
EnsemblBacteriai | CAL14044; CAL14044; YE4026 |
KEGGi | yen:YE4026 |
PATRICi | fig|393305.7.peg.4286 |
Phylogenomic databases
eggNOGi | COG0673, Bacteria |
HOGENOMi | CLU_023194_0_1_6 |
OMAi | VNCKYGY |
Family and domain databases
HAMAPi | MF_01671, IolG, 1 hit |
InterProi | View protein in InterPro IPR004104, Gfo/Idh/MocA-like_OxRdtase_C IPR000683, Gfo/Idh/MocA-like_OxRdtase_N IPR023794, MI/DCI_dehydrogenase IPR036291, NAD(P)-bd_dom_sf |
Pfami | View protein in Pfam PF01408, GFO_IDH_MocA, 1 hit PF02894, GFO_IDH_MocA_C, 1 hit |
SUPFAMi | SSF51735, SSF51735, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | IOLG_YERE8 | |
Accessioni | A1JSK7Primary (citable) accession number: A1JSK7 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 14, 2008 |
Last sequence update: | February 6, 2007 | |
Last modified: | May 25, 2022 | |
This is version 78 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |