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Protein

tRNA pseudouridine synthase D

Gene

truD

Organism
Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(13) = tRNA pseudouridine(13).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei26SubstrateUniRule annotation1
Active sitei79NucleophileUniRule annotation1
Binding sitei128SubstrateUniRule annotation1
Binding sitei328SubstrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase DUniRule annotation (EC:5.4.99.27UniRule annotation)
Alternative name(s):
tRNA pseudouridine(13) synthaseUniRule annotation
tRNA pseudouridylate synthase DUniRule annotation
tRNA-uridine isomerase DUniRule annotation
Gene namesi
Name:truDUniRule annotation
Ordered Locus Names:YE0771
OrganismiYersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)
Taxonomic identifieri393305 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeYersinia
Proteomesi
  • UP000000642 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000847691 – 349tRNA pseudouridine synthase DAdd BLAST349

Proteomic databases

PRIDEiA1JJT6

Interactioni

Protein-protein interaction databases

STRINGi393305.YE0771

Structurei

3D structure databases

ProteinModelPortaliA1JJT6
SMRiA1JJT6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini154 – 302TRUDUniRule annotationAdd BLAST149

Sequence similaritiesi

Belongs to the pseudouridine synthase TruD family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4106NZV Bacteria
COG0585 LUCA
HOGENOMiHOG000224848
KOiK06176
OMAiLWLWVEK
OrthoDBiPOG091H03KK

Family and domain databases

HAMAPiMF_01082 TruD, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR001656 PsdUridine_synth_TruD
IPR020119 PsdUridine_synth_TruD_CS
IPR011760 PsdUridine_synth_TruD_insert
PANTHERiPTHR13326 PTHR13326, 2 hits
PfamiView protein in Pfam
PF01142 TruD, 2 hits
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00094 tRNA_TruD_broad, 1 hit
PROSITEiView protein in PROSITE
PS50984 TRUD, 1 hit
PS01268 UPF0024, 1 hit

Sequencei

Sequence statusi: Complete.

A1JJT6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDMDNLTWLH GKPKASGVLK ANPEDFVVVE DLGFEPDGEG EHLLVRIRKH
60 70 80 90 100
GCNTQFVADY LARFAKIHPR LVSYAGLKDR HAVTEQWFCL HLPGKEAPDL
110 120 130 140 150
STFELEGCEV LESVRQKRKL RIGSLKGNAF TLVLRHITDN QDVEQRLQQI
160 170 180 190 200
AAHGVPNYFG SQRFGRGGNN LVLARLWANN EIRVKERSKR SFYLSASRSA
210 220 230 240 250
MFNLISSDRL AQQQATTVLE GDALQLSGRG SWFVAAADEL ALLQQRVDAG
260 270 280 290 300
ELNITAPLPG DGELGTQGAA LAFEQACLAD QTELLALIKR ERVEGARRAI
310 320 330 340
LLKPQNIAWN WWDEVTLELS FWLPAGSFAT SVVREIMNQD NADAADIAE
Length:349
Mass (Da):38,857
Last modified:February 6, 2007 - v1
Checksum:iFB7ED80443775E81
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM286415 Genomic DNA Translation: CAL10873.1
RefSeqiWP_011815611.1, NC_008800.1
YP_001005112.1, NC_008800.1

Genome annotation databases

EnsemblBacteriaiCAL10873; CAL10873; YE0771
GeneIDi4716121
KEGGiyen:YE0771
PATRICifig|393305.7.peg.864

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM286415 Genomic DNA Translation: CAL10873.1
RefSeqiWP_011815611.1, NC_008800.1
YP_001005112.1, NC_008800.1

3D structure databases

ProteinModelPortaliA1JJT6
SMRiA1JJT6
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi393305.YE0771

Proteomic databases

PRIDEiA1JJT6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAL10873; CAL10873; YE0771
GeneIDi4716121
KEGGiyen:YE0771
PATRICifig|393305.7.peg.864

Phylogenomic databases

eggNOGiENOG4106NZV Bacteria
COG0585 LUCA
HOGENOMiHOG000224848
KOiK06176
OMAiLWLWVEK
OrthoDBiPOG091H03KK

Family and domain databases

HAMAPiMF_01082 TruD, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR001656 PsdUridine_synth_TruD
IPR020119 PsdUridine_synth_TruD_CS
IPR011760 PsdUridine_synth_TruD_insert
PANTHERiPTHR13326 PTHR13326, 2 hits
PfamiView protein in Pfam
PF01142 TruD, 2 hits
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00094 tRNA_TruD_broad, 1 hit
PROSITEiView protein in PROSITE
PS50984 TRUD, 1 hit
PS01268 UPF0024, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiTRUD_YERE8
AccessioniPrimary (citable) accession number: A1JJT6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: February 6, 2007
Last modified: November 7, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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