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Protein
Submitted name:

Alpha 1 antitrypsin

Gene
N/A
Organism
Canis lupus familiaris (Dog) (Canis familiaris)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Protein family/group databases

MEROPSiI04.001

Names & Taxonomyi

Protein namesi
Submitted name:
Alpha 1 antitrypsinImported
OrganismiCanis lupus familiaris (Dog) (Canis familiaris)Imported
Taxonomic identifieri9615 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_500263472425 – 415Sequence analysisAdd BLAST391

Proteomic databases

PRIDEiA1ILJ0

Structurei

3D structure databases

ProteinModelPortaliA1ILJ0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini56 – 412SERPINInterPro annotationAdd BLAST357

Sequence similaritiesi

Belongs to the serpin family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG2392 Eukaryota
COG4826 LUCA
HOGENOMiHOG000238521
HOVERGENiHBG005957

Family and domain databases

InterProiView protein in InterPro
IPR023795 Serpin_CS
IPR023796 Serpin_dom
IPR000215 Serpin_fam
IPR036186 Serpin_sf
PANTHERiPTHR11461 PTHR11461, 1 hit
PfamiView protein in Pfam
PF00079 Serpin, 1 hit
SMARTiView protein in SMART
SM00093 SERPIN, 1 hit
SUPFAMiSSF56574 SSF56574, 1 hit
PROSITEiView protein in PROSITE
PS00284 SERPIN, 1 hit

Sequencei

Sequence statusi: Complete.

A1ILJ0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPSSITWGLL LLAGLCCLVP RSLAEGLQGD AVQETDDPEH QPACHKIAPN
60 70 80 90 100
LADFAFSLYR QVAQESNTTN IFFSPVSIAT AFAMLSLGTK GDTHTQIMQG
110 120 130 140 150
LGFNLTERAE REVHQGFHQL LSILNQPDNQ LQLTTGSGLF INDTIKLLNK
160 170 180 190 200
FLEDVRNLYH SEAFTINFRH TEEAKKQINN YVEKGTQGKI VDLVKDLDED
210 220 230 240 250
TVFALVNYIF FKGKWEKPFE VEHTTEEDFH VDEHTTVKVP MMSRLGMFDI
260 270 280 290 300
QHCATLSSWV LLMEYVGNAT AFFILPDEGK MQHLESKLTK EVLAKFLEKR
310 320 330 340 350
YARSASLRLP KLSISGTYDL KSVLSKMGIT KVFSAEADLS GITEEGPLML
360 370 380 390 400
SKGLHKAVLT IDEKGTEAAG ATFLEAIPMS MPPSVDFNKP FLIIIVDRDT
410
KSPLFMGKVV NPTQK
Length:415
Mass (Da):46,306
Last modified:February 6, 2007 - v1
Checksum:i71D875582E388527
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB287507 mRNA Translation: BAF42652.1
UniGeneiCfa.5989

Similar proteinsi

Entry informationi

Entry nameiA1ILJ0_CANLF
AccessioniPrimary (citable) accession number: A1ILJ0
Entry historyiIntegrated into UniProtKB/TrEMBL: February 6, 2007
Last sequence update: February 6, 2007
Last modified: January 31, 2018
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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