Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

UniProtKB - A1IGV8 (AAGAR_THASX)

Entry version 47 (11 Dec 2019)
Sequence version 1 (06 Feb 2007)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Alpha-agarase

Gene

agaA33

Organism
Thalassotalea agarivorans (Thalassomonas agarivorans)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Alpha-agarase. Hydrolyzes agarose, agarohexaose, neoagarohexaose and porphyran. Hydrolysis of porphyran by this enzyme improves its antioxidant activity. Does not hydrolyze kappa-carrageenan, iota-carrageenen or lambda-carrageenan.2 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the ‘Function’ section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Ca2+1 Publication

<p>This subsection of the ‘Function’ section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>pH dependencei

Optimum pH is 8.5. Active between pH 4.5 and 9.5, stable between pH 6.5 and 10.5.2 Publications

Temperature dependencei

Optimum temperature is 45 degrees Celsius. Stable up to 40 degrees Celsius.2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGlycosidase, Hydrolase
Biological processCarbohydrate metabolism, Polysaccharide degradation
LigandCalcium, Metal-binding

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...BioCyci		MetaCyc:MONOMER-16654

Protein family/group databases

Carbohydrate-Active enZymes

More...CAZyi		CBM6 Carbohydrate-Binding Module Family 6
GH96 Glycoside Hydrolase Family 96

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Alpha-agarase1 Publication (EC:3.2.1.158)
Alternative name(s):
AgaraseA331 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:agaA33Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiThalassotalea agarivorans (Thalassomonas agarivorans)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri349064 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Colwelliaceae › Thalassotalea

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 27Sequence analysisAdd BLAST27
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes a propeptide, which is a part of a protein that is cleaved during maturation or activation. Once cleaved, a propeptide generally has no independent biological function.<p><a href='/help/propep' target='_top'>More...</a></p>PropeptideiPRO_000039792828 – 684Sequence analysis1 PublicationAdd BLAST657
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_0000397929685 – 1463Alpha-agarase1 PublicationAdd BLAST779

Proteomic databases

PRoteomics IDEntifications database

More...PRIDEi		A1IGV8

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Monomer.

1 Publication

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		A1IGV8

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini534 – 677PA14PROSITE-ProRule annotationAdd BLAST144
Domaini701 – 832CBM6PROSITE-ProRule annotationAdd BLAST132

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the glycosyl hydrolase 96 family.By similarity

Keywords - Domaini

Signal

Phylogenomic databases

KEGG Orthology (KO)

More...KOi		K20851

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.60.120.260, 3 hits
4.10.1080.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR006584 Cellulose-bd_IV
IPR005084 CMB_fam6
IPR008979 Galactose-bd-like_sf
IPR037524 PA14/GLEYA
IPR003367 Thrombospondin_3-like_rpt
IPR028974 TSP_type-3_rpt

Pfam protein domain database

More...Pfami		View protein in Pfam
PF03422 CBM_6, 1 hit
PF02412 TSP_3, 6 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00606 CBD_IV, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF103647 SSF103647, 2 hits
SSF49785 SSF49785, 3 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51175 CBM6, 3 hits
PS51820 PA14, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

A1IGV8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MITSSKKIVS AMLSTSLWIG VASAAYAETT NVEAEGYSTI GGTYQDGNPQ 
        60         70         80         90        100
PINIYSVNGV QAINFVNRGD FAEYDVSVST AGEYSIEYLI GTSIASGSAV 
       110        120        130        140        150
EISVLVDGNW QSAGSTNVPL GQWDNFQALA ANNNISLAQG TNRIKITGAG 
       160        170        180        190        200
THDWQWNLDA FSLTLVTPEN PDNPDNPDNP DDGNTGQPGT PFTIEMEAFD 
       210        220        230        240        250
ATGSDDPRAQ GMVIGERGYP EDKHTVVDSN QTTDWVDYNI NFPVSGNYRI 
       260        270        280        290        300
EMLASGQTSH ATAILFVDNV QINEVAVDTG NQAVFLDFEL TDSTYISAGA 
       310        320        330        340        350
HTIRVQSGSQ INEFSWMWFG DALTFTPLDG GSTDGDADND GVLDSVDTCP 
       360        370        380        390        400
NTPAGAQVDA NGCEIIVDND TDNDGVDNSI DQCPNTPAGA QVDANGCEIV 
       410        420        430        440        450
AVVDADNDGV EDSLDMCPNT PAGAPVNGQG CADSQLDADN DGVSDDIDQC 
       460        470        480        490        500
PSTPAGSVVD GTGCIVVTPP ADSDNDGVVD TLDMCPNTAA GLTVDSQGCA 
       510        520        530        540        550
LSQLDSDNDG VTDDIDQCAN TPSGETANAT GCSSSQEGGG TDPDTPQPGL 
       560        570        580        590        600
LYGELAGAMN VSDTNPNWER TTDLLQTEDS VKGNTTEVYT GFIYDADGHI 
       610        620        630        640        650
SFYEHIDDSV RLYIDGVLVL SNDSWEASSQ TTDLNLTPGT HEIELRIGNA 
       660        670        680        690        700
DGGSGAVDGI GFGIDVDGGT NFVHPSTLSE SIFTSVGEET GNPDLEQEGD 
       710        720        730        740        750
IIVELESFVF TSTNGRVGSD SVEGFSPTAT GVNWVTNGDY GDYMVTFEEP 
       760        770        780        790        800
GTYGAYITIS AANDGSYGAR VDVDGWPVAW GYFGGTGSWD VSSENLLYGG 
       810        820        830        840        850
TFVVEQAGEK VVRVEAIGGS DWQWSGDRVR FTRLGDVTAI PSPIYNPDDH 
       860        870        880        890        900
FVAEIQGPQT DVTYLKKPVE IPANKKVLKS DVWYTYPQNR ELEGYDNFGA 
       910        920        930        940        950
TGAFWGHPPE HDFYDDTVIM DWAVDAVYAF QAEGYEYTAR GEFDWGYGWF 
       960        970        980        990       1000
TEYTTNPQPH YVRTLDDRNV RMTFMGYLSH DGYNNNWLSN HSPAFVPFMK 
      1010       1020       1030       1040       1050
SQVDQILKAN PDKLMFDTQT NSTRSTDMRD FGGDFSPYAM ENFRVWLSKK 
      1060       1070       1080       1090       1100
YSTGELAALG INDINSFDYG DFLRAQGVTH TSWSNAGDTL SGNIPLQEDY 
      1110       1120       1130       1140       1150
IYFNRDVWNQ KFAEVLDYIR QQQPDIEIGA STHLFESRGY VFNENLTFLS 
      1160       1170       1180       1190       1200
GELNLGARTT ISELPTNILV HLKGAQAVDK TLVYFPYPWE FDELRLQDAP 
      1210       1220       1230       1240       1250
RFGRGWVAQA YAYGGLFSIP ANVWVGGEVW TWSPGADNYR DIYLFVRAQA 
      1260       1270       1280       1290       1300
DLLDDYTSYS KVGLVHAMYS SMKAGFIDGG NQIQSSTKLL TEGNINFDLL 
      1310       1320       1330       1340       1350
VFGDEGYPVV PRPEDFDKFD HIFFDGDEQY LTAEQQALLD QQGDKVRHIG 
      1360       1370       1380       1390       1400
QRGTVSGIEI TVSISGTESN ETVSAVSRIH ETDAAAPYVV HLVNRPFAGG 
      1410       1420       1430       1440       1450
VTPTLNNVEV AIPQSYFPEV VTGATLHLPD GTSTSLTLST NADGDVVLPV 
      1460 
NNLEVWGILE LAH
Length:1,463
Mass (Da):158,250
Last modified:February 6, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iADCB23F68C299BEC
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AB211981 Genomic DNA Translation: BAF44076.1

Genome annotation databases

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		ag:BAF44076

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB211981 Genomic DNA Translation: BAF44076.1

3D structure databases

SMRiA1IGV8
ModBaseiSearch...

Protein family/group databases

CAZyiCBM6 Carbohydrate-Binding Module Family 6
GH96 Glycoside Hydrolase Family 96

Proteomic databases

PRIDEiA1IGV8

Genome annotation databases

KEGGiag:BAF44076

Phylogenomic databases

KOiK20851

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-16654

Family and domain databases

Gene3Di2.60.120.260, 3 hits
4.10.1080.10, 1 hit
InterProiView protein in InterPro
IPR006584 Cellulose-bd_IV
IPR005084 CMB_fam6
IPR008979 Galactose-bd-like_sf
IPR037524 PA14/GLEYA
IPR003367 Thrombospondin_3-like_rpt
IPR028974 TSP_type-3_rpt
PfamiView protein in Pfam
PF03422 CBM_6, 1 hit
PF02412 TSP_3, 6 hits
SMARTiView protein in SMART
SM00606 CBD_IV, 1 hit
SUPFAMiSSF103647 SSF103647, 2 hits
SSF49785 SSF49785, 3 hits
PROSITEiView protein in PROSITE
PS51175 CBM6, 3 hits
PS51820 PA14, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiAAGAR_THASX
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A1IGV8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 5, 2010
Last sequence update: February 6, 2007
Last modified: December 11, 2019
This is version 47 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again