UniProtKB - A1DGC8 (A1DGC8_NEOFI)
Protein
Tubulin-specific chaperone A
Gene
NFIA_083870
Organism
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus)
Status
Functioni
GO - Molecular functioni
- beta-tubulin binding Source: InterPro
GO - Biological processi
- post-chaperonin tubulin folding pathway Source: UniProtKB-UniRule
- tubulin complex assembly Source: UniProtKB-UniRule
Keywordsi
Molecular function | ChaperoneUniRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Tubulin-specific chaperone AUniRule annotation |
Gene namesi | ORF Names:NFIA_083870Imported |
Organismi | Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus)Imported |
Taxonomic identifieri | 331117 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Aspergillaceae › Aspergillus › Aspergillus subgen. Fumigati › |
Proteomesi |
|
Organism-specific databases
EuPathDBi | FungiDB:NFIA_083870 |
Subcellular locationi
Cytoskeleton
- cytoskeleton UniRule annotation
Cytoskeleton
- microtubule Source: UniProtKB-KW
Other locations
- cytoplasm Source: UniProtKB-KW
Keywords - Cellular componenti
Cytoplasm, CytoskeletonUniRule annotation, MicrotubuleUniRule annotationInteractioni
Subunit structurei
Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.
UniRule annotationGO - Molecular functioni
- beta-tubulin binding Source: InterPro
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 28 – 49 | DisorderedSequence analysisAdd BLAST | 22 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 60 – 87 | Sequence analysisAdd BLAST | 28 |
Sequence similaritiesi
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
eggNOGi | ENOG502SH35, Eukaryota |
HOGENOMi | CLU_130569_0_0_1 |
OMAi | DENREYM |
OrthoDBi | 1471374at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR004226, TBCA IPR036126, TBCA_sf |
PANTHERi | PTHR21500, PTHR21500, 1 hit |
Pfami | View protein in Pfam PF02970, TBCA, 1 hit |
SUPFAMi | SSF46988, SSF46988, 1 hit |
i Sequence
Sequence statusi: Complete.
A1DGC8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAPRSQLEIA TSSVERLVKE EASYHRELQQ QTERIQKLES QEPGEDENRE
60 70 80 90 100
YMLKQERLAL EETKKVLPSL KQKIDEAVAK LESLLAEEGK KGPESNVEQI
110
TAGKEAIAKA KTAKREIA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | DS027696 Genomic DNA Translation: EAW18435.1 |
RefSeqi | XP_001260332.1, XM_001260331.1 |
Genome annotation databases
EnsemblFungii | EAW18435; EAW18435; NFIA_083870 |
GeneIDi | 4586890 |
KEGGi | nfi:NFIA_083870 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | DS027696 Genomic DNA Translation: EAW18435.1 |
RefSeqi | XP_001260332.1, XM_001260331.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
EnsemblFungii | EAW18435; EAW18435; NFIA_083870 |
GeneIDi | 4586890 |
KEGGi | nfi:NFIA_083870 |
Organism-specific databases
EuPathDBi | FungiDB:NFIA_083870 |
Phylogenomic databases
eggNOGi | ENOG502SH35, Eukaryota |
HOGENOMi | CLU_130569_0_0_1 |
OMAi | DENREYM |
OrthoDBi | 1471374at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR004226, TBCA IPR036126, TBCA_sf |
PANTHERi | PTHR21500, PTHR21500, 1 hit |
Pfami | View protein in Pfam PF02970, TBCA, 1 hit |
SUPFAMi | SSF46988, SSF46988, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A1DGC8_NEOFI | |
Accessioni | A1DGC8Primary (citable) accession number: A1DGC8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | January 23, 2007 |
Last sequence update: | January 23, 2007 | |
Last modified: | December 2, 2020 | |
This is version 66 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |