UniProtKB - A1DFA8 (BGLI_NEOFI)
Protein
Probable beta-glucosidase I
Gene
bglI
Organism
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus)
Status
Functioni
Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).By similarity
Catalytic activityi
- Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose. EC:3.2.1.21
: cellulose degradation Pathwayi
This protein is involved in the pathway cellulose degradation, which is part of Glycan metabolism.View all proteins of this organism that are known to be involved in the pathway cellulose degradation and in Glycan metabolism.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 225 | By similarity | 1 |
GO - Molecular functioni
- beta-glucosidase activity Source: UniProtKB-EC
- scopolin beta-glucosidase activity Source: UniProtKB-EC
GO - Biological processi
- cellulose catabolic process Source: UniProtKB-UniPathway
Keywordsi
Molecular function | Glycosidase, Hydrolase |
Biological process | Carbohydrate metabolism, Cellulose degradation, Polysaccharide degradation |
Enzyme and pathway databases
UniPathwayi | UPA00696 |
Names & Taxonomyi
Protein namesi | Recommended name: Probable beta-glucosidase I (EC:3.2.1.21)Alternative name(s): Beta-D-glucoside glucohydrolase I Cellobiase I Gentiobiase I |
Gene namesi | Name:bglI ORF Names:NFIA_080070 |
Organismi | Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus) |
Taxonomic identifieri | 331117 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Aspergillaceae › Aspergillus › Aspergillus subgen. Fumigati › |
Proteomesi |
|
Organism-specific databases
VEuPathDBi | FungiDB:NFIA_080070 |
Subcellular locationi
Extracellular region or secreted
- Secreted By similarity
Extracellular region or secreted
- extracellular region Source: UniProtKB-SubCell
Keywords - Cellular componenti
SecretedPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000394891 | 1 – 838 | Probable beta-glucosidase IAdd BLAST | 838 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 197 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 493 | N-linked (GlcNAc...) asparagineSequence analysis | 1 |
Keywords - PTMi
GlycoproteinFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 395 – 555 | PA14PROSITE-ProRule annotationAdd BLAST | 161 |
Sequence similaritiesi
Belongs to the glycosyl hydrolase 3 family.Curated
Phylogenomic databases
eggNOGi | ENOG502QR4D, Eukaryota |
HOGENOMi | CLU_004542_4_0_1 |
OMAi | ACFPCAT |
OrthoDBi | 175854at2759 |
Family and domain databases
Gene3Di | 2.60.120.260, 1 hit 2.60.40.10, 1 hit 3.20.20.300, 1 hit 3.40.50.1700, 1 hit |
InterProi | View protein in InterPro IPR026891, Fn3-like IPR008979, Galactose-bd-like_sf IPR019800, Glyco_hydro_3_AS IPR002772, Glyco_hydro_3_C IPR036881, Glyco_hydro_3_C_sf IPR001764, Glyco_hydro_3_N IPR036962, Glyco_hydro_3_N_sf IPR017853, Glycoside_hydrolase_SF IPR013783, Ig-like_fold IPR037524, PA14/GLEYA IPR011658, PA14_dom |
Pfami | View protein in Pfam PF14310, Fn3-like, 1 hit PF00933, Glyco_hydro_3, 1 hit PF01915, Glyco_hydro_3_C, 1 hit PF07691, PA14, 1 hit |
PRINTSi | PR00133, GLHYDRLASE3 |
SMARTi | View protein in SMART SM01217, Fn3_like, 1 hit SM00758, PA14, 1 hit |
SUPFAMi | SSF51445, SSF51445, 1 hit SSF52279, SSF52279, 1 hit |
PROSITEi | View protein in PROSITE PS00775, GLYCOSYL_HYDROL_F3, 1 hit PS51820, PA14, 1 hit |
i Sequence
Sequence statusi: Complete.
A1DFA8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MVQLDVEKTI EELTLGEKVA LTAGIDFWHT AAVPRLNIPS LRLSDGPNGV
60 70 80 90 100
RGTRFFNGVP AACFPCATAL GATWDTKLLH EVGRLMGEES IAKGTHVVLG
110 120 130 140 150
PTINIQRSPL GGRGFESFAE DGVLSGILAG HYCKGLQETG VAATLKHFVC
160 170 180 190 200
NDQEHERLAV DSIVTMRAMR EIYLLPFQLA MRICKTACVM TAYNKINGTH
210 220 230 240 250
VSENKQIITD ILRKEWGWDG LVMSDWFGTY STSDAINAGL DLEMPGPTRW
260 270 280 290 300
RGTALAHAVS SNKAFEFVVD ERVRNILNLH NFVEPLGIPE NAPEKALNRP
310 320 330 340 350
EDQALLRRAA AESVVLMKNQ DNILPLKKEK PILVIGPNAK TAAYCGGGSA
360 370 380 390 400
SLDAYYTVTP FEGVSAQSQG EVKFSQGVYS YKELPLLGPL LKTDDGKKGF
410 420 430 440 450
KFRVYNEPPS EPNRQLIDEL HLESSSGFLM DYKHPKIKTF TFYVDMEGYF
460 470 480 490 500
TPEEDGIYDF GVTVVGTGKL FVDDELVVDN SKNQRQGTAM FGNATVEEKG
510 520 530 540 550
SKELKAGQTY KVVLQFGTAP TSDLDMRGVV IFGPGGFRFG AARRVSQEEL
560 570 580 590 600
ISKAAELASQ ASQVVIFAGL TSEWETEGHD RDHMDLPPGS DEMISRVLDA
610 620 630 640 650
NPNAVVVIQS GTPVTMPWAH KAKALLQAWF GGNECGNGIA DVLYGAVNPA
660 670 680 690 700
AKLPLSFPVR LQDNPSYLNF RSERGRVLYG EDVYVGYRYY EKVDLAPLFP
710 720 730 740 750
FGHGLSYTTF SRSDLSLATT PEKPQLEDGE PITATVSVTN TGSVAGAEIV
760 770 780 790 800
QLWVAPPPTG VNRPVRELKG FAKVFLQPGE TKKVEIVVEK KLATSWWDEQ
810 820 830
REKWASEKGT YEVLVTGTGD EVLKTSFEVG KTRYWLGL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | DS027696 Genomic DNA Translation: EAW18065.1 |
RefSeqi | XP_001259962.1, XM_001259961.1 |
Genome annotation databases
EnsemblFungii | EAW18065; EAW18065; NFIA_080070 |
GeneIDi | 4586518 |
KEGGi | nfi:NFIA_080070 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | DS027696 Genomic DNA Translation: EAW18065.1 |
RefSeqi | XP_001259962.1, XM_001259961.1 |
3D structure databases
SMRi | A1DFA8 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 36630.CADNFIAP00006674 |
Genome annotation databases
EnsemblFungii | EAW18065; EAW18065; NFIA_080070 |
GeneIDi | 4586518 |
KEGGi | nfi:NFIA_080070 |
Organism-specific databases
VEuPathDBi | FungiDB:NFIA_080070 |
Phylogenomic databases
eggNOGi | ENOG502QR4D, Eukaryota |
HOGENOMi | CLU_004542_4_0_1 |
OMAi | ACFPCAT |
OrthoDBi | 175854at2759 |
Enzyme and pathway databases
UniPathwayi | UPA00696 |
Family and domain databases
Gene3Di | 2.60.120.260, 1 hit 2.60.40.10, 1 hit 3.20.20.300, 1 hit 3.40.50.1700, 1 hit |
InterProi | View protein in InterPro IPR026891, Fn3-like IPR008979, Galactose-bd-like_sf IPR019800, Glyco_hydro_3_AS IPR002772, Glyco_hydro_3_C IPR036881, Glyco_hydro_3_C_sf IPR001764, Glyco_hydro_3_N IPR036962, Glyco_hydro_3_N_sf IPR017853, Glycoside_hydrolase_SF IPR013783, Ig-like_fold IPR037524, PA14/GLEYA IPR011658, PA14_dom |
Pfami | View protein in Pfam PF14310, Fn3-like, 1 hit PF00933, Glyco_hydro_3, 1 hit PF01915, Glyco_hydro_3_C, 1 hit PF07691, PA14, 1 hit |
PRINTSi | PR00133, GLHYDRLASE3 |
SMARTi | View protein in SMART SM01217, Fn3_like, 1 hit SM00758, PA14, 1 hit |
SUPFAMi | SSF51445, SSF51445, 1 hit SSF52279, SSF52279, 1 hit |
PROSITEi | View protein in PROSITE PS00775, GLYCOSYL_HYDROL_F3, 1 hit PS51820, PA14, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | BGLI_NEOFI | |
Accessioni | A1DFA8Primary (citable) accession number: A1DFA8 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 15, 2010 |
Last sequence update: | January 23, 2007 | |
Last modified: | February 10, 2021 | |
This is version 82 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Glycosyl hydrolases
Classification of glycosyl hydrolase families and list of entries - PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families