bglI

Functionⁱ

Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).By similarity

Catalytic activityⁱ

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

Pathwayⁱ: cellulose degradation

This protein is involved in the pathway cellulose degradation, which is part of Glycan metabolism.
View all proteins of this organism that are known to be involved in the pathway cellulose degradation and in Glycan metabolism.

Sites

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Active siteⁱ	225	By similarity		1

GO - Molecular functionⁱ

beta-glucosidase activity Source: UniProtKB-EC
scopolin beta-glucosidase activity Source: UniProtKB-EC

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

cellulose catabolic process Source: UniProtKB-UniPathway

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Glycosidase, Hydrolase
Biological process	Carbohydrate metabolism, Cellulose degradation, Polysaccharide degradation

Enzyme and pathway databases

UniPathwayⁱ	UPA00696

UniPathwayⁱ

UPA00696

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Probable beta-glucosidase I (EC:3.2.1.21) Alternative name(s): Beta-D-glucoside glucohydrolase I Cellobiase I Gentiobiase I
Gene namesⁱ	Name:bglI ORF Names:NFIA_080070
Organismⁱ	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus)
Taxonomic identifierⁱ	331117 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Pezizomycotina › leotiomyceta › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Aspergillaceae › Aspergillus › Aspergillus fischeri
Proteomesⁱ	UP000006702 Componentⁱ: Unassembled WGS sequence

Organism-specific databases

EuPathDBⁱ	FungiDB:NFIA_080070

EuPathDBⁱ

FungiDB:NFIA_080070

Keywords - Cellular componentⁱ

Secreted

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000394891	1 – 838	Probable beta-glucosidase IAdd BLAST		838

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Glycosylationⁱ	197	N-linked (GlcNAc...) asparagineSequence analysis		1
Glycosylationⁱ	493	N-linked (GlcNAc...) asparagineSequence analysis		1

Keywords - PTMⁱ

Glycoprotein

Proteomic databases

PRIDEⁱ	A1DFA8

PRIDEⁱ

A1DFA8

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	36630.CADNFIAP00006674

STRINGⁱ

36630.CADNFIAP00006674

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	A1DFA8
SMRⁱ	A1DFA8
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	395 – 555	PA14PROSITE-ProRule annotationAdd BLAST		161

Sequence similaritiesⁱ

Belongs to the glycosyl hydrolase 3 family.Curated

Phylogenomic databases

HOGENOMⁱ	HOG000031215
KEGG Orthology (KO) More...KOⁱ	K05349
OMAⁱ	KLATSWW
Database of Orthologous Groups More...OrthoDBⁱ	EOG092C0SKR

Family and domain databases

Gene3Dⁱ	2.60.120.260, 1 hit 2.60.40.10, 1 hit 3.20.20.300, 2 hits 3.40.50.1700, 2 hits
InterProⁱ	View protein in InterPro IPR026891 Fn3-like IPR008979 Galactose-bd-like_sf IPR019800 Glyco_hydro_3_AS IPR002772 Glyco_hydro_3_C IPR036881 Glyco_hydro_3_C_sf IPR001764 Glyco_hydro_3_N IPR036962 Glyco_hydro_3_N_sf IPR017853 Glycoside_hydrolase_SF IPR013783 Ig-like_fold IPR037524 PA14/GLEYA IPR011658 PA14_dom
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF14310 Fn3-like, 1 hit PF00933 Glyco_hydro_3, 1 hit PF01915 Glyco_hydro_3_C, 1 hit PF07691 PA14, 1 hit
PRINTSⁱ	PR00133 GLHYDRLASE3
SMARTⁱ	View protein in SMART SM01217 Fn3_like, 1 hit SM00758 PA14, 1 hit
SUPFAMⁱ	SSF51445 SSF51445, 1 hit SSF52279 SSF52279, 2 hits
PROSITEⁱ	View protein in PROSITE PS00775 GLYCOSYL_HYDROL_F3, 1 hit PS51820 PA14, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

A1DFA8-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MVQLDVEKTI EELTLGEKVA LTAGIDFWHT AAVPRLNIPS LRLSDGPNGV 
        60         70         80         90        100
RGTRFFNGVP AACFPCATAL GATWDTKLLH EVGRLMGEES IAKGTHVVLG 
       110        120        130        140        150
PTINIQRSPL GGRGFESFAE DGVLSGILAG HYCKGLQETG VAATLKHFVC 
       160        170        180        190        200
NDQEHERLAV DSIVTMRAMR EIYLLPFQLA MRICKTACVM TAYNKINGTH 
       210        220        230        240        250
VSENKQIITD ILRKEWGWDG LVMSDWFGTY STSDAINAGL DLEMPGPTRW 
       260        270        280        290        300
RGTALAHAVS SNKAFEFVVD ERVRNILNLH NFVEPLGIPE NAPEKALNRP 
       310        320        330        340        350
EDQALLRRAA AESVVLMKNQ DNILPLKKEK PILVIGPNAK TAAYCGGGSA 
       360        370        380        390        400
SLDAYYTVTP FEGVSAQSQG EVKFSQGVYS YKELPLLGPL LKTDDGKKGF 
       410        420        430        440        450
KFRVYNEPPS EPNRQLIDEL HLESSSGFLM DYKHPKIKTF TFYVDMEGYF 
       460        470        480        490        500
TPEEDGIYDF GVTVVGTGKL FVDDELVVDN SKNQRQGTAM FGNATVEEKG 
       510        520        530        540        550
SKELKAGQTY KVVLQFGTAP TSDLDMRGVV IFGPGGFRFG AARRVSQEEL 
       560        570        580        590        600
ISKAAELASQ ASQVVIFAGL TSEWETEGHD RDHMDLPPGS DEMISRVLDA 
       610        620        630        640        650
NPNAVVVIQS GTPVTMPWAH KAKALLQAWF GGNECGNGIA DVLYGAVNPA 
       660        670        680        690        700
AKLPLSFPVR LQDNPSYLNF RSERGRVLYG EDVYVGYRYY EKVDLAPLFP 
       710        720        730        740        750
FGHGLSYTTF SRSDLSLATT PEKPQLEDGE PITATVSVTN TGSVAGAEIV 
       760        770        780        790        800
QLWVAPPPTG VNRPVRELKG FAKVFLQPGE TKKVEIVVEK KLATSWWDEQ 
       810        820        830 
REKWASEKGT YEVLVTGTGD EVLKTSFEVG KTRYWLGL

Length:838

Mass (Da):91,973

Last modified:January 23, 2007 - v1

Checksum:ⁱ4023757A8C6017FF

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	DS027696 Genomic DNA Translation: EAW18065.1
NCBI Reference Sequences More...RefSeqⁱ	XP_001259962.1, XM_001259961.1

Genome annotation databases

EnsemblFungiⁱ	EAW18065; EAW18065; NFIA_080070
GeneIDⁱ	4586518
KEGGⁱ	nfi:NFIA_080070

Similar proteinsⁱ

90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length
A1DFA8	Probable beta-glucosidase I		ASPCL		838
Probable beta-glucosidase I		ASPFC		838
Beta-glucosidase		ASPFM		838
Beta-glucosidase		Aspergillus fumigatus Z5		838
Beta-glucosidase		Aspergillus thermomutatus		838
+2

Protein	Similar proteins		Species	Score	Length
A1DFA8	Probable beta-glucosidase I		EMENI		839
Probable beta-glucosidase I		ASPTN		839
Beta-glucosidase		Phialophora attae		1025
Beta-glucosidase		GAGT3		843
Beta-glucosidase		MARBU		838
+188

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	DS027696 Genomic DNA Translation: EAW18065.1
NCBI Reference Sequences More...RefSeqⁱ	XP_001259962.1, XM_001259961.1

3D structure databases

ProteinModelPortalⁱ	A1DFA8
SMRⁱ	A1DFA8
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	36630.CADNFIAP00006674

STRINGⁱ

36630.CADNFIAP00006674

Proteomic databases

PRIDEⁱ	A1DFA8

PRIDEⁱ

A1DFA8

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblFungiⁱ	EAW18065; EAW18065; NFIA_080070
GeneIDⁱ	4586518
KEGGⁱ	nfi:NFIA_080070

Organism-specific databases

EuPathDBⁱ	FungiDB:NFIA_080070

EuPathDBⁱ

FungiDB:NFIA_080070

Phylogenomic databases

HOGENOMⁱ	HOG000031215
KEGG Orthology (KO) More...KOⁱ	K05349
OMAⁱ	KLATSWW
Database of Orthologous Groups More...OrthoDBⁱ	EOG092C0SKR

Enzyme and pathway databases

UniPathwayⁱ	UPA00696

UniPathwayⁱ

UPA00696

Family and domain databases

Gene3Dⁱ	2.60.120.260, 1 hit 2.60.40.10, 1 hit 3.20.20.300, 2 hits 3.40.50.1700, 2 hits
InterProⁱ	View protein in InterPro IPR026891 Fn3-like IPR008979 Galactose-bd-like_sf IPR019800 Glyco_hydro_3_AS IPR002772 Glyco_hydro_3_C IPR036881 Glyco_hydro_3_C_sf IPR001764 Glyco_hydro_3_N IPR036962 Glyco_hydro_3_N_sf IPR017853 Glycoside_hydrolase_SF IPR013783 Ig-like_fold IPR037524 PA14/GLEYA IPR011658 PA14_dom
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF14310 Fn3-like, 1 hit PF00933 Glyco_hydro_3, 1 hit PF01915 Glyco_hydro_3_C, 1 hit PF07691 PA14, 1 hit
PRINTSⁱ	PR00133 GLHYDRLASE3
SMARTⁱ	View protein in SMART SM01217 Fn3_like, 1 hit SM00758 PA14, 1 hit
SUPFAMⁱ	SSF51445 SSF51445, 1 hit SSF52279 SSF52279, 2 hits
PROSITEⁱ	View protein in PROSITE PS00775 GLYCOSYL_HYDROL_F3, 1 hit PS51820 PA14, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	BGLI_NEOFI
Accessionⁱ	A1DFA8Primary (citable) accession number: A1DFA8
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	June 15, 2010
	Last sequence update:	January 23, 2007
	Last modified:	June 20, 2018
	This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Fungal Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

Glycosyl hydrolases
Classification of glycosyl hydrolase families and list of entries
PATHWAY comments
Index of metabolic and biosynthesis pathways
SIMILARITY comments
Index of protein domains and families

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - A1DFA8 (BGLI_NEOFI)

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Probable beta-glucosidase I

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: cellulose degradation

Sites

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted

Extracellular region or secreted

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Proteomic databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

UniProt is an ELIXIR core data resource

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Functionⁱ

Pathwayⁱ: cellulose degradation

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

PTM / Processingⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ