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Protein

Mitochondrial import inner membrane translocase subunit TIM44

Gene

NFIA_015780

Organism
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processProtein transport, TranslocationUniRule annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Mitochondrial import inner membrane translocase subunit TIM44UniRule annotation
Gene namesi
ORF Names:NFIA_015780Imported
OrganismiNeosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus)Imported
Taxonomic identifieri331117 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000006702 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:NFIA_015780

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membraneUniRule annotation

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi36630.CADNFIAP00002127

Structurei

3D structure databases

ProteinModelPortaliA1D392
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini349 – 503Tim44InterPro annotationAdd BLAST155

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili252 – 272Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the Tim44 family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

HOGENOMiHOG000208172
KOiK17804
OMAiRFLKQCE
OrthoDBiEOG092C2GAN

Family and domain databases

InterProiView protein in InterPro
IPR032710 NTF2-like_dom_sf
IPR017303 Tim44
IPR039544 Tim44-like
IPR007379 Tim44-like_dom
PANTHERiPTHR10721 PTHR10721, 1 hit
PfamiView protein in Pfam
PF04280 Tim44, 1 hit
PIRSFiPIRSF037871 TIM44, 1 hit
SMARTiView protein in SMART
SM00978 Tim44, 1 hit
SUPFAMiSSF54427 SSF54427, 1 hit

Sequencei

Sequence statusi: Complete.

A1D392-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSAVARAATL RSHVPGLRTT YGNAIASSRT LIQNSAYSTS ISTSPTVLQR
60 70 80 90 100
QQSSLPTGVQ LISPYTVLPL TRSFHIATAR WQQQQKEKQS EEQKSEKSEE
110 120 130 140 150
AKSEGDKEEG QKEAPPPPPP HGDKTPWQVF RETLQAEFKA SKEWNESTKA
160 170 180 190 200
LASSAHEFAE NENVKRARAA YEAASGAATS KTSAALKKTG QAIGKGAAWT
210 220 230 240 250
WETPVVKGIR KGVSATGAGL EKATRPVRET EAYKNVKEAI DDGSSSRYGG
260 270 280 290 300
WIEKEERRRQ RQLREQKEMM KSGRRSAEPL VEDPNAGTNL TLHKDSAWKE
310 320 330 340 350
SWREFKDSNP MMQKLFALKE TYNESENPLI STARSISDRV ASFFAENETA
360 370 380 390 400
QVIKKFREMD PNFQMESFLR EMREYILPEV LDAYVKGDIE TLKLWLSDAQ
410 420 430 440 450
FHVYAALSKQ YTTAGLKSDG RILDIRGVDV SHARMLEPGE IPVFVVTCRT
460 470 480 490 500
QEVHVYRNVK TGELAAGMED KVQLVTYAIG LTRIPEDVNN PETRGWRLIE

LQKAARDYI
Length:509
Mass (Da):57,075
Last modified:January 23, 2007 - v1
Checksum:i8F7313E6286DF754
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS027688 Genomic DNA Translation: EAW22885.1
RefSeqiXP_001264782.1, XM_001264781.1

Genome annotation databases

EnsemblFungiiEAW22885; EAW22885; NFIA_015780
GeneIDi4591546
KEGGinfi:NFIA_015780

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS027688 Genomic DNA Translation: EAW22885.1
RefSeqiXP_001264782.1, XM_001264781.1

3D structure databases

ProteinModelPortaliA1D392
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi36630.CADNFIAP00002127

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiEAW22885; EAW22885; NFIA_015780
GeneIDi4591546
KEGGinfi:NFIA_015780

Organism-specific databases

EuPathDBiFungiDB:NFIA_015780

Phylogenomic databases

HOGENOMiHOG000208172
KOiK17804
OMAiRFLKQCE
OrthoDBiEOG092C2GAN

Family and domain databases

InterProiView protein in InterPro
IPR032710 NTF2-like_dom_sf
IPR017303 Tim44
IPR039544 Tim44-like
IPR007379 Tim44-like_dom
PANTHERiPTHR10721 PTHR10721, 1 hit
PfamiView protein in Pfam
PF04280 Tim44, 1 hit
PIRSFiPIRSF037871 TIM44, 1 hit
SMARTiView protein in SMART
SM00978 Tim44, 1 hit
SUPFAMiSSF54427 SSF54427, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA1D392_NEOFI
AccessioniPrimary (citable) accession number: A1D392
Entry historyiIntegrated into UniProtKB/TrEMBL: January 23, 2007
Last sequence update: January 23, 2007
Last modified: November 7, 2018
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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