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Protein

Mitochondrial import inner membrane translocase subunit TIM44

Gene

ACLA_025660

Organism
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processProtein transport, TranslocationUniRule annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Mitochondrial import inner membrane translocase subunit TIM44UniRule annotation
Gene namesi
ORF Names:ACLA_025660Imported
OrganismiAspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)Imported
Taxonomic identifieri344612 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000006701 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:ACLA_025660

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membraneUniRule annotation

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi5057.CADACLAP00002109

Structurei

3D structure databases

ProteinModelPortaliA1CQC8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini352 – 506Tim44InterPro annotationAdd BLAST155

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili256 – 276Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the Tim44 family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

HOGENOMiHOG000208172
KOiK17804
OMAiRFLKQCE
OrthoDBiEOG092C2GAN

Family and domain databases

InterProiView protein in InterPro
IPR032710 NTF2-like_dom_sf
IPR017303 Tim44
IPR039544 Tim44-like
IPR007379 Tim44-like_dom
PANTHERiPTHR10721 PTHR10721, 1 hit
PfamiView protein in Pfam
PF04280 Tim44, 1 hit
PIRSFiPIRSF037871 TIM44, 1 hit
SMARTiView protein in SMART
SM00978 Tim44, 1 hit
SUPFAMiSSF54427 SSF54427, 1 hit

Sequencei

Sequence statusi: Complete.

A1CQC8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSAIARAATI RAQVPGLKAT YGNAIASPRA LFQSGSYSTL PSTSFTSQNN
60 70 80 90 100
RTTLSQPFRL VSPYTALPLT RSFHGAAARW QQQQKEKPTE EKQSEGASRE
110 120 130 140 150
KGEEAKDEGS KEEGQKETPP PPPPHGDKTP WQVFRETLQS EFKASKEWNE
160 170 180 190 200
STKALASSAH QFAENENVKR ARAAYEAASG AATSKTSSAL KTTGHAIGKG
210 220 230 240 250
ATWTWNTPVV KGIRKGVNVT GAGLEKATRP VRETEAYKNV KEAIDDGSSS
260 270 280 290 300
RYGGWIEKEE RRRQRQLREE KELQSGRRRA EPMAEDPNAG TNVTLHKDAA
310 320 330 340 350
WKESWRDFKD SNPMMQKLFA LKETYNESEN PLISTARSIS DRVAGFFAEN
360 370 380 390 400
ETAQVIKKFR EMDPNFQMES FLREMREYIL PEVLDAYVKG DVETLKLWLS
410 420 430 440 450
DAQFHVYAAL SKQYTTAGLK SDGRILDIRG VDVSNARMLE PGEIPVFVVT
460 470 480 490 500
CRTQEVHVYR NVKSGELAAG MEDKVQLVTY AIGLTRIPED VNNPETRGWR
510
LIELQKAARD YI
Length:512
Mass (Da):57,271
Last modified:January 23, 2007 - v1
Checksum:iB3CF6E62DF8E7438
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS027059 Genomic DNA Translation: EAW07849.1
RefSeqiXP_001269275.1, XM_001269274.1

Genome annotation databases

EnsemblFungiiEAW07849; EAW07849; ACLA_025660
GeneIDi4702035
KEGGiact:ACLA_025660

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS027059 Genomic DNA Translation: EAW07849.1
RefSeqiXP_001269275.1, XM_001269274.1

3D structure databases

ProteinModelPortaliA1CQC8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi5057.CADACLAP00002109

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiEAW07849; EAW07849; ACLA_025660
GeneIDi4702035
KEGGiact:ACLA_025660

Organism-specific databases

EuPathDBiFungiDB:ACLA_025660

Phylogenomic databases

HOGENOMiHOG000208172
KOiK17804
OMAiRFLKQCE
OrthoDBiEOG092C2GAN

Family and domain databases

InterProiView protein in InterPro
IPR032710 NTF2-like_dom_sf
IPR017303 Tim44
IPR039544 Tim44-like
IPR007379 Tim44-like_dom
PANTHERiPTHR10721 PTHR10721, 1 hit
PfamiView protein in Pfam
PF04280 Tim44, 1 hit
PIRSFiPIRSF037871 TIM44, 1 hit
SMARTiView protein in SMART
SM00978 Tim44, 1 hit
SUPFAMiSSF54427 SSF54427, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA1CQC8_ASPCL
AccessioniPrimary (citable) accession number: A1CQC8
Entry historyiIntegrated into UniProtKB/TrEMBL: January 23, 2007
Last sequence update: January 23, 2007
Last modified: November 7, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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