Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 65 (05 Jun 2019)
Sequence version 1 (23 Jan 2007)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein
Submitted name:

Ankyrin repeat protein

Gene

ACLA_077490

Organism
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Ankyrin repeat proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:ACLA_077490Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri344612 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006701 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
FungiDB:ACLA_077490

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini503 – 601ANK_REP_REGIONInterPro annotationAdd BLAST99
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati536 – 568ANKPROSITE-ProRule annotationAdd BLAST33
Repeati569 – 601ANKPROSITE-ProRule annotationAdd BLAST33
Domaini1451 – 1491ANK_REP_REGIONInterPro annotationAdd BLAST41
Repeati1451 – 1483ANKPROSITE-ProRule annotationAdd BLAST33
Domaini1586 – 1628ANK_REP_REGIONInterPro annotationAdd BLAST43

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni591 – 643DisorderedSequence analysisAdd BLAST53
Regioni1156 – 1175DisorderedSequence analysisAdd BLAST20

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili72 – 92Sequence analysisAdd BLAST21
Coiled coili1000 – 1027Sequence analysisAdd BLAST28

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi591 – 639PolyampholyteSequence analysisAdd BLAST49

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

ANK repeatPROSITE-ProRule annotation, Coiled coilSequence analysis

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000199956

Identification of Orthologs from Complete Genome Data

More...
OMAi
GKKRADW

Database of Orthologous Groups

More...
OrthoDBi
31682at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00204 ANK, 5 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.20, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR018294 ISPD_synthase_CS

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12796 Ank_2, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01415 ANKYRIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00248 ANK, 12 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48403 SSF48403, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50297 ANK_REP_REGION, 3 hits
PS50088 ANK_REPEAT, 3 hits
PS01295 ISPD, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A1CLM3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAESYTLPAV PVKHSNFINH VKSHPQAPIQ DLVHPYNQYD AVLRKIYAQQ
60 70 80 90 100
PSHPAVAENL LNNVPLFDRN GEADLQIRAR DLTAESEELK AKFMMPLKNE
110 120 130 140 150
DRRPNGSPAV VSTLKEFQTN FNLFSESSLS DLDWSNVVAA GSAVTTSLVP
160 170 180 190 200
VPEEYRDSKR GLREFYHEKF APASDVDLFL YGLTEEQAIE KIKQIETRIK
210 220 230 240 250
DSILSETSTI RTKNAITIVS QYPTRHVQIV LRIYKSIAEI LTGFDVDCSC
260 270 280 290 300
AAYDGQQVYM APRAVGAFVT QINQVDLTRR SPSYENRLSK YARRGFEVFW
310 320 330 340 350
PMLDRSQIDP TIFERSFTRT VGLARLLVLE KLPKPSDRDA YIDKRRRERG
360 370 380 390 400
RPVPTRNWPA RQLRGNIKND WDDEVPDWDD EQDVSDYHTF TIPYGEKFHA
410 420 430 440 450
RKIERLLYTK DLLLNAEWNK PKDREVNLHR HPAFFGHFDD VVEDCCGFCP
460 470 480 490 500
VPVTPEEKEL AEEESKIYVS GRISFLRDNA GRQEIGSFNP ITETDWTEMA
510 520 530 540 550
YVGNTAGLCQ AIVDHDLEGV QEWLAQGHDV NRRDFTGRTA LHLAVMTSTP
560 570 580 590 600
EIVQCLVDQG ARLVARLADG RTALHLAAAR GSVDMIKTLL TKSEQNEEEE
610 620 630 640 650
EAKKEKARKE ASSNDSKDTS DNKDDGELIS HHPESEADDR SFATGSFVKV
660 670 680 690 700
KSDTKDAASE SVPDDTNEQE PDIYDINVIA WDNHASPLHL AIVNGHAAAV
710 720 730 740 750
EELVSSFGAD VLLPIKLLHG YNNTPRAAIL TLVLALQLPM EQAKAMTSKL
760 770 780 790 800
LQLGASPAQA DIEKKTSVTY IAGSPKYTEL LDLYLEHDHP AVERTINYIS
810 820 830 840 850
TGGWRWNPSA ETSLITAIKA GNVIGALKLL EANASPTIDF DEFIKVAQDN
860 870 880 890 900
LEGIRNNTSD QVKKNFNTHV AQPIIMAVMK DQPSIAQALL ARGADPNTMS
910 920 930 940 950
PDAYRVRDDD YARSNLKGES LLDCVRQKLK DLREYKPETS NLEPPKPLEQ
960 970 980 990 1000
DDEHYLSSFE QDTYQMWMAR GALDAARERY KADQKAYEER LQKDQAPCGV
1010 1020 1030 1040 1050
EEKKIAVKAL LEEFEILEAE LIAREAKTFG EMYPDIKMNT SDRHRSSSFS
1060 1070 1080 1090 1100
IKPPQFKVTV DFKRPDLNEA TREGYIQLFE AAWRGDLKTV KTLTMGMWGP
1110 1120 1130 1140 1150
ENKSPPLEIA TKDHRDFCPF HLAIIKGHLD VARAIIAIAE VQYKPEEKED
1160 1170 1180 1190 1200
NVRYRMRTES DEDNDSCCES SDIDEGDREE IGIEKHVLDD RFTIDNIGEV
1210 1220 1230 1240 1250
KTQVESKISP LSILQDNCYL SFFLPSPVPE DAKFHTLIQY AIWKDDVELL
1260 1270 1280 1290 1300
DFILDLGREL SMKGSNSSDQ SIFEAKEWDF TMAMQLGRLR CLKELIKRTG
1310 1320 1330 1340 1350
AGLPLDKLAE QSGAEVKEKP KFYQGLSIHG KKRADWAAAG RGITPTQPRE
1360 1370 1380 1390 1400
VHPPLLVAAR QGNVDAVEWF LGTAPGRYYA EFAEAFKHDK RLKRLAMGNK
1410 1420 1430 1440 1450
GIERSITSWL ECRRDLVLHC AVLSKPTDES EQLVRYLVKT VPHCMEVKSI
1460 1470 1480 1490 1500
EGYTPLALAF SLQRYAFAKI LIEAGADQTA RDKKGNNILH LTLNNATHPS
1510 1520 1530 1540 1550
DEKVKALPKI LGLIDNSLVP SLLQERSSQD PGALTPLAQW MVQGLTYPTY
1560 1570 1580 1590 1600
GAHIVQESGN QMKALKIILD FAQPTGQKHL EVLDGAGNTV IHDAVRCGVP
1610 1620 1630 1640 1650
QTLELLVKRR PDLLHRENAS GTTPAELAEA AWVAEVTSNP PNHERSNHNL
1660 1670 1680 1690 1700
FSSWSRDRYS ESLVRRKPDS FVMENDQAPT LKRKIYDFCC KSSEGVSAKR
1710 1720 1730 1740 1750
RLVTLFEANE VARRLASKHA EDTGRSRYRS RRRWMDPNEG DFADEVQAWH

KSAYQG
Length:1,756
Mass (Da):198,212
Last modified:January 23, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i36C65EAA7BB0D042
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
DS027057 Genomic DNA Translation: EAW09002.1

NCBI Reference Sequences

More...
RefSeqi
XP_001270428.1, XM_001270427.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
EAW09002; EAW09002; ACLA_077490

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
4702631

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
act:ACLA_077490

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS027057 Genomic DNA Translation: EAW09002.1
RefSeqiXP_001270428.1, XM_001270427.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiEAW09002; EAW09002; ACLA_077490
GeneIDi4702631
KEGGiact:ACLA_077490

Organism-specific databases

EuPathDBiFungiDB:ACLA_077490

Phylogenomic databases

HOGENOMiHOG000199956
OMAiGKKRADW
OrthoDBi31682at2759

Family and domain databases

CDDicd00204 ANK, 5 hits
Gene3Di1.25.40.20, 3 hits
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR018294 ISPD_synthase_CS
PfamiView protein in Pfam
PF12796 Ank_2, 1 hit
PRINTSiPR01415 ANKYRIN
SMARTiView protein in SMART
SM00248 ANK, 12 hits
SUPFAMiSSF48403 SSF48403, 3 hits
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 3 hits
PS50088 ANK_REPEAT, 3 hits
PS01295 ISPD, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA1CLM3_ASPCL
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A1CLM3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: January 23, 2007
Last sequence update: January 23, 2007
Last modified: June 5, 2019
This is version 65 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again