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Protein

Fructose-bisphosphate aldolase

Gene
N/A
Organism
Plasmodium falciparum
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.UniRule annotationSAAS annotation

Pathwayi: glycolysis

This protein is involved in step 4 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotationSAAS annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (GGI.R1), Glucose-6-phosphate isomerase (GPI)
  3. Probable ATP-dependent 6-phosphofructokinase (PFK9)
  4. Fructose-bisphosphate aldolase, Fructose-bisphosphate aldolase, Fructose-bisphosphate aldolase, Fructose-bisphosphate aldolase (P41), Fructose-bisphosphate aldolase, Fructose-bisphosphate aldolase, Fructose-bisphosphate aldolase (FBPA), Fructose-bisphosphate aldolase
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotation
Biological processGlycolysisUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayi
UPA00109;UER00183

Names & Taxonomyi

Protein namesi
Recommended name:
Fructose-bisphosphate aldolaseUniRule annotationSAAS annotation (EC:4.1.2.13UniRule annotationSAAS annotation)
OrganismiPlasmodium falciparumImported
Taxonomic identifieri5833 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)

Family & Domainsi

Sequence similaritiesi

Belongs to the class I fructose-bisphosphate aldolase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1557 Eukaryota
COG3588 LUCA

Family and domain databases

Gene3Di3.20.20.70, 1 hit
InterProiView protein in InterPro
IPR029768 Aldolase_I_AS
IPR013785 Aldolase_TIM
IPR000741 FBA_I
PfamiView protein in Pfam
PF00274 Glycolytic, 1 hit
PROSITEiView protein in PROSITE
PS00158 ALDOLASE_CLASS_I, 1 hit

Sequencei

Sequence statusi: Fragment.

A1BY85-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
PKKLPADVAE ELATTAQKLV QAGKGILAAD ESTQTIKKRF DNIKLENTIE
60 70 80 90 100
NRASYRDLLF GTKGLGKFIS GAILFEETLF QKNEAGVPMV NLLHNENIIP
110 120 130 140 150
GIKVDKGLVN IPCTDEEKST QGLDGLAERC KEYYKAGARF AKWRTVLVID
160 170 180 190 200
TAKGKPTDLS IHETAWGLAR YASICQQNRL VPIVEPEILA DGPHSIEVCA
210 220 230 240 250
VVTQKVLSCV FKALQENGVL LEGALLKPNM VTAGYECTAK TTTQDVGFLT
260 270 280 290 300
VRTLRRTVPP ALPGVVFLSG GQSEEEASVN LNSINALGPH PWALTFSYGR
310 320 330 340 350
ALQASVLNTW QGKKENVAKA REVLLQRAEA NSLATYGKYK GGAGGENAGA
Length:350
Mass (Da):37,778
Last modified:January 23, 2007 - v1
Checksum:i990561F753C94D6A
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei350Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ874471 Genomic DNA Translation: ABJ52701.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ874471 Genomic DNA Translation: ABJ52701.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG1557 Eukaryota
COG3588 LUCA

Enzyme and pathway databases

UniPathwayi
UPA00109;UER00183

Family and domain databases

Gene3Di3.20.20.70, 1 hit
InterProiView protein in InterPro
IPR029768 Aldolase_I_AS
IPR013785 Aldolase_TIM
IPR000741 FBA_I
PfamiView protein in Pfam
PF00274 Glycolytic, 1 hit
PROSITEiView protein in PROSITE
PS00158 ALDOLASE_CLASS_I, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA1BY85_PLAFA
AccessioniPrimary (citable) accession number: A1BY85
Entry historyiIntegrated into UniProtKB/TrEMBL: January 23, 2007
Last sequence update: January 23, 2007
Last modified: January 31, 2018
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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