UniProtKB - A1BB97 (A1BB97_PARDP)
Protein
Methylamine dehydrogenase (amicyanin)
Gene
Pden_4730
Organism
Paracoccus denitrificans (strain Pd 1222)
Status
Functioni
Methylamine dehydrogenase carries out the oxidation of methylamine. Electrons are passed from methylamine dehydrogenase to amicyanin.ARBA annotation
Catalytic activityi
- H2O + methylamine + 2 oxidized [amicyanin] = formaldehyde + 2 H+ + NH4+ + 2 reduced [amicyanin]ARBA annotationEC:1.4.9.1ARBA annotation
GO - Molecular functioni
- amine dehydrogenase activity Source: UniProtKB-EC
- methylamine dehydrogenase (amicyanin) activity Source: UniProtKB-EC
GO - Biological processi
- methylamine metabolic process Source: InterPro
Keywordsi
Molecular function | OxidoreductaseImportedARBA annotation |
Biological process | Electron transportARBA annotation, Transport |
Enzyme and pathway databases
BioCyci | PDEN318586:G1GW1-3081-MONOMER |
BRENDAi | 1.4.9.1, 3341 |
Names & Taxonomyi
Protein namesi | Recommended name: Methylamine dehydrogenase (amicyanin)ARBA annotation (EC:1.4.9.1ARBA annotation)Alternative name(s): Methylamine dehydrogenase heavy chainARBA annotation |
Gene namesi | Ordered Locus Names:Pden_4730Imported |
Encoded oni | Plasmid pPD1222Imported |
Organismi | Paracoccus denitrificans (strain Pd 1222)Imported |
Taxonomic identifieri | 318586 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Paracoccus › |
Proteomesi |
|
Subcellular locationi
- Periplasm ARBA annotation
GO - Cellular componenti
- periplasmic space Source: UniProtKB-SubCell
Keywords - Cellular componenti
PeriplasmARBA annotationPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 28 | Sequence analysisAdd BLAST | 28 | |
ChainiPRO_5002632245 | 29 – 417 | Methylamine dehydrogenase (amicyanin)Sequence analysisAdd BLAST | 389 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 212 ↔ 227 | UniRule annotationCombined sources |
Keywords - PTMi
Disulfide bondUniRule annotationProteomic databases
PRIDEi | A1BB97 |
Interactioni
Subunit structurei
Tetramer of two light and two heavy chains.
ARBA annotationProtein-protein interaction databases
IntActi | A1BB97, 2 interactors |
MINTi | A1BB97 |
STRINGi | 318586.Pden_4730 |
Structurei
3D structure databases
SMRi | A1BB97 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | A1BB97 |
Family & Domainsi
Sequence similaritiesi
Belongs to the aromatic amine dehydrogenase heavy chain family.ARBA annotation
Keywords - Domaini
SignalSequence analysisARBA annotationPhylogenomic databases
eggNOGi | COG3391, Bacteria |
HOGENOMi | CLU_059384_0_0_5 |
OMAi | DPGTQVW |
Family and domain databases
Gene3Di | 2.130.10.10, 1 hit |
InterProi | View protein in InterPro IPR013476, MeN_DH_Hvc IPR009451, Metamine_DH_Hvc IPR011044, Quino_amine_DH_bsu IPR015943, WD40/YVTN_repeat-like_dom_sf |
Pfami | View protein in Pfam PF06433, Me-amine-dh_H, 1 hit |
SUPFAMi | SSF50969, SSF50969, 1 hit |
TIGRFAMsi | TIGR02658, TTQ_MADH_Hv, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
A1BB97-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MALPPNFMPL FRASLIGLGL GCSALALAAS AQDAPEAETQ AQETQGQAAA
60 70 80 90 100
RAAAADLAAG QDDEPRILEA PAPDARRVYV NDPAHFAAVT QQFVIDGEAG
110 120 130 140 150
RVIGMIDGGF LPNPVVADDG SFIAHASTVF SRIARGERTD YVEVFDPVTL
160 170 180 190 200
LPTADIELPD APRFLVGTYP WMTSLTPDGK TLLFYQFSPA PAVGVVDLEG
210 220 230 240 250
KAFKRMLDVP DCYHIFPTAP DTFFMHCRDG SLAKVAFGTE GTPEITHTEV
260 270 280 290 300
FHPEDEFLIN HPAYSQKAGR LVWPTYTGKI HQIDLSSGDA KFLPAVEALT
310 320 330 340 350
EAERADGWRP GGWQQVAYHR ALDRIYLLVD QRDEWRHKTA SRFVVVLDAK
360 370 380 390 400
TGERLAKFEM GHEIDSINVS QDEKPLLYAL STGDKTLYIH DAESGEELRS
410
VNQLGHGPQV ITTADMG
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP000491 Genomic DNA Translation: ABL72791.1 |
RefSeqi | WP_011750950.1, NC_008688.1 |
Genome annotation databases
EnsemblBacteriai | ABL72791; ABL72791; Pden_4730 |
KEGGi | pde:Pden_4730 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP000491 Genomic DNA Translation: ABL72791.1 |
RefSeqi | WP_011750950.1, NC_008688.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
3L4M | X-ray | 2.02 | D/F | 32-417 | [»] | |
3L4O | X-ray | 2.05 | D/F | 32-417 | [»] | |
3ORV | X-ray | 1.91 | D/F | 32-417 | [»] | |
3PXS | X-ray | 2.22 | D/F | 32-417 | [»] | |
3PXT | X-ray | 2.16 | D/F | 32-417 | [»] | |
3PXW | X-ray | 2.11 | D/F | 33-417 | [»] | |
3RLM | X-ray | 2.13 | D/F | 32-417 | [»] | |
3RMZ | X-ray | 1.72 | D/F | 32-417 | [»] | |
3RN0 | X-ray | 1.91 | D/F | 32-417 | [»] | |
3RN1 | X-ray | 1.93 | D/F | 32-417 | [»] | |
3SJL | X-ray | 1.63 | D/F | 32-417 | [»] | |
3SLE | X-ray | 2.52 | D/F | 33-417 | [»] | |
3SVW | X-ray | 1.86 | D/F | 32-417 | [»] | |
3SWS | X-ray | 1.86 | D/F | 32-417 | [»] | |
3SXT | X-ray | 1.81 | D/F | 32-417 | [»] | |
4FA1 | X-ray | 2.18 | D/F | 33-417 | [»] | |
4FA4 | X-ray | 2.14 | D/F | 33-417 | [»] | |
4FA5 | X-ray | 1.94 | D/F | 33-417 | [»] | |
4FA9 | X-ray | 2.09 | D/F | 33-417 | [»] | |
4FAN | X-ray | 2.08 | D/F | 33-417 | [»] | |
4FAV | X-ray | 2.08 | D/F | 33-417 | [»] | |
4FB1 | X-ray | 2.15 | D/F | 33-417 | [»] | |
4K3I | X-ray | 2.00 | D/F | 33-417 | [»] | |
4L1Q | X-ray | 1.92 | D/F | 33-417 | [»] | |
4L3G | X-ray | 2.05 | D/F | 33-417 | [»] | |
4L3H | X-ray | 1.79 | D/F | 33-417 | [»] | |
4O1Q | X-ray | 2.59 | D/F | 33-417 | [»] | |
4Y5R | X-ray | 2.80 | D/F | 42-417 | [»] | |
SMRi | A1BB97 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
IntActi | A1BB97, 2 interactors |
MINTi | A1BB97 |
STRINGi | 318586.Pden_4730 |
Proteomic databases
PRIDEi | A1BB97 |
Genome annotation databases
EnsemblBacteriai | ABL72791; ABL72791; Pden_4730 |
KEGGi | pde:Pden_4730 |
Phylogenomic databases
eggNOGi | COG3391, Bacteria |
HOGENOMi | CLU_059384_0_0_5 |
OMAi | DPGTQVW |
Enzyme and pathway databases
BioCyci | PDEN318586:G1GW1-3081-MONOMER |
BRENDAi | 1.4.9.1, 3341 |
Miscellaneous databases
EvolutionaryTracei | A1BB97 |
Family and domain databases
Gene3Di | 2.130.10.10, 1 hit |
InterProi | View protein in InterPro IPR013476, MeN_DH_Hvc IPR009451, Metamine_DH_Hvc IPR011044, Quino_amine_DH_bsu IPR015943, WD40/YVTN_repeat-like_dom_sf |
Pfami | View protein in Pfam PF06433, Me-amine-dh_H, 1 hit |
SUPFAMi | SSF50969, SSF50969, 1 hit |
TIGRFAMsi | TIGR02658, TTQ_MADH_Hv, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A1BB97_PARDP | |
Accessioni | A1BB97Primary (citable) accession number: A1BB97 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | January 23, 2007 |
Last sequence update: | January 23, 2007 | |
Last modified: | December 2, 2020 | |
This is version 99 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |