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UniProtKB - A1A8H2 (ALLR_ECOK1)
Protein
HTH-type transcriptional repressor AllR
Gene
allR
Organism
Escherichia coli O1:K1 / APEC
Status
Functioni
Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS-allA intergenic region (By similarity).
By similaritySites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 207 | GlyoxylateBy similarity | 1 | |
Binding sitei | 217 | GlyoxylateBy similarity | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 43 – 62 | H-T-H motifPROSITE-ProRule annotationAdd BLAST | 20 |
GO - Molecular functioni
- DNA binding Source: UniProtKB-KW
GO - Biological processi
- regulation of transcription, DNA-templated Source: InterPro
Keywordsi
Molecular function | DNA-binding, Repressor |
Biological process | Transcription, Transcription regulation |
Names & Taxonomyi
Protein namesi | Recommended name: HTH-type transcriptional repressor AllRAlternative name(s): Negative regulator of allantoin and glyoxylate utilization operons |
Gene namesi | Name:allR Ordered Locus Names:Ecok1_04680 ORF Names:APECO1_1508 |
Organismi | Escherichia coli O1:K1 / APEC |
Taxonomic identifieri | 405955 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000313699 | 1 – 271 | HTH-type transcriptional repressor AllRAdd BLAST | 271 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 21 – 83 | HTH iclR-typePROSITE-ProRule annotationAdd BLAST | 63 | |
Domaini | 98 – 267 | IclR-EDPROSITE-ProRule annotationAdd BLAST | 170 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 154 – 156 | Glyoxylate bindingBy similarity | 3 | |
Regioni | 234 – 236 | Glyoxylate bindingBy similarity | 3 |
Phylogenomic databases
HOGENOMi | CLU_062618_7_1_6 |
OMAi | PKSSLYM |
Family and domain databases
Gene3Di | 1.10.10.10, 1 hit 3.30.450.40, 1 hit |
InterProi | View protein in InterPro IPR029016, GAF-like_dom_sf IPR014757, Tscrpt_reg_IclR_C IPR005471, Tscrpt_reg_IclR_N IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
Pfami | View protein in Pfam PF09339, HTH_IclR, 1 hit PF01614, IclR, 1 hit |
SMARTi | View protein in SMART SM00346, HTH_ICLR, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit |
PROSITEi | View protein in PROSITE PS51077, HTH_ICLR, 1 hit PS51078, ICLR_ED, 1 hit |
i Sequence
Sequence statusi: Complete.
A1A8H2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTEVRRRGRP GQAEPVAQKG AQALERGIAI LQYLEKSGGS SSVSDISLNL
60 70 80 90 100
DLPLSTTFRL LKVLQAADFV YQDSQLGWWH IGLGVFNVGA AYIHNRDVLS
110 120 130 140 150
VAGPFMRRLM LLSGETVNVA IRNGNEAVLI GQLECKSMVR MCAPLGSRLP
160 170 180 190 200
LHASGAGKAL LYPLAEEELM SIILQTGLQQ FTPTTLVDMP TLLKDLEQAR
210 220 230 240 250
ELGYTVDKEE HVVGLNCIAS AIYDDVGSVV AAISISGPSS RLTEDRFVSQ
260 270
GELVRDTARD ISTALGLKAH L
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP000468 Genomic DNA Translation: ABI99961.1 |
RefSeqi | WP_000141274.1, NC_008563.1 |
Genome annotation databases
EnsemblBacteriai | ABI99961; ABI99961; APECO1_1508 |
KEGGi | ecv:APECO1_1508 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP000468 Genomic DNA Translation: ABI99961.1 |
RefSeqi | WP_000141274.1, NC_008563.1 |
3D structure databases
SMRi | A1A8H2 |
ModBasei | Search... |
Genome annotation databases
EnsemblBacteriai | ABI99961; ABI99961; APECO1_1508 |
KEGGi | ecv:APECO1_1508 |
Phylogenomic databases
HOGENOMi | CLU_062618_7_1_6 |
OMAi | PKSSLYM |
Family and domain databases
Gene3Di | 1.10.10.10, 1 hit 3.30.450.40, 1 hit |
InterProi | View protein in InterPro IPR029016, GAF-like_dom_sf IPR014757, Tscrpt_reg_IclR_C IPR005471, Tscrpt_reg_IclR_N IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
Pfami | View protein in Pfam PF09339, HTH_IclR, 1 hit PF01614, IclR, 1 hit |
SMARTi | View protein in SMART SM00346, HTH_ICLR, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit |
PROSITEi | View protein in PROSITE PS51077, HTH_ICLR, 1 hit PS51078, ICLR_ED, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | ALLR_ECOK1 | |
Accessioni | A1A8H2Primary (citable) accession number: A1A8H2 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 15, 2008 |
Last sequence update: | January 23, 2007 | |
Last modified: | September 29, 2021 | |
This is version 84 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |