Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 68 (23 Feb 2022)
Sequence version 1 (23 Jan 2007)
Previous versions | rss
Add a publicationFeedback
Protein

SANT and BTB domain regulator of class switch recombination

Gene

Sanbr

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
SANT and BTB domain regulator of class switch recombinationBy similarity
Short name:
SANT and BTB domain regulator of CSR
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SanbrBy similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 14

Organism-specific databases

Rat genome database

More...
RGDi
1305110, RGD1305110

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003246001 – 737SANT and BTB domain regulator of class switch recombinationAdd BLAST737

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
A1A5R8

PRoteomics IDEntifications database

More...
PRIDEi
A1A5R8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSRNOG00000054669, Expressed in cerebellum and 20 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A1A5R8, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
A1A5R8, RN

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10116.ENSRNOP00000007385

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A1A5R8

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini21 – 59SANTPROSITE-ProRule annotationAdd BLAST39
Domaini147 – 255BTBPROSITE-ProRule annotationAdd BLAST109

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni555 – 618DisorderedSequence analysisAdd BLAST64

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the KIAA1841 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QRE4, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000008178

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
A1A5R8

Identification of Orthologs from Complete Genome Data

More...
OMAi
INWESVA

Database of Orthologous Groups

More...
OrthoDBi
904755at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
A1A5R8

TreeFam database of animal gene trees

More...
TreeFami
TF324503

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00167, SANT, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.710.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR045902, SANBR-like
IPR021777, SANBR_BTB
IPR001005, SANT/Myb
IPR011333, SKP1/BTB/POZ_sf

The PANTHER Classification System

More...
PANTHERi
PTHR20946, PTHR20946, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF11822, DUF3342, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

A1A5R8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSRGCPENNN FLTNNNQMVL DMILYPLIGI PQTINWETVA RLVPGLTPKE
60 70 80 90 100
CVKRFDELKS CGSSPVDNQY NPLMAAGEGP VETLATYIKS SLLDAQGDFQ
110 120 130 140 150
ETPVDQDTVS KAGRHSIATT RNCSSESENC TARNAGEETG DSEGPNMVIH
160 170 180 190 200
VCDEAKSLKE DFICPRDLLI SEMKYFAEYL SVDAQRWEEV DISVHCDVHI
210 220 230 240 250
FNWLIKYVKR NTKDSKDCEL PALEPGNVIS ILISSEFLKM DSLVEQCIQY
260 270 280 290 300
CHKNMNAIVA APCNMNCINV NLLTRIADLF THNEIDDLKD KKDKFRSKLF
310 320 330 340 350
CKKIERLFDP EYFNPDSRNN AATLYRCCLC KKLLTRETER RISCIPGKIN
360 370 380 390 400
VDRHGNIIYI HIRDKTWDVH EYLNSLFEEL KSWRDVYWRL WGTINWLTCS
410 420 430 440 450
RCYQAFLCIE FSHCQYHSEV VVYSSAVNSL NTVGTGIYPC CNQKVLRFDP
460 470 480 490 500
TQLTKGCKVR DHMVLLHDQG ENDDSLSCPT AKILDDLHKH KDVIAVPFLK
510 520 530 540 550
DPVSDPGVGS CDEKGLEYEI LLEPNTPWGS KTGELNAFLS LKNWTLQLKQ
560 570 580 590 600
QSLFSEEEEY TTGSEVTEDE VGDEEEISKK QRKKEKPKKF TKPPKKQLSS
610 620 630 640 650
PCSQKKEKTL EKSTSRDVSP FVVSMQKNKW DATRSLRFNQ DAQREDDQRR
660 670 680 690 700
MSEITGHLIK MRLGDLDRVK AKESKEFAGG IYSRLEAQVK ASVPVTARQN
710 720 730
SSDKNQSNIP QRHLFNYVHS NFIRNSQKLE TSQMFIN
Length:737
Mass (Da):84,345
Last modified:January 23, 2007 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iECE522D63DAF1CE6
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0G2K9M0A0A0G2K9M0_RAT
Similar to KIAA1841 protein
RGD1305110 RGD1305110_predicted, rCG_23247
718Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0G2K7U6A0A0G2K7U6_RAT
Similar to KIAA1841 protein
RGD1305110
708Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BC128776 mRNA Translation: AAI28777.1

NCBI Reference Sequences

More...
RefSeqi
NP_001094441.1, NM_001100971.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSRNOT00000088116; ENSRNOP00000071734; ENSRNOG00000054669

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
305579

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
rno:305579

UCSC genome browser

More...
UCSCi
RGD:1305110, rat

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC128776 mRNA Translation: AAI28777.1
RefSeqiNP_001094441.1, NM_001100971.1

3D structure databases

SMRiA1A5R8
ModBaseiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000007385

Proteomic databases

PaxDbiA1A5R8
PRIDEiA1A5R8

Genome annotation databases

EnsembliENSRNOT00000088116; ENSRNOP00000071734; ENSRNOG00000054669
GeneIDi305579
KEGGirno:305579
UCSCiRGD:1305110, rat

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
84542
RGDi1305110, RGD1305110

Phylogenomic databases

eggNOGiENOG502QRE4, Eukaryota
GeneTreeiENSGT00390000008178
InParanoidiA1A5R8
OMAiINWESVA
OrthoDBi904755at2759
PhylomeDBiA1A5R8
TreeFamiTF324503

Miscellaneous databases

Protein Ontology

More...
PROi
PR:A1A5R8

Gene expression databases

BgeeiENSRNOG00000054669, Expressed in cerebellum and 20 other tissues
ExpressionAtlasiA1A5R8, baseline and differential
GenevisibleiA1A5R8, RN

Family and domain databases

CDDicd00167, SANT, 1 hit
Gene3Di3.30.710.10, 1 hit
InterProiView protein in InterPro
IPR045902, SANBR-like
IPR021777, SANBR_BTB
IPR001005, SANT/Myb
IPR011333, SKP1/BTB/POZ_sf
PANTHERiPTHR20946, PTHR20946, 1 hit
PfamiView protein in Pfam
PF11822, DUF3342, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiK1841_RAT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A1A5R8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: January 23, 2007
Last modified: February 23, 2022
This is version 68 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again