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Protein
Submitted name:

Keratin 13, isoform CRA_a

Gene

KRT13

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Keratin 13, isoform CRA_aImported
Gene namesi
Name:KRT13Imported
ORF Names:hCG_1730613Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Intermediate filamentPROSITE-ProRule annotationSAAS annotation, KeratinImported

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA30202

PTM / Processingi

Proteomic databases

PRIDEiA1A4E9

Interactioni

Protein-protein interaction databases

IntActiA1A4E9, 44 interactors

Structurei

3D structure databases

SMRiA1A4E9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini104 – 416IF rodInterPro annotationAdd BLAST313

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili108 – 142Sequence analysisAdd BLAST35
Coiled coili208 – 253Sequence analysisAdd BLAST46
Coiled coili274 – 294Sequence analysisAdd BLAST21
Coiled coili314 – 348Sequence analysisAdd BLAST35
Coiled coili360 – 401Sequence analysisAdd BLAST42

Sequence similaritiesi

Belongs to the intermediate filament family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domaini

Coiled coilPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410IFTF Eukaryota
ENOG410Y9IV LUCA
HOVERGENiHBG013015
KOiK07604

Family and domain databases

InterProiView protein in InterPro
IPR001664 IF
IPR018039 IF_conserved
IPR039008 IF_rod_dom
IPR002957 Keratin_I
PANTHERiPTHR23239 PTHR23239, 1 hit
PfamiView protein in Pfam
PF00038 Filament, 1 hit
PRINTSiPR01248 TYPE1KERATIN
SMARTiView protein in SMART
SM01391 Filament, 1 hit
PROSITEiView protein in PROSITE
PS00226 IF_ROD_1, 1 hit
PS51842 IF_ROD_2, 1 hit

Sequencei

Sequence statusi: Complete.

A1A4E9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLRLQSSSA SYGGGFGGGS CQLGGGRGVS TCSTRFVSGG SAGGYGGGVS
60 70 80 90 100
CGFGGGAGSG FGGGYGGGLG GGYGGGLGGG FGGGFAGGFV DFGACDGGLL
110 120 130 140 150
TGNEKITMQN LNDRLASYLE KVRALEEANA DLEVKIRDWH LKQSPASPER
160 170 180 190 200
DYSPYYKTIE ELRDKILTAT IENNRVILEI DNARLAVDDF RLKYENELAL
210 220 230 240 250
RQSVEADING LRRVLDELTL SKTDLEMQIE SLNEELAYMK KNHEEEMKEF
260 270 280 290 300
SNQVVGQVNV EMDATPGIDL TRVLAEMREQ YEAMAERNRR DAEEWFHAKS
310 320 330 340 350
AELNKEVSTN TAMIQTSKTE ITELRRTLQG LEIELQSQLS MKAGLENTVA
360 370 380 390 400
ETECRYALQL QQIQGLISSI EAQLSELRSE MECQNQEYKM LLDIKTRLEQ
410 420 430 440 450
EIATYRSLLE GQDAKMIGFP SSAGSVSPRS TSVTTTSSAS VTTTSNASGR

RTSDVRRP
Length:458
Mass (Da):49,586
Last modified:January 23, 2007 - v1
Checksum:i9E033A247CD2B106
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC126184 mRNA Translation: AAI26185.1
BC136494 mRNA Translation: AAI36495.1
CH471152 Genomic DNA Translation: EAW60740.1
RefSeqiNP_705694.2, NM_153490.2
UniGeneiHs.654550

Genome annotation databases

GeneIDi3860
KEGGihsa:3860

Similar proteinsi

Entry informationi

Entry nameiA1A4E9_HUMAN
AccessioniPrimary (citable) accession number: A1A4E9
Entry historyiIntegrated into UniProtKB/TrEMBL: January 23, 2007
Last sequence update: January 23, 2007
Last modified: June 20, 2018
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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