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Protein
Submitted name:

LIM domain only 7

Gene

Lmo7

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
LIM domain only 7Imported
Gene namesi
Name:Lmo7Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1353586 Lmo7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PeptideAtlasiA0T1J8
PRIDEiA0T1J8

PTM databases

iPTMnetiA0T1J8
PhosphoSitePlusiA0T1J8

Expressioni

Gene expression databases

GenevisibleiA0T1J8 MM

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

IntActiA0T1J8, 2 interactors

Structurei

3D structure databases

ProteinModelPortaliA0T1J8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 129Calponin-homology (CH)InterPro annotationAdd BLAST118
Domaini1036 – 1091PDZInterPro annotationAdd BLAST56
Domaini1628 – 1694LIM zinc-bindingInterPro annotationAdd BLAST67

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili669 – 724Sequence analysisAdd BLAST56
Coiled coili1221 – 1271Sequence analysisAdd BLAST51
Coiled coili1325 – 1366Sequence analysisAdd BLAST42
Coiled coili1374 – 1410Sequence analysisAdd BLAST37

Keywords - Domaini

Coiled coilSequence analysis, LIM domainPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1704 Eukaryota
ENOG410ZBDQ LUCA
HOGENOMiHOG000043081
HOVERGENiHBG049143

Family and domain databases

CDDicd00014 CH, 1 hit
Gene3Di1.10.418.10, 1 hit
InterProiView protein in InterPro
IPR001715 CH-domain
IPR036872 CH_dom_sf
IPR031865 DUF4757
IPR029978 LMO-7
IPR001478 PDZ
IPR036034 PDZ_sf
IPR003096 SM22_calponin
IPR001781 Znf_LIM
PANTHERiPTHR15551:SF4 PTHR15551:SF4, 1 hit
PfamiView protein in Pfam
PF00307 CH, 1 hit
PF15949 DUF4757, 2 hits
PF00412 LIM, 1 hit
PF00595 PDZ, 1 hit
PRINTSiPR00888 SM22CALPONIN
SMARTiView protein in SMART
SM00033 CH, 1 hit
SM00132 LIM, 1 hit
SM00228 PDZ, 1 hit
SUPFAMiSSF47576 SSF47576, 1 hit
SSF50156 SSF50156, 1 hit
PROSITEiView protein in PROSITE
PS50021 CH, 1 hit
PS00478 LIM_DOMAIN_1, 1 hit
PS50023 LIM_DOMAIN_2, 1 hit
PS50106 PDZ, 1 hit

Sequencei

Sequence statusi: Complete.

A0T1J8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEGMEDAEAD CSVAFAEAQR WVEAVTEKNF ETTDFRASLE NGVLLCDLIN
60 70 80 90 100
KLKPGVVKKI NRLSTPIAGL DNINVFLRAC EQIGLKEAQL FHPGDLQDLS
110 120 130 140 150
NRVTVKQEET DRRLKNVLIT LYWLGRKAQS NPYYNGPYLN LKAFETLLGQ
160 170 180 190 200
ALTKALEDSS CLKRSGRDSG YGDIWCPDRG EFPAPPGSHR REDSFESLDS
210 220 230 240 250
LGSRSLTSCS SDFTLRVGKE GCESDIDWEF TFKMQDYNKD DMSYRRISAI
260 270 280 290 300
EPKSALPFNR FLPNKSKQPS YVPAPFEKKR PDKHEDNRRS WASPVYTETD
310 320 330 340 350
GTFSSTQRRT WGPKMETWHT VQETSTSSWC VEEEEEKLTR MPNIVKDDLY
360 370 380 390 400
VRKLSPVMPS PGSSFDQFLP KCWTPEDMNW KKIKRETYKP WYKEFQGFSQ
410 420 430 440 450
FLLLQALQTY SDDILSSETS VKLDPTSGPR LITRRKNRSP APGYRAHDLE
460 470 480 490 500
LPALDPDLEN DDFFVRKTGA FHANPCVLRA FEDFRSFSEP DDAVERDIIL
510 520 530 540 550
QCREGELVLP DLEKDDMIVR RIPAQKKEVP LSGAPDRYQP VPFPEPWTLP
560 570 580 590 600
PEIQAKFLSV LERTRPPKEQ SSGCRVLVPS YRQKKDDMLA RKIQSWKLGT
610 620 630 640 650
AVPPISFKPG PCSEADLQKW EAIWEASRLR HRKRLMVERL FQKIYGENGS
660 670 680 690 700
KSMSDVSAED VQNLRQVRYE EMQKIKSQLK EQDQKWQDDL AKWKNRRKSY
710 720 730 740 750
TSDLQKKKEE REEIEKQALE KSDRSSKTFR EMLQDRESRG STVTSWRRTY
760 770 780 790 800
SSDDILDDGV LPPTVTLSET SYQSERLEDE ARAHPAEMPK EDSTTFANRE
810 820 830 840 850
DSVVAETQLA SHSPEEQRLA PSPSEEPRQA SGSSAEPHQA PLLSTEPRRT
860 870 880 890 900
PLPSEEPHQA SLSSTLQRPS SLSSQQSWST RAESTRISAS LPRSYQRTDT
910 920 930 940 950
ARLTSVVTAR PFGTSSRGIS SLPRSYTMDD GWKYNGDVEV VKREQLDLGR
960 970 980 990 1000
ATGPKPDSSH FISGSASEKE VIATEDVASL SSPTLPSSSL SHDRAVSSKA
1010 1020 1030 1040 1050
TFSSMSGLDS VSDSGEGRGS PLREVSRSLD QFSDMRVSIN QTPGNKPVFG
1060 1070 1080 1090 1100
FTIKWDISGI FVASVEQGSP AEFSQLQVDD EILAINNTKF SYKDTKKWEE
1110 1120 1130 1140 1150
VMANAQETGN LVMDVRRYGK SGSSETKWID TTSGIYNSDK SSSLSVTTDF
1160 1170 1180 1190 1200
SESLQSPYTE SKEVNGIHEE SNPFDSKASE SISLKNLKRR SQFFEQGSSD
1210 1220 1230 1240 1250
SVAPDLPVPT LSAPSRWAWD QEEERRRQER WQKEQDRLLQ EKYQREQEKL
1260 1270 1280 1290 1300
REEWQRAQQE AERENSKYLD EELMVLNSNS ISLTSREPVA ATWEATWSEG
1310 1320 1330 1340 1350
SKSLDSEGTR AGEEDRGQLE DDAVYEDQSQ KLQELEQEKK RKEQEAQEEE
1360 1370 1380 1390 1400
RRKQREAQAW AEAEAKAWAE AQARAEAEAK ARAEAQARAE AEAQKRAEAQ
1410 1420 1430 1440 1450
KLQAERERET SVKIYQYRRP IDSYDLPKRE DDTSGMLPTD RSKSRSTTEL
1460 1470 1480 1490 1500
NDPLIEKNGS SKYSERIGAT SFSHRSSKKD QAPSEAELER QQILQEMRKR
1510 1520 1530 1540 1550
TSLHNDNSWI RQRSASVNKE PICLPGIMRR GESLDNLDSQ RPGSWRQSPW
1560 1570 1580 1590 1600
HSQPAGVYAS SSVQDFSRPP PQLLSTSNRA YMRNPSSAVP PPAGSVKTSP
1610 1620 1630 1640 1650
GSPSPRSHSP SMSQSGSQLR NRSVSGKRVC SYCNNILGKG AAMIIETLGL
1660 1670 1680 1690
SYHLHCFKCV SCGCDLGGSS SGAEVRIRNH QLYCNDCYLR FKSGRPTAM
Length:1,699
Mass (Da):192,560
Last modified:January 9, 2007 - v1
Checksum:iB35C5A303632E7AD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF071857 mRNA Translation: ABK60217.1
RefSeqiNP_963287.2, NM_201529.2
UniGeneiMm.218981

Genome annotation databases

GeneIDi380928

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF071857 mRNA Translation: ABK60217.1
RefSeqiNP_963287.2, NM_201529.2
UniGeneiMm.218981

3D structure databases

ProteinModelPortaliA0T1J8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiA0T1J8, 2 interactors

PTM databases

iPTMnetiA0T1J8
PhosphoSitePlusiA0T1J8

Proteomic databases

PeptideAtlasiA0T1J8
PRIDEiA0T1J8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi380928

Organism-specific databases

CTDi4008
MGIiMGI:1353586 Lmo7

Phylogenomic databases

eggNOGiKOG1704 Eukaryota
ENOG410ZBDQ LUCA
HOGENOMiHOG000043081
HOVERGENiHBG049143

Miscellaneous databases

ChiTaRSiLmo7 mouse
SOURCEiSearch...

Gene expression databases

GenevisibleiA0T1J8 MM

Family and domain databases

CDDicd00014 CH, 1 hit
Gene3Di1.10.418.10, 1 hit
InterProiView protein in InterPro
IPR001715 CH-domain
IPR036872 CH_dom_sf
IPR031865 DUF4757
IPR029978 LMO-7
IPR001478 PDZ
IPR036034 PDZ_sf
IPR003096 SM22_calponin
IPR001781 Znf_LIM
PANTHERiPTHR15551:SF4 PTHR15551:SF4, 1 hit
PfamiView protein in Pfam
PF00307 CH, 1 hit
PF15949 DUF4757, 2 hits
PF00412 LIM, 1 hit
PF00595 PDZ, 1 hit
PRINTSiPR00888 SM22CALPONIN
SMARTiView protein in SMART
SM00033 CH, 1 hit
SM00132 LIM, 1 hit
SM00228 PDZ, 1 hit
SUPFAMiSSF47576 SSF47576, 1 hit
SSF50156 SSF50156, 1 hit
PROSITEiView protein in PROSITE
PS50021 CH, 1 hit
PS00478 LIM_DOMAIN_1, 1 hit
PS50023 LIM_DOMAIN_2, 1 hit
PS50106 PDZ, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0T1J8_MOUSE
AccessioniPrimary (citable) accession number: A0T1J8
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2007
Last sequence update: January 9, 2007
Last modified: September 12, 2018
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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