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Protein
Submitted name:

Zinc finger FYVE domain-containing protein 9 splice variant Z2.1

Gene

Zfyve9

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-2173789 TGF-beta receptor signaling activates SMADs

Names & Taxonomyi

Protein namesi
Submitted name:
Zinc finger FYVE domain-containing protein 9 splice variant Z2.1Imported
Submitted name:
Zinc finger, FYVE domain-containing 9Imported
Gene namesi
Name:Zfyve9Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:2652838 Zfyve9

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000034557 Expressed in 223 organ(s), highest expression level in ear

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000039852

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini54 – 92SARAInterPro annotationAdd BLAST39
Domaini329 – 681DUF3480InterPro annotationAdd BLAST353

Phylogenomic databases

eggNOGiKOG1841 Eukaryota
ENOG410XSEQ LUCA
GeneTreeiENSGT00840000129741
HOGENOMiHOG000111121
HOVERGENiHBG079622
TreeFamiTF324904

Family and domain databases

Gene3Di4.10.720.10, 1 hit
InterProiView protein in InterPro
IPR022557 DUF3480
IPR024608 SARA_Smad-bd
IPR037145 SARA_Smad-bd_sf
IPR011011 Znf_FYVE_PHD
PfamiView protein in Pfam
PF11979 DUF3480, 1 hit
PF11409 SARA, 1 hit
SUPFAMiSSF57903 SSF57903, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

A0S860-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNLNKMKVFC ASCCSLKCKL LYMDRKEARV CVICHSVLMN AQAWENMMSA
60 70 80 90 100
SSQSPNPNNP AEYCSTIPPL QQAQASGALS SPPPTVMVPV GVLKHPGTEV
110 120 130 140 150
PQPREQRRVW FADGILPNGE VADAAKLTMN GTSSAGTLAV SHDPVKPVAT
160 170 180 190 200
SPLPTEADTS LFSGSITQVG SPVGSAMNLI PEDGLPPILI STGVKGDYAV
210 220 230 240 250
EEKPSQISVM QQLEDGGPDP LVFVLNANLL SMVKIVNYVN RKCWCFTTKG
260 270 280 290 300
MHAVGQSEIV ILLQCLPDEK CLPKDIFNHF VQLYRDALAG NVVGSLGHSF
310 320 330 340 350
FSQSFLGSKE HGGFLYVTST YQSLQDLVLP TPPYLFGILI QKWETPWAKV
360 370 380 390 400
FPIRLLLRLG AEYRLYPCPL FSVRFRKPLF GETGHTIMNL LADFRNYQYT
410 420 430 440 450
LPVVQGLVVD MEVRKTSIKI PSNRYNEMMK AMNKSNEHVL AGGACFNEKA
460 470 480 490 500
DSHLVCVQND DGNYQTQAIS IHNQPRKVTG ASFFVFSGAL KSSSGYLAKS
510 520 530 540 550
SIVEDGVMVQ ITAENMDSLR QALREMKDFT ITCGKADAED PQEQIHIQWV
560 570 580 590 600
DDDKTVNKGV VSPIDGKSME SITNVKIFHG SEYKANGKVI RWTEVFFLEN
610 620 630 640 650
DDHHNCLSDP ADHSRLTEHV AKAFCLALCP HLKLLKEDGM TKLGLRVTLD
660 670 680 690 700
SDQVGYQAGS NGQPLPSQYM NDLDSALVPV IHGGACQLSE GPVVMELIFY

ILENIA
Length:706
Mass (Da):77,539
Last modified:January 9, 2007 - v1
Checksum:i7E7E8F1E06FF307D
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A8Y5G5A8Y5G5_MOUSE
Zinc finger FYVE domain-containing ...
Zfyve9
1,338Annotation score:
A2A8R0A2A8R0_MOUSE
Zinc finger FYVE domain-containing ...
Zfyve9 mCG_17975
1,397Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL607070 Genomic DNA No translation available.
AL626783 Genomic DNA No translation available.
AL671909 Genomic DNA No translation available.
DQ303413 mRNA Translation: ABC18000.1
RefSeqiNP_899123.2, NM_183300.2
UniGeneiMm.196776

Genome annotation databases

EnsembliENSMUST00000042185; ENSMUSP00000039852; ENSMUSG00000034557
GeneIDi230597
UCSCiuc008ubn.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL607070 Genomic DNA No translation available.
AL626783 Genomic DNA No translation available.
AL671909 Genomic DNA No translation available.
DQ303413 mRNA Translation: ABC18000.1
RefSeqiNP_899123.2, NM_183300.2
UniGeneiMm.196776

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000039852

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000042185; ENSMUSP00000039852; ENSMUSG00000034557
GeneIDi230597
UCSCiuc008ubn.1 mouse

Organism-specific databases

CTDi9372
MGIiMGI:2652838 Zfyve9

Phylogenomic databases

eggNOGiKOG1841 Eukaryota
ENOG410XSEQ LUCA
GeneTreeiENSGT00840000129741
HOGENOMiHOG000111121
HOVERGENiHBG079622
TreeFamiTF324904

Enzyme and pathway databases

ReactomeiR-MMU-2173789 TGF-beta receptor signaling activates SMADs

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000034557 Expressed in 223 organ(s), highest expression level in ear

Family and domain databases

Gene3Di4.10.720.10, 1 hit
InterProiView protein in InterPro
IPR022557 DUF3480
IPR024608 SARA_Smad-bd
IPR037145 SARA_Smad-bd_sf
IPR011011 Znf_FYVE_PHD
PfamiView protein in Pfam
PF11979 DUF3480, 1 hit
PF11409 SARA, 1 hit
SUPFAMiSSF57903 SSF57903, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0S860_MOUSE
AccessioniPrimary (citable) accession number: A0S860
Entry historyiIntegrated into UniProtKB/TrEMBL: January 9, 2007
Last sequence update: January 9, 2007
Last modified: November 7, 2018
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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