UniProtKB - A0QV25 (A0QV25_MYCS2)
Protein
Chromosome partition protein Smc
Gene
smc
Organism
Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
Status
Functioni
Required for chromosome condensation and partitioning.UniRule annotation
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 32 – 39 | ATPUniRule annotation | 8 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-UniRule
- DNA binding Source: UniProtKB-UniRule
GO - Biological processi
- chromosome condensation Source: InterPro
- DNA replication Source: UniProtKB-UniRule
- sister chromatid cohesion Source: InterPro
Keywordsi
Molecular function | DNA-bindingUniRule annotation |
Ligand | ATP-bindingUniRule annotationARBA annotation, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Chromosome partition protein SmcUniRule annotation |
Gene namesi | Name:smcUniRule annotationImported Ordered Locus Names:MSMEG_2423Imported |
Organismi | Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)Imported |
Taxonomic identifieri | 246196 [NCBI] |
Taxonomic lineagei | Bacteria › Actinobacteria › Corynebacteriales › Mycobacteriaceae › Mycolicibacterium › |
Proteomesi |
|
Subcellular locationi
- Cytoplasm UniRule annotation
GO - Cellular componenti
- chromosome Source: InterPro
- cytoplasm Source: UniProtKB-SubCell
Keywords - Cellular componenti
CytoplasmUniRule annotationARBA annotationInteractioni
Subunit structurei
Homodimer.
UniRule annotationProtein-protein interaction databases
STRINGi | 246196.MSMEI_2362 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 510 – 623 | SMC hingeInterPro annotationAdd BLAST | 114 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 255 – 289 | UniRule annotationAdd BLAST | 35 | |
Coiled coili | 329 – 374 | UniRule annotationAdd BLAST | 46 | |
Coiled coili | 459 – 486 | UniRule annotationAdd BLAST | 28 | |
Coiled coili | 654 – 681 | UniRule annotationAdd BLAST | 28 | |
Coiled coili | 738 – 765 | UniRule annotationAdd BLAST | 28 | |
Coiled coili | 880 – 921 | UniRule annotationAdd BLAST | 42 |
Domaini
Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.UniRule annotation
Sequence similaritiesi
Belongs to the SMC family.UniRule annotation
Keywords - Domaini
Coiled coilUniRule annotationARBA annotationPhylogenomic databases
eggNOGi | COG1196, Bacteria |
OMAi | HNKIAME |
OrthoDBi | 1149850at2 |
Family and domain databases
HAMAPi | MF_01894, Smc_prok, 1 hit |
InterProi | View protein in InterPro IPR027417, P-loop_NTPase IPR003395, RecF/RecN/SMC_N IPR024704, SMC IPR010935, SMC_hinge IPR036277, SMC_hinge_sf IPR011890, SMC_prok |
Pfami | View protein in Pfam PF06470, SMC_hinge, 1 hit PF02463, SMC_N, 1 hit |
PIRSFi | PIRSF005719, SMC, 1 hit |
SMARTi | View protein in SMART SM00968, SMC_hinge, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit SSF75553, SSF75553, 1 hit |
TIGRFAMsi | TIGR02168, SMC_prok_B, 1 hit |
i Sequence
Sequence statusi: Complete.
A0QV25-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MHLKSLTLKG FKSFASPTTL RFEPGITCVV GPNGSGKSNV VDALTWVMGE
60 70 80 90 100
QGAKTLRGGK MEDVIFAGTS SRAPLGRAEV TLTIDNSDNA LPIEYSEVSI
110 120 130 140 150
TRRMFRDGAG EYEINGASCR LMDVQELLSD SGIGREMHVI VGQGKLSEIL
160 170 180 190 200
ESRPEDRRAF IEEAAGVLKH RKRKEKAVRK LDSMAANLAR LTDLTTELRR
210 220 230 240 250
QLKPLGRQAE MARRAATIQA DLRDARLRLA ADDLVRRQVE FQNTNQAETA
260 270 280 290 300
LRKEHEELTV RLQSATVELQ AHEAAVAELT RRAEAAQQTW FRASALAERV
310 320 330 340 350
GATVRIATDR AQMLDSEPEM SSGRDPDALE AEAEEVAELE AQLLDELSEA
360 370 380 390 400
RIALETARAE LAEREQIAAD AERAHMAAAR AEADRREGLA RLAGQVDTMR
410 420 430 440 450
TRVESIDEGV LRLSVSIEEA AAKAEHAQAE FEDVQSRVGE LDAGEVGLDE
460 470 480 490 500
HHDRTVAALR LADERVAELQ AAERAAERQV ASLRARIEAL SVGLDRRDGA
510 520 530 540 550
AWLQKNHSGG GLFGSIGDFL RVQPGYEVAV AAVLGAAADA LAAENFGAAA
560 570 580 590 600
AAVAALKESD GGRAAIVLGD WNAIGSSPQA ALPPGATWAT DLVSVPDRLR
610 620 630 640 650
GAVTAMLTGV AVVPDMAAGL ALVSSRPELR AVTTEGDLVG PGWVSGGSDR
660 670 680 690 700
KPSTLEIASE IDKARAELEQ AERQTSELGA ALSGALAEQS ARQDAAEQAL
710 720 730 740 750
AALNESDAAI SAIYEQLARL GQEARGAHQE WQRLIKQRDE LEAGRTKTVE
760 770 780 790 800
ELRELESRLS NAEQTPMFDI EPVDRQETVA AAEAARAVEV EARLAVRTAE
810 820 830 840 850
ERANAVRGRA DSLRRAAAAE REARVRAQRA REAREYAARV AAAVSECGRQ
860 870 880 890 900
IAGKLSAVVA AAARSRDELA TERQLRVNAL GEIREEVTAL NNRINTLTDA
910 920 930 940 950
LHRDEMAKAQ AQLRIEQLEA QVLEQFGMSA GDLVAEYGPQ VALPPSELEM
960 970 980 990 1000
AEYEQAKERG EQVTAPAPMP FDRATQERRA KRAERELAEL GRVNPLALEE
1010 1020 1030 1040 1050
FAALEERYNF LSTQLEDVKA ARADLLDVIA DVDNRILQVF TEAYADVERE
1060 1070 1080 1090 1100
FEQVFATLFP GGEGRLLLTD PSDMLTTGIE VEARPPGKKI KRLSLLSGGE
1110 1120 1130 1140 1150
KSLTAVAMLV AIFRARPSPF YVMDEVEAAL DDVNLRRLIS LFEQLREKSQ
1160 1170 1180 1190
LIVITHQKPT MEIADALYGV TMRGDGITTV ISQRMRGQEL VSNPS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP000480 Genomic DNA Translation: ABK74599.1 |
RefSeqi | WP_011728333.1, NZ_SIJM01000012.1 YP_886763.1, NC_008596.1 |
Genome annotation databases
EnsemblBacteriai | ABK74599; ABK74599; MSMEG_2423 AFP38830; AFP38830; MSMEI_2362 |
GeneIDi | 45743976 |
KEGGi | msm:MSMEG_2423 |
PATRICi | fig|246196.19.peg.2388 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CP000480 Genomic DNA Translation: ABK74599.1 |
RefSeqi | WP_011728333.1, NZ_SIJM01000012.1 YP_886763.1, NC_008596.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 246196.MSMEI_2362 |
Proteomic databases
PRIDEi | A0QV25 |
Genome annotation databases
EnsemblBacteriai | ABK74599; ABK74599; MSMEG_2423 AFP38830; AFP38830; MSMEI_2362 |
GeneIDi | 45743976 |
KEGGi | msm:MSMEG_2423 |
PATRICi | fig|246196.19.peg.2388 |
Phylogenomic databases
eggNOGi | COG1196, Bacteria |
OMAi | HNKIAME |
OrthoDBi | 1149850at2 |
Family and domain databases
HAMAPi | MF_01894, Smc_prok, 1 hit |
InterProi | View protein in InterPro IPR027417, P-loop_NTPase IPR003395, RecF/RecN/SMC_N IPR024704, SMC IPR010935, SMC_hinge IPR036277, SMC_hinge_sf IPR011890, SMC_prok |
Pfami | View protein in Pfam PF06470, SMC_hinge, 1 hit PF02463, SMC_N, 1 hit |
PIRSFi | PIRSF005719, SMC, 1 hit |
SMARTi | View protein in SMART SM00968, SMC_hinge, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit SSF75553, SSF75553, 1 hit |
TIGRFAMsi | TIGR02168, SMC_prok_B, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0QV25_MYCS2 | |
Accessioni | A0QV25Primary (citable) accession number: A0QV25 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | January 9, 2007 |
Last sequence update: | January 9, 2007 | |
Last modified: | February 10, 2021 | |
This is version 107 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |