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Protein

30S ribosomal protein S4

Gene

rpsD

Organism
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.UniRule annotation
With S5 and S12 plays an important role in translational accuracy.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
30S ribosomal protein S4UniRule annotation
Gene namesi
Name:rpsDUniRule annotation
Ordered Locus Names:MSMEG_1523, MSMEI_1487
OrganismiMycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Taxonomic identifieri246196 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycolicibacterium
Proteomesi
  • UP000006158 Componenti: Chromosome
  • UP000000757 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003223111 – 20130S ribosomal protein S4Add BLAST201

Proteomic databases

PRIDEiA0QSL7

Interactioni

Subunit structurei

Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.UniRule annotation

Protein-protein interaction databases

STRINGi246196.MSMEG_1523

Structurei

Secondary structure

1201
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliA0QSL7
SMRiA0QSL7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini91 – 157S4 RNA-bindingUniRule annotationAdd BLAST67

Sequence similaritiesi

Belongs to the universal ribosomal protein uS4 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105G6W Bacteria
COG0522 LUCA
HOGENOMiHOG000221004
KOiK02986
OMAiNVVFRMG
OrthoDBiPOG091H00KS

Family and domain databases

CDDicd00165 S4, 1 hit
Gene3Di3.10.290.10, 1 hit
HAMAPiMF_01306_B Ribosomal_S4_B, 1 hit
InterProiView protein in InterPro
IPR022801 Ribosomal_S4/S9
IPR001912 Ribosomal_S4/S9_N
IPR005709 Ribosomal_S4_bac-type
IPR018079 Ribosomal_S4_CS
IPR002942 S4_RNA-bd
IPR036986 S4_RNA-bd_sf
PANTHERiPTHR11831 PTHR11831, 1 hit
PTHR11831:SF4 PTHR11831:SF4, 1 hit
PfamiView protein in Pfam
PF00163 Ribosomal_S4, 1 hit
PF01479 S4, 1 hit
SMARTiView protein in SMART
SM01390 Ribosomal_S4, 1 hit
SM00363 S4, 1 hit
TIGRFAMsiTIGR01017 rpsD_bact, 1 hit
PROSITEiView protein in PROSITE
PS00632 RIBOSOMAL_S4, 1 hit
PS50889 S4, 1 hit

Sequencei

Sequence statusi: Complete.

A0QSL7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MARYTGPATR KSRRLGVDLV GGDQSFEKRP YPPGQHGRAR IKESEYRQQL
60 70 80 90 100
QEKQKARFSY GVMEKQFRRY YEEANRQPGK TGDNLLRILE SRLDNVVYRA
110 120 130 140 150
GLARTRRMAR QLVSHGHFLV NGVKVDIPSY RVSQYDIIDV KEKSLNTLPF
160 170 180 190 200
QIARETAGER PIPSWLQVVG ERQRILVHQL PERAQIDVPL TEQLIVELYS

K
Length:201
Mass (Da):23,376
Last modified:January 9, 2007 - v1
Checksum:iF6AC4F66558E0968
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000480 Genomic DNA Translation: ABK70484.1
CP001663 Genomic DNA Translation: AFP37960.1
RefSeqiWP_003892911.1, NZ_CP009494.1
YP_885905.1, NC_008596.1

Genome annotation databases

EnsemblBacteriaiABK70484; ABK70484; MSMEG_1523
AFP37960; AFP37960; MSMEI_1487
GeneIDi4533059
KEGGimsb:LJ00_07610
msg:MSMEI_1487
msm:MSMEG_1523
PATRICifig|246196.19.peg.1508

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000480 Genomic DNA Translation: ABK70484.1
CP001663 Genomic DNA Translation: AFP37960.1
RefSeqiWP_003892911.1, NZ_CP009494.1
YP_885905.1, NC_008596.1

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5O5Jelectron microscopy3.45D1-201[»]
5O61electron microscopy3.31BD1-201[»]
5XYUelectron microscopy3.45D1-201[»]
5ZEBelectron microscopy3.40d1-201[»]
5ZEPelectron microscopy3.40d1-201[»]
5ZEUelectron microscopy3.70d1-201[»]
6DZIelectron microscopy3.46l2-201[»]
6DZKelectron microscopy3.60D1-201[»]
ProteinModelPortaliA0QSL7
SMRiA0QSL7
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi246196.MSMEG_1523

Proteomic databases

PRIDEiA0QSL7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABK70484; ABK70484; MSMEG_1523
AFP37960; AFP37960; MSMEI_1487
GeneIDi4533059
KEGGimsb:LJ00_07610
msg:MSMEI_1487
msm:MSMEG_1523
PATRICifig|246196.19.peg.1508

Phylogenomic databases

eggNOGiENOG4105G6W Bacteria
COG0522 LUCA
HOGENOMiHOG000221004
KOiK02986
OMAiNVVFRMG
OrthoDBiPOG091H00KS

Family and domain databases

CDDicd00165 S4, 1 hit
Gene3Di3.10.290.10, 1 hit
HAMAPiMF_01306_B Ribosomal_S4_B, 1 hit
InterProiView protein in InterPro
IPR022801 Ribosomal_S4/S9
IPR001912 Ribosomal_S4/S9_N
IPR005709 Ribosomal_S4_bac-type
IPR018079 Ribosomal_S4_CS
IPR002942 S4_RNA-bd
IPR036986 S4_RNA-bd_sf
PANTHERiPTHR11831 PTHR11831, 1 hit
PTHR11831:SF4 PTHR11831:SF4, 1 hit
PfamiView protein in Pfam
PF00163 Ribosomal_S4, 1 hit
PF01479 S4, 1 hit
SMARTiView protein in SMART
SM01390 Ribosomal_S4, 1 hit
SM00363 S4, 1 hit
TIGRFAMsiTIGR01017 rpsD_bact, 1 hit
PROSITEiView protein in PROSITE
PS00632 RIBOSOMAL_S4, 1 hit
PS50889 S4, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiRS4_MYCS2
AccessioniPrimary (citable) accession number: A0QSL7
Secondary accession number(s): I7F8S3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: January 9, 2007
Last modified: November 7, 2018
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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