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Protein
Submitted name:

Burkitt lymphoma receptor 1, GTP binding protein (Chemokine (C-X-C motif) receptor 5), isoform CRA_a

Gene

BLR1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Burkitt lymphoma receptor 1, GTP binding protein (Chemokine (C-X-C motif) receptor 5), isoform CRA_aImported
Submitted name:
C-x-c chemokine receptor type 5Imported
Gene namesi
Name:BLR1Imported
ORF Names:hCG_37947Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000160683.4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei52 – 76HelicalSequence analysisAdd BLAST25
Transmembranei88 – 108HelicalSequence analysisAdd BLAST21
Transmembranei131 – 151HelicalSequence analysisAdd BLAST21
Transmembranei163 – 182HelicalSequence analysisAdd BLAST20
Transmembranei220 – 239HelicalSequence analysisAdd BLAST20
Transmembranei260 – 281HelicalSequence analysisAdd BLAST22
Transmembranei301 – 325HelicalSequence analysisAdd BLAST25

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162383046

Expressioni

Gene expression databases

BgeeiENSG00000160683 Expressed in 98 organ(s), highest expression level in leukocyte
ExpressionAtlasiA0N0R2 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini68 – 322G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST255

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IE41 Eukaryota
ENOG410YWPA LUCA
HOVERGENiHBG106917
KOiK04190
OMAiINFYCSS
OrthoDBiEOG091G0EDT

Family and domain databases

CDDicd15181 7tmA_CXCR5, 1 hit
InterProiView protein in InterPro
IPR001053 Chemokine_CXCR5
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00564 CXCCHMKINER5
PR00237 GPCRRHODOPSN
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0N0R2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNYPLTLEMD LENLEDLFWE LDRLDNYNDT SLVENHLCPA TEGPLMASFK
60 70 80 90 100
AVFVPVAYSL IFLLGVIGNV LVLVILERHR QTRSSTETFL FHLAVADLLL
110 120 130 140 150
VFILPFAVAE GSVGWVLGTF LCKTVIALHK VNFYCSSLLL ACIAVDRYLA
160 170 180 190 200
IVHAVHAYRH RRLLSIHITC GTIWLVGFLL ALPEILFAKV SQGHHNNSLP
210 220 230 240 250
RCTFSQENQA ETHAWFTSRF LYHVAGFLLP MLVMGWCYVG VVHRLRQAQR
260 270 280 290 300
RPQRQKAVRV AILVTSIFFL CWSPYHIVIF LDTLARLKAV DNTCKLNGSL
310 320 330 340 350
PVAITMCEFL GLAHCCLNPM LYTFAGVKFR SDLSRLLTKL GCTGPASLCQ
360 370
LFPSWRRSSL SESENATSLT TF
Length:372
Mass (Da):41,955
Last modified:December 12, 2006 - v1
Checksum:i6DF84C839492ACCF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF064770 Genomic DNA Translation: ABK41953.1
EF444957 Genomic DNA Translation: ACA05956.1
CH471065 Genomic DNA Translation: EAW67415.1
RefSeqiNP_001707.1, NM_001716.4
UniGeneiHs.113916

Genome annotation databases

GeneIDi643
KEGGihsa:643

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF064770 Genomic DNA Translation: ABK41953.1
EF444957 Genomic DNA Translation: ACA05956.1
CH471065 Genomic DNA Translation: EAW67415.1
RefSeqiNP_001707.1, NM_001716.4
UniGeneiHs.113916

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

DNASUi643
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi643
KEGGihsa:643

Organism-specific databases

CTDi643
EuPathDBiHostDB:ENSG00000160683.4
PharmGKBiPA162383046

Phylogenomic databases

eggNOGiENOG410IE41 Eukaryota
ENOG410YWPA LUCA
HOVERGENiHBG106917
KOiK04190
OMAiINFYCSS
OrthoDBiEOG091G0EDT

Miscellaneous databases

ChiTaRSiCXCR5 human
GenomeRNAii643

Gene expression databases

BgeeiENSG00000160683 Expressed in 98 organ(s), highest expression level in leukocyte
ExpressionAtlasiA0N0R2 baseline and differential

Family and domain databases

CDDicd15181 7tmA_CXCR5, 1 hit
InterProiView protein in InterPro
IPR001053 Chemokine_CXCR5
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00564 CXCCHMKINER5
PR00237 GPCRRHODOPSN
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0N0R2_HUMAN
AccessioniPrimary (citable) accession number: A0N0R2
Entry historyiIntegrated into UniProtKB/TrEMBL: December 12, 2006
Last sequence update: December 12, 2006
Last modified: September 12, 2018
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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