BLR1

Functionⁱ

GO - Molecular functionⁱ

C-X-C chemokine receptor activity Source: InterPro

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

B cell activation Source: InterPro
immune response Source: InterPro
leukocyte chemotaxis Source: Ensembl
lymph node development Source: Ensembl

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	G-protein coupled receptorUniRule annotation, Receptor, Transducer

Molecular function

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Burkitt lymphoma receptor 1, GTP binding protein (Chemokine (C-X-C motif) receptor 5), isoform CRA_aImported Submitted name: C-x-c chemokine receptor type 5Imported
Gene namesⁱ	Name:BLR1Imported ORF Names:hCG_37947Imported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000160683.4

EuPathDBⁱ

HostDB:ENSG00000160683.4

Subcellular locationⁱ

GO - Cellular component

Topology

Feature key	Position(s)	DescriptionActions	Length
Transmembraneⁱ	52 – 76	HelicalSequence analysisAdd BLAST	25
Transmembraneⁱ	88 – 108	HelicalSequence analysisAdd BLAST	21
Transmembraneⁱ	131 – 151	HelicalSequence analysisAdd BLAST	21
Transmembraneⁱ	163 – 182	HelicalSequence analysisAdd BLAST	20
Transmembraneⁱ	220 – 239	HelicalSequence analysisAdd BLAST	20
Transmembraneⁱ	260 – 281	HelicalSequence analysisAdd BLAST	22
Transmembraneⁱ	301 – 325	HelicalSequence analysisAdd BLAST	25

Keywords - Cellular componentⁱ

Membrane

Pathology & Biotechⁱ

Organism-specific databases

PharmGKBⁱ	PA162383046

PharmGKBⁱ

PA162383046

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000160683 Expressed in 98 organ(s), highest expression level in leukocyte
ExpressionAtlasⁱ	A0N0R2 baseline and differential

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	68 – 322	G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST		255

Sequence similaritiesⁱ

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domainⁱ

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGⁱ	ENOG410IE41 Eukaryota ENOG410YWPA LUCA
HOVERGENⁱ	HBG106917
KEGG Orthology (KO) More...KOⁱ	K04190
OMAⁱ	INFYCSS
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0EDT

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd15181 7tmA_CXCR5, 1 hit
InterProⁱ	View protein in InterPro IPR001053 Chemokine_CXCR5 IPR000276 GPCR_Rhodpsn IPR017452 GPCR_Rhodpsn_7TM
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00001 7tm_1, 1 hit
PRINTSⁱ	PR00564 CXCCHMKINER5 PR00237 GPCRRHODOPSN
PROSITEⁱ	View protein in PROSITE PS00237 G_PROTEIN_RECEP_F1_1, 1 hit PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

A0N0R2-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MNYPLTLEMD LENLEDLFWE LDRLDNYNDT SLVENHLCPA TEGPLMASFK 
        60         70         80         90        100
AVFVPVAYSL IFLLGVIGNV LVLVILERHR QTRSSTETFL FHLAVADLLL 
       110        120        130        140        150
VFILPFAVAE GSVGWVLGTF LCKTVIALHK VNFYCSSLLL ACIAVDRYLA 
       160        170        180        190        200
IVHAVHAYRH RRLLSIHITC GTIWLVGFLL ALPEILFAKV SQGHHNNSLP 
       210        220        230        240        250
RCTFSQENQA ETHAWFTSRF LYHVAGFLLP MLVMGWCYVG VVHRLRQAQR 
       260        270        280        290        300
RPQRQKAVRV AILVTSIFFL CWSPYHIVIF LDTLARLKAV DNTCKLNGSL 
       310        320        330        340        350
PVAITMCEFL GLAHCCLNPM LYTFAGVKFR SDLSRLLTKL GCTGPASLCQ 
       360        370 
LFPSWRRSSL SESENATSLT TF

Length:372

Mass (Da):41,955

Last modified:December 12, 2006 - v1

Checksum:ⁱ6DF84C839492ACCF

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	EF064770 Genomic DNA Translation: ABK41953.1 EF444957 Genomic DNA Translation: ACA05956.1 CH471065 Genomic DNA Translation: EAW67415.1
NCBI Reference Sequences More...RefSeqⁱ	NP_001707.1, NM_001716.4
UniGeneⁱ	Hs.113916

Genome annotation databases

GeneIDⁱ	643
KEGGⁱ	hsa:643

Protein	Similar proteins		Species	Score	Length	Source
A0N0R2	C-X-C chemokine receptor type 5		HUMAN		372	UniRef100_P32302
Isoform Short of C-X-C chemokine receptor type 5		HUMAN		327

Protein	Similar proteins		Species	Score	Length	Source
A0N0R2	C-X-C chemokine receptor type 5		HUMAN		372	UniRef90_P32302
C-X-C motif chemokine receptor 5		PANTR		372
Uncharacterized protein		PANPA		372
C-X-C motif chemokine receptor 5		GORGO		372
C-X-C motif chemokine receptor 5		PONAB		372
+27

Protein	Similar proteins		Species	Score	Length	Source
A0N0R2	C-X-C chemokine receptor type 5		HUMAN		372	UniRef50_P32302
C-X-C chemokine receptor type 5		RAT		374
C-X-C chemokine receptor type 5		MOUSE		374
C-X-C motif chemokine receptor 5		MACMU		372
C-X-C motif chemokine receptor 5		MACFA		372
+115

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	EF064770 Genomic DNA Translation: ABK41953.1 EF444957 Genomic DNA Translation: ACA05956.1 CH471065 Genomic DNA Translation: EAW67415.1
RefSeqⁱ	NP_001707.1, NM_001716.4
UniGeneⁱ	Hs.113916

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein family/group databases

GPCRDBⁱ	Search...

GPCRDBⁱ

Search...

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	643
Structural Biology Knowledgebase	Search...

Genome annotation databases

GeneIDⁱ	643
KEGGⁱ	hsa:643

Organism-specific databases

CTDⁱ	643
EuPathDBⁱ	HostDB:ENSG00000160683.4
PharmGKBⁱ	PA162383046

Phylogenomic databases

eggNOGⁱ	ENOG410IE41 Eukaryota ENOG410YWPA LUCA
HOVERGENⁱ	HBG106917
KOⁱ	K04190
OMAⁱ	INFYCSS
OrthoDBⁱ	EOG091G0EDT

Miscellaneous databases

ChiTaRSⁱ	CXCR5 human
GenomeRNAiⁱ	643

Gene expression databases

Bgeeⁱ	ENSG00000160683 Expressed in 98 organ(s), highest expression level in leukocyte
ExpressionAtlasⁱ	A0N0R2 baseline and differential

Family and domain databases

CDDⁱ	cd15181 7tmA_CXCR5, 1 hit
InterProⁱ	View protein in InterPro IPR001053 Chemokine_CXCR5 IPR000276 GPCR_Rhodpsn IPR017452 GPCR_Rhodpsn_7TM
Pfamⁱ	View protein in Pfam PF00001 7tm_1, 1 hit
PRINTSⁱ	PR00564 CXCCHMKINER5 PR00237 GPCRRHODOPSN
PROSITEⁱ	View protein in PROSITE PS00237 G_PROTEIN_RECEP_F1_1, 1 hit PS50262 G_PROTEIN_RECEP_F1_2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	A0N0R2_HUMAN
Accessionⁱ	A0N0R2Primary (citable) accession number: A0N0R2
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	December 12, 2006
	Last sequence update:	December 12, 2006
	Last modified:	September 12, 2018
	This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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UniProtKB - A0N0R2 (A0N0R2_HUMAN)

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Burkitt lymphoma receptor 1, GTP binding protein (Chemokine (C-X-C motif) receptor 5), isoform CRA_a

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Plasma Membrane

Other locations

Topology

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein family/group databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

Expressionⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ