UniProtKB - A0M8W4 (A0M8W4_HUMAN)
Protein
Submitted name:
Ubiquitin-conjugating enzyme E2 variant 2
Gene
UBE2V2
Organism
Homo sapiens (Human)
Status
Functioni
GO - Biological processi
- error-free postreplication DNA repair Source: Ensembl
- negative regulation of neuron apoptotic process Source: Ensembl
- positive regulation of DNA repair Source: Ensembl
- positive regulation of neuron projection development Source: Ensembl
- positive regulation of proteasomal ubiquitin-dependent protein catabolic process Source: Ensembl
- positive regulation of synapse assembly Source: Ensembl
Names & Taxonomyi
Protein namesi | Submitted name: Ubiquitin-conjugating enzyme E2 variant 2ImportedSubmitted name: Ubiquitin-conjugating enzyme E2 variant 2, isoform CRA_bImportedSubmitted name: cDNA, FLJ93989, Homo sapiens ubiquitin-conjugating enzyme E2 variant 2 (UBE2V2),mRNAImported |
Gene namesi | Name:UBE2V2Imported ORF Names:hCG_1640505Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Organism-specific databases
VEuPathDBi | HostDB:ENSG00000169139.11 |
Expressioni
Gene expression databases
Bgeei | ENSG00000169139, Expressed in anterior cingulate cortex and 248 other tissues |
ExpressionAtlasi | A0M8W4, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 13 – 138 | UBC coreInterPro annotationAdd BLAST | 126 |
Phylogenomic databases
HOGENOMi | CLU_063065_3_0_1 |
OMAi | WQSSYSI |
OrthoDBi | 1507995at2759 |
Family and domain databases
Gene3Di | 3.10.110.10, 1 hit |
InterProi | View protein in InterPro IPR000608, UBQ-conjugat_E2 IPR016135, UBQ-conjugating_enzyme/RWD |
Pfami | View protein in Pfam PF00179, UQ_con, 1 hit |
SUPFAMi | SSF54495, SSF54495, 1 hit |
PROSITEi | View protein in PROSITE PS50127, UBIQUITIN_CONJUGAT_2, 1 hit |
i Sequence
Sequence statusi: Complete.
A0M8W4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAVSTGVKVP RNFRLLEELE EGQKGVGDGT VSWGLEDDED MTLTRWTGMI
60 70 80 90 100
IGPPRTNYEN RIYSLKVECG PKYPEAPPSV RFVTKINMNG INNSSGMVDA
110 120 130 140
RSIPVLAKWQ NSYSIKVVLQ ELRRLMMSKE NMKLPQPPEG QTYNN
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | DQ003720 Genomic DNA Translation: AAY16979.1 AK313447 mRNA Translation: BAG36236.1 CH471068 Genomic DNA Translation: EAW86688.1 |
RefSeqi | NP_003341.1, NM_003350.2 |
Genome annotation databases
GeneIDi | 7336 |
KEGGi | hsa:7336 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | DQ003720 Genomic DNA Translation: AAY16979.1 AK313447 mRNA Translation: BAG36236.1 CH471068 Genomic DNA Translation: EAW86688.1 |
RefSeqi | NP_003341.1, NM_003350.2 |
3D structure databases
SMRi | A0M8W4 |
ModBasei | Search... |
Proteomic databases
PRIDEi | A0M8W4 |
Protocols and materials databases
Antibodypediai | 24348, 301 antibodies |
DNASUi | 7336 |
Genome annotation databases
GeneIDi | 7336 |
KEGGi | hsa:7336 |
Organism-specific databases
CTDi | 7336 |
PharmGKBi | PA37143 |
VEuPathDBi | HostDB:ENSG00000169139.11 |
Phylogenomic databases
HOGENOMi | CLU_063065_3_0_1 |
OMAi | WQSSYSI |
OrthoDBi | 1507995at2759 |
Miscellaneous databases
BioGRID-ORCSi | 7336, 10 hits in 961 CRISPR screens |
ChiTaRSi | UBE2V2, human |
GenomeRNAii | 7336 |
Gene expression databases
Bgeei | ENSG00000169139, Expressed in anterior cingulate cortex and 248 other tissues |
ExpressionAtlasi | A0M8W4, baseline and differential |
Family and domain databases
Gene3Di | 3.10.110.10, 1 hit |
InterProi | View protein in InterPro IPR000608, UBQ-conjugat_E2 IPR016135, UBQ-conjugating_enzyme/RWD |
Pfami | View protein in Pfam PF00179, UQ_con, 1 hit |
SUPFAMi | SSF54495, SSF54495, 1 hit |
PROSITEi | View protein in PROSITE PS50127, UBIQUITIN_CONJUGAT_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0M8W4_HUMAN | |
Accessioni | A0M8W4Primary (citable) accession number: A0M8W4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | December 12, 2006 |
Last sequence update: | December 12, 2006 | |
Last modified: | April 7, 2021 | |
This is version 125 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |