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Protein

60 kDa chaperonin 1

Gene

groL1

Organism
Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciACEL351607:G1G7K-107-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperonin 1UniRule annotation
Alternative name(s):
GroEL protein 1UniRule annotation
Protein Cpn60 1UniRule annotation
Gene namesi
Name:groL1UniRule annotation
Synonyms:groEL1UniRule annotation
Ordered Locus Names:Acel_0101
OrganismiAcidothermus cellulolyticus (strain ATCC 43068 / 11B)
Taxonomic identifieri351607 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaAcidothermalesAcidothermaceaeAcidothermus
Proteomesi
  • UP000008221 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003319611 – 53960 kDa chaperonin 1Add BLAST539

Proteomic databases

PRIDEiA0LR17

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Protein-protein interaction databases

STRINGi351607.Acel_0101

Structurei

3D structure databases

ProteinModelPortaliA0LR17
SMRiA0LR17
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CJ9 Bacteria
COG0459 LUCA
HOGENOMiHOG000076290
KOiK04077
OMAiTDTDKME
OrthoDBiPOG091H00E7

Family and domain databases

CDDicd03344 GroEL, 1 hit
Gene3Di1.10.560.10, 2 hits
3.30.260.10, 2 hits
3.50.7.10, 1 hit
HAMAPiMF_00600 CH60, 1 hit
InterProiView protein in InterPro
IPR018370 Chaperonin_Cpn60_CS
IPR001844 Chaprnin_Cpn60
IPR002423 Cpn60/TCP-1
IPR027409 GroEL-like_apical_dom_sf
IPR027413 GROEL-like_equatorial_sf
IPR027410 TCP-1-like_intermed_sf
PfamiView protein in Pfam
PF00118 Cpn60_TCP1, 1 hit
PRINTSiPR00298 CHAPERONIN60
SUPFAMiSSF48592 SSF48592, 2 hits
SSF52029 SSF52029, 1 hit
SSF54849 SSF54849, 1 hit
TIGRFAMsiTIGR02348 GroEL, 1 hit
PROSITEiView protein in PROSITE
PS00296 CHAPERONINS_CPN60, 1 hit

Sequencei

Sequence statusi: Complete.

A0LR17-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKMIAFDEA ARRALERGMN QLADAVKVTL GPKGRNVVLE KKWGAPTITN
60 70 80 90 100
DGVSIAKEIE LEDPYEKIGA ELVKEVAKKT DDVAGDGTTT ATVLAQTLVR
110 120 130 140 150
EGLRNVAAGA NPMALKRGIE AATERVCQAL LEIAKDVETR EQIASTASIS
160 170 180 190 200
AGDTAVGEMI AEAMDKVGKE GVITVEESNT FGLELELTEG MRFDKGYISP
210 220 230 240 250
YFVTDSERME AVLEDPYILI ANQKISAVKD LLPVLEKVMQ AGKPLAIIAE
260 270 280 290 300
DVEGEALATL VVNKIRGTFR SVAVKAPGFG DRRKAMLGDI AVLTGGQVIS
310 320 330 340 350
EEVGLKLENV GLDLLGRARK VVVTKDETTI VEGAGDPEQI AGRVNQIRAE
360 370 380 390 400
IEKTDSDYDR EKLQERLAKL AGGVAVIKVG AATEVELKER KHRIEDAVRN
410 420 430 440 450
AKAAVEEGIV AGGGVALLQA GKTAFEKLDL EGDEATGARI VELALEAPLK
460 470 480 490 500
QIAINAGLEG GVVVEKVRSL EPGWGLNAQT GEYVDMIKAG IIDPAKVTRS
510 520 530
ALQNAASIAG LFLTTEAVVA EKPEKEKTPA APGGGDMDF
Length:539
Mass (Da):57,154
Last modified:December 12, 2006 - v1
Checksum:i84ACA73AB7F72F08
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000481 Genomic DNA Translation: ABK51877.1
RefSeqiWP_011718941.1, NC_008578.1

Genome annotation databases

EnsemblBacteriaiABK51877; ABK51877; Acel_0101
KEGGiace:Acel_0101

Similar proteinsi

Entry informationi

Entry nameiCH601_ACIC1
AccessioniPrimary (citable) accession number: A0LR17
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: December 12, 2006
Last modified: May 23, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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