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Entry version 62 (13 Feb 2019)
Sequence version 1 (12 Dec 2006)
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Protein
Submitted name:

ImcF family protein

Gene

AHA_1845

Organism
Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / JCM 1027 / KCTC 2358 / NCIMB 9240)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
AHYD380703:G1G7B-1844-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
ImcF family proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:AHA_1845Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAeromonas hydrophila subsp. hydrophila (strain ATCC 7966 / DSM 30187 / JCM 1027 / KCTC 2358 / NCIMB 9240)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri380703 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAeromonadalesAeromonadaceaeAeromonas
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000756 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei20 – 38HelicalSequence analysisAdd BLAST19
Transmembranei58 – 76HelicalSequence analysisAdd BLAST19
Transmembranei446 – 467HelicalSequence analysisAdd BLAST22

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
380703.AHA_1845

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini201 – 450ImcF-related_NInterPro annotationAdd BLAST250
Domaini502 – 815IcmF-relatedInterPro annotationAdd BLAST314
Domaini914 – 1109IcmF_CInterPro annotationAdd BLAST196

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG4105CU3 Bacteria
COG3523 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000276458

KEGG Orthology (KO)

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KOi
K11891

Identification of Orthologs from Complete Genome Data

More...
OMAi
FFGYGGT

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR009612 IcmF-related
IPR025743 IcmF-related_N_dom
IPR010623 IcmF_C
IPR027417 P-loop_NTPase
IPR017731 T6SS_IcmF

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF06761 IcmF-related, 1 hit
PF06744 IcmF_C, 1 hit
PF14331 ImcF-related_N, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR03348 VI_IcmF, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0KJC8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFKTIFTFLR QQLPKLKPSW PLLGAVLWVL ALILVWWLGP RLEVRGAKPF
60 70 80 90 100
EPLWGRVVFT LLWLWLLLGV VSWRVWRKMQ QLKAERQHEV VLEQDPVKGL
110 120 130 140 150
IDRQALFLDR WLQALNTHLG KGALYAMPWY LVLGLPGSGK SSLIHRANPA
160 170 180 190 200
NKLNPRLDTE LRDVAQDQLV DCWLGEQAVM LDPAGVLLSQ SEAELDPQAR
210 220 230 240 250
KHERLWLHLL GWLNEHRRRQ PLNGLVLTVD LAWLSHASVA ERKAYAQLMR
260 270 280 290 300
SRLQEVSATM NTRLPLYVTF TKLDLLRGFD VIYQQLDKEA RDAVLGVTFK
310 320 330 340 350
PGADWQQDLA LFWDQWVDNL NQNLPELMLS RLDAAQRNAL FSFVRQLAGL
360 370 380 390 400
KDYVTSLLAE TLAIEESKPL LVRGVYVSSV YQQGVPFDAF AQAASRRYNL
410 420 430 440 450
PEPIHSALRG ESNTYFVRQL FSSIIFPEAH LAGENRLHTL YRRRRMAIGL
460 470 480 490 500
SCLSLFSAAL IGGWHYFYRV NEEAGRNVLT KAQAFMETNE VADAHAFGVS
510 520 530 540 550
QLPRLNLIRE ATLSFGNYRE RMPLVADLGL YQGDEIGPYV EGSYLQLLSL
560 570 580 590 600
RFLPAQMQGL LADLNQAPAG SEEKLAILRV MRMLDDASGR NKELVAQYMA
610 620 630 640 650
SRWQKAFPGQ GAVQEQLMGH LDYALDHTNW YGARAERDQA AITAFVPFKE
660 670 680 690 700
PVYGAQRELG KLPMYQRVYQ NLVVKAGDVL PPDLNVRDEV GPTFDTVFAL
710 720 730 740 750
RSDNAGQVPR LLTWPGFNDF FLKQDKALID LTAMDAWVLG QRKLSQLSEA
760 770 780 790 800
DRKEITRQVN DRYVTDYVNQ WQKLLTNLDV QTLESPEQAL DVLAAITGND
810 820 830 840 850
QPFQRVLASL DDNTRIRKIS DVEGDPAQAI SARIGRPFMA TNGVLAGRGE
860 870 880 890 900
QGPLIQEVNQ KLVELQHYLE LIVNATEPGQ SALKAVQLRM TNKYADPVFA
910 920 930 940 950
LQQYARSLPA PLDRWVGQLS EQSSRLVIDL AMSSLNQEWQ DKVLTPFNSQ
960 970 980 990 1000
LAGRYPFDPS SNKDVPLSEM ERFFAPNGTL DSFYQVNLKP MVESGLMEGE
1010 1020 1030 1040 1050
FSSPIQAELV KQLDRAARIR QIFFSQQGNL EVQFALEPIE LTANKRRSVL
1060 1070 1080 1090 1100
NLDGQLLEYA HGRRTKIPLV WPNTMRDGAE SKITLVPAAR ERSPRSEGFV
1110 1120 1130 1140 1150
GPWAMFRLMD KGELTQVNDA TFDVRFPVDQ GAMTYRVYTD SAQNPFTGGL
1160
FSQFRLPESL Y
Length:1,161
Mass (Da):131,747
Last modified:December 12, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i675BA0C8581BA11E
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP000462 Genomic DNA Translation: ABK37153.1

NCBI Reference Sequences

More...
RefSeqi
WP_011705725.1, NC_008570.1
YP_856379.1, NC_008570.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
ABK37153; ABK37153; AHA_1845

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
4489199

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
aha:AHA_1845

Pathosystems Resource Integration Center (PATRIC)

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PATRICi
fig|380703.7.peg.1859

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000462 Genomic DNA Translation: ABK37153.1
RefSeqiWP_011705725.1, NC_008570.1
YP_856379.1, NC_008570.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi380703.AHA_1845

Genome annotation databases

EnsemblBacteriaiABK37153; ABK37153; AHA_1845
GeneIDi4489199
KEGGiaha:AHA_1845
PATRICifig|380703.7.peg.1859

Phylogenomic databases

eggNOGiENOG4105CU3 Bacteria
COG3523 LUCA
HOGENOMiHOG000276458
KOiK11891
OMAiFFGYGGT

Enzyme and pathway databases

BioCyciAHYD380703:G1G7B-1844-MONOMER

Family and domain databases

InterProiView protein in InterPro
IPR009612 IcmF-related
IPR025743 IcmF-related_N_dom
IPR010623 IcmF_C
IPR027417 P-loop_NTPase
IPR017731 T6SS_IcmF
PfamiView protein in Pfam
PF06761 IcmF-related, 1 hit
PF06744 IcmF_C, 1 hit
PF14331 ImcF-related_N, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR03348 VI_IcmF, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0KJC8_AERHH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0KJC8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: December 12, 2006
Last sequence update: December 12, 2006
Last modified: February 13, 2019
This is version 62 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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