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Protein
Submitted name:

SCUBE1 protein

Gene

SCUBE1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

Keywordsi

LigandCalciumSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
SCUBE1 proteinImported
Gene namesi
Name:SCUBE1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_500262535524 – 363Sequence analysisAdd BLAST340

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PeptideAtlasiA0JP65
PRIDEiA0JP65

Expressioni

Gene expression databases

GenevisibleiA0JP65 HS

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini33 – 73EGF-likeInterPro annotationAdd BLAST41
Domaini74 – 116EGF-likeInterPro annotationAdd BLAST43
Domaini117 – 153EGF-likeInterPro annotationAdd BLAST37
Domaini282 – 322EGF-likeInterPro annotationAdd BLAST41

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotationSAAS annotation, RepeatSAAS annotation, SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IR7D Eukaryota
ENOG411030G LUCA
HOVERGENiHBG067450

Family and domain databases

InterProiView protein in InterPro
IPR001881 EGF-like_Ca-bd_dom
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR000152 EGF-type_Asp/Asn_hydroxyl_site
IPR018097 EGF_Ca-bd_CS
IPR024731 EGF_dom
IPR009030 Growth_fac_rcpt_cys_sf
PfamiView protein in Pfam
PF12947 EGF_3, 1 hit
PF07645 EGF_CA, 1 hit
SMARTiView protein in SMART
SM00181 EGF, 7 hits
SM00179 EGF_CA, 6 hits
SUPFAMiSSF57184 SSF57184, 1 hit
PROSITEiView protein in PROSITE
PS00010 ASX_HYDROXYL, 4 hits
PS01186 EGF_2, 3 hits
PS50026 EGF_3, 4 hits
PS01187 EGF_CA, 2 hits

Sequencei

Sequence statusi: Complete.

A0JP65-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGAAAVRWHL CVLLALGTRG RLAGGSGLPG SVDVDECSEG TDDCHIDAIC
60 70 80 90 100
QNTPKSYKCL CKPGYKGEGK QCEDIDECEN DYYNGGCVHE CINIPGNYRC
110 120 130 140 150
TCFDGFMLAH DGHNCLDVDE CQDNNGGCQQ ICVNAMGSYE CQCHSGFFLS
160 170 180 190 200
DNQHTCIHRS NEGMNCMNKD HGCAHICRET PKGGVACDCR PGFDLAQNQK
210 220 230 240 250
DCTLTCNYGN GGCQHSCEDT DTGPMCGCHQ KYALHSDGRT CIETCAVNNG
260 270 280 290 300
GCDRTCKDTA TGVRCSCPVG FTLQPDGKTC KDINECLVNN GGCDHFCRNT
310 320 330 340 350
VGSFECGCRK GYKLLTDERT CQDIDECSFE RTCDHICINS PGSFQCLIKL
360
LRSKVSRFLR PYK
Length:363
Mass (Da):39,587
Last modified:December 12, 2006 - v1
Checksum:i4BDB05A699BE5FBE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC127263 mRNA Translation: AAI27264.1
RefSeqiNP_766638.2, NM_173050.3
UniGeneiHs.133995

Genome annotation databases

GeneIDi80274
KEGGihsa:80274

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC127263 mRNA Translation: AAI27264.1
RefSeqiNP_766638.2, NM_173050.3
UniGeneiHs.133995

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiA0JP65
PRIDEiA0JP65

Protocols and materials databases

DNASUi80274
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi80274
KEGGihsa:80274

Organism-specific databases

CTDi80274

Phylogenomic databases

eggNOGiENOG410IR7D Eukaryota
ENOG411030G LUCA
HOVERGENiHBG067450

Miscellaneous databases

GenomeRNAii80274

Gene expression databases

GenevisibleiA0JP65 HS

Family and domain databases

InterProiView protein in InterPro
IPR001881 EGF-like_Ca-bd_dom
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR000152 EGF-type_Asp/Asn_hydroxyl_site
IPR018097 EGF_Ca-bd_CS
IPR024731 EGF_dom
IPR009030 Growth_fac_rcpt_cys_sf
PfamiView protein in Pfam
PF12947 EGF_3, 1 hit
PF07645 EGF_CA, 1 hit
SMARTiView protein in SMART
SM00181 EGF, 7 hits
SM00179 EGF_CA, 6 hits
SUPFAMiSSF57184 SSF57184, 1 hit
PROSITEiView protein in PROSITE
PS00010 ASX_HYDROXYL, 4 hits
PS01186 EGF_2, 3 hits
PS50026 EGF_3, 4 hits
PS01187 EGF_CA, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiA0JP65_HUMAN
AccessioniPrimary (citable) accession number: A0JP65
Entry historyiIntegrated into UniProtKB/TrEMBL: December 12, 2006
Last sequence update: December 12, 2006
Last modified: January 31, 2018
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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