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Entry version 92 (31 Jul 2019)
Sequence version 1 (12 Dec 2006)
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Protein
Submitted name:

Zgc:153456

Gene

n4bp2

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Zgc:153456Imported
Submitted name:
Zgc:153456 proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:n4bp2Imported
Synonyms:zgc:153456Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7955 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

Zebrafish Information Network genome database

More...
ZFINi
ZDB-GENE-061103-451 n4bp2

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini60 – 103CUEInterPro annotationAdd BLAST44
Domaini1048 – 1091CUEInterPro annotationAdd BLAST44
Domaini1613 – 1692SmrInterPro annotationAdd BLAST80

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 33DisorderedSequence analysisAdd BLAST33
Regioni203 – 250DisorderedSequence analysisAdd BLAST48
Regioni741 – 761DisorderedSequence analysisAdd BLAST21
Regioni850 – 918DisorderedSequence analysisAdd BLAST69
Regioni1134 – 1194DisorderedSequence analysisAdd BLAST61
Regioni1246 – 1311DisorderedSequence analysisAdd BLAST66
Regioni1498 – 1541DisorderedSequence analysisAdd BLAST44

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi11 – 33PolarSequence analysisAdd BLAST23
Compositional biasi742 – 761PolarSequence analysisAdd BLAST20
Compositional biasi872 – 887PolarSequence analysisAdd BLAST16
Compositional biasi888 – 918PolyampholyteSequence analysisAdd BLAST31
Compositional biasi1134 – 1177PolarSequence analysisAdd BLAST44
Compositional biasi1281 – 1306PolyampholyteSequence analysisAdd BLAST26
Compositional biasi1513 – 1531PolyampholyteSequence analysisAdd BLAST19

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2401 Eukaryota
ENOG41101K4 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000170116

KEGG Orthology (KO)

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KOi
K15720

Database of Orthologous Groups

More...
OrthoDBi
76267at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd14365 CUE_N4BP2, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003892 CUE
IPR013899 DUF1771
IPR041801 N4BP2_CUE
IPR027417 P-loop_NTPase
IPR002625 Smr_dom
IPR036063 Smr_dom_sf
IPR009060 UBA-like_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02845 CUE, 1 hit
PF08590 DUF1771, 1 hit
PF01713 Smr, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00546 CUE, 2 hits
SM01162 DUF1771, 1 hit
SM00463 SMR, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF160443 SSF160443, 1 hit
SSF46934 SSF46934, 1 hit
SSF52540 SSF52540, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51140 CUE, 2 hits
PS50828 SMR, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0JMG4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPKKKKNGHS PSRAPMQSAE YGSGSESRAY GTNGSFVTRA GATHLGSSTH
60 70 80 90 100
YSSGRVESQS RDEIIQRMQE MFSHLDPEVI CMVLSEVDFK VDNAMDSLLE
110 120 130 140 150
MSDAAEGIAP PSPPLSGFEQ AAALLRTNTT QTDLLSGTAQ RFVFSNQPRS
160 170 180 190 200
QPELSPDETC LTEEFDALLD QELQTLTTQQ MQASSHSPVS SIPLSSLPSS
210 220 230 240 250
SQLLSLASQP QCPAPQSLAE HAEHVSYSDP GLSEARGGSS PVNELSFGGG
260 270 280 290 300
HIPETKTISL DFSHLTLEAN STEPRPSAFQ VYRRPDQLHN HAGAKKHQES
310 320 330 340 350
LSTPAMFWNT QAAEFHPHSM GPPFITPVIP NPTPWSSNPI PASQWLTHAT
360 370 380 390 400
VRQAPLKPSA TVPKSWTLPT RHRLKLEGQV LVLLRGAPGS GKTTLANAML
410 420 430 440 450
AQNPGGVVLS TDEYFMRNGH YYFEPNLLGE AHEWNHQRAK DAFEKGRSPI
460 470 480 490 500
IIDNTNTQCW EMKPYVAMAQ KHRYKVLFRE PDTWWKTKPR ELEKRTRHQV
510 520 530 540 550
TKEKIRRMLE RYDRFVSVQT IMNSNKPEPV PSVAALTQIE TEQPQQFLHP
560 570 580 590 600
GLTHPDLVGD SDLSKLNLHL SSSLPDVSSV SQIYNTTSAG EEESEMALYT
610 620 630 640 650
CKESMLTCEN VQEDARTPQS DLLDSEGLDS ELDACLVDTD KEFSNLRSGI
660 670 680 690 700
NEEYIVSEHE TFHEPPVAFS ESIAQRIRKV RENDRKPQVK SVIDQPVNLD
710 720 730 740 750
PILDSSEPKK EKRCEGEPFV EDKVVRPELL DFVGDWPLVS QDQRQGRCQN
760 770 780 790 800
SRNNIFNNSG LEASVVEHQD NKDKDKDGQD KDVSTDSTAE FQKLVDLLQG
810 820 830 840 850
GGRNSFPDFY HTPASNTLTT LQSSLLSVKE SDRDLEPMVL PELPDCVLER
860 870 880 890 900
KYSEGTNPRK DYIYSPSTPE QGADPIGPSN QMSSEKSTQD EIEQEDNGKG
910 920 930 940 950
SKVVIDSEGS LERRKGLSRR SGKSCKLALT FTNQSTSSPC SQSPVVSHLP
960 970 980 990 1000
SEITPAGGTP SLPMLCSSTS AQTYPQDFAL LWRIDQQKSF ELASDSSNSR
1010 1020 1030 1040 1050
MFVLEGNSLR FTPKINEEES AWQHRVPYRV VHEKGSQVED NDFRESNSKQ
1060 1070 1080 1090 1100
QNLEILSGHF RHVSVDILED LYEKCHQDIE WTTNLLLDSG ERLYKEDNEV
1110 1120 1130 1140 1150
DLGSLVPMQE SCELSIKPTE TVVCSQSDQA RALLSDDSSN SSLSSISPKS
1160 1170 1180 1190 1200
QETNPSEVSP ASDDWSPGQS SLSDAEGYDE ESMTEEICES EPSHETVKQL
1210 1220 1230 1240 1250
KEDTKIQLAV PAIKEELAEK TGEQDAGLQD TLVSQSEQIV RLLEEDLKEW
1260 1270 1280 1290 1300
KEEEGGGEER EDDETKAEVN ALTQLLLSQV DEMEQKEEEE RKERENERRR
1310 1320 1330 1340 1350
TGLGKREQSS MDIQSLELKL PTELALQLTE LFGPVGISPG AFSSDDCAVQ
1360 1370 1380 1390 1400
IDLNLAKLLH QKWKETIQEK HRLAALSYQL MQECPTQWGS KSKLRDQTAL
1410 1420 1430 1440 1450
HEEIPFMDHW NASCAPVSLR DIMIEEQVMQ DSVEKCRSSR KDLDKKDSAA
1460 1470 1480 1490 1500
KLKENQLFSM FPTIDRHFLR DIFRDHNYSL EQTEQFLQTL LDDGPVKNVV
1510 1520 1530 1540 1550
APEPSPQRNG TYRAPSKERK WKSRDGEVDA AQFQDSEDPE YDDFRTEATL
1560 1570 1580 1590 1600
QRRQQIECFN KAAEAHRQGR KDVASFYAQQ GHMHGEKMRE ANHRAAMQIF
1610 1620 1630 1640 1650
QQVNASLLPQ NILDLHGLHV DEAIHHLSQV LLDKCLEFHQ GVCPPQLSVI
1660 1670 1680 1690
TGRGNRSQGG VARIRPAVLD YLKNQHYSYT EPKIGLVLVT LH
Length:1,692
Mass (Da):189,756
Last modified:December 12, 2006 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEDA1A135F4DC8305
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BC125868 mRNA Translation: AAI25869.1
BC165684 mRNA Translation: AAI65684.1

NCBI Reference Sequences

More...
RefSeqi
NP_001073436.1, NM_001079967.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

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GeneIDi
558048

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dre:558048

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC125868 mRNA Translation: AAI25869.1
BC165684 mRNA Translation: AAI65684.1
RefSeqiNP_001073436.1, NM_001079967.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

GeneIDi558048
KEGGidre:558048

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
55728
ZFINiZDB-GENE-061103-451 n4bp2

Phylogenomic databases

eggNOGiKOG2401 Eukaryota
ENOG41101K4 LUCA
HOGENOMiHOG000170116
KOiK15720
OrthoDBi76267at2759

Family and domain databases

CDDicd14365 CUE_N4BP2, 1 hit
InterProiView protein in InterPro
IPR003892 CUE
IPR013899 DUF1771
IPR041801 N4BP2_CUE
IPR027417 P-loop_NTPase
IPR002625 Smr_dom
IPR036063 Smr_dom_sf
IPR009060 UBA-like_sf
PfamiView protein in Pfam
PF02845 CUE, 1 hit
PF08590 DUF1771, 1 hit
PF01713 Smr, 1 hit
SMARTiView protein in SMART
SM00546 CUE, 2 hits
SM01162 DUF1771, 1 hit
SM00463 SMR, 1 hit
SUPFAMiSSF160443 SSF160443, 1 hit
SSF46934 SSF46934, 1 hit
SSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS51140 CUE, 2 hits
PS50828 SMR, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0JMG4_DANRE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0JMG4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: December 12, 2006
Last sequence update: December 12, 2006
Last modified: July 31, 2019
This is version 92 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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